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Q5SVY1

- Q5SVY1_MOUSE

UniProt

Q5SVY1 - Q5SVY1_MOUSE

Protein
Submitted name:

2-oxoglutarate dehydrogenase, mitochondrial

Gene

Ogdh

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. oxoglutarate dehydrogenase (NAD+) activity Source: MGI
    2. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
    3. thiamine pyrophosphate binding Source: InterPro

    GO - Biological processi

    1. 2-oxoglutarate metabolic process Source: Ensembl
    2. NADH metabolic process Source: Ensembl
    3. succinyl-CoA metabolic process Source: Ensembl
    4. tricarboxylic acid cycle Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    2-oxoglutarate dehydrogenase, mitochondrialImported
    Gene namesi
    Name:OgdhImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:1098267. Ogdh.

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrion Source: MGI
    2. oxoglutarate dehydrogenase complex Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ5SVY1.

    Expressioni

    Gene expression databases

    ArrayExpressiQ5SVY1.

    Family & Domainsi

    Phylogenomic databases

    GeneTreeiENSGT00530000063092.
    InParanoidiQ5SVY1.

    Family and domain databases

    InterProiIPR011603. 2oxoglutarate_DH_E1.
    [Graphical view]
    PANTHERiPTHR23152. PTHR23152. 1 hit.

    Sequencei

    Sequence statusi: Fragment.

    Q5SVY1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFHLRTCAAK LRPLTASQTV KTFSQNKPAA IRTFQQIRCY SAPVAAEPFL   50
    SGTSSNYVEE MYCAWLENPK SVHKSWDIFF RNTN 84
    Length:84
    Mass (Da):9,634
    Last modified:December 21, 2004 - v1
    Checksum:i8888A3C7C7159DD4
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei84 – 841Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL607152 Genomic DNA. No translation available.

    Genome annotation databases

    EnsembliENSMUST00000135124; ENSMUSP00000117505; ENSMUSG00000020456.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL607152 Genomic DNA. No translation available.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5SVY1.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000135124 ; ENSMUSP00000117505 ; ENSMUSG00000020456 .

    Organism-specific databases

    MGIi MGI:1098267. Ogdh.

    Phylogenomic databases

    GeneTreei ENSGT00530000063092.
    InParanoidi Q5SVY1.

    Miscellaneous databases

    ChiTaRSi OGDH. mouse.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q5SVY1.

    Family and domain databases

    InterProi IPR011603. 2oxoglutarate_DH_E1.
    [Graphical view ]
    PANTHERi PTHR23152. PTHR23152. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    3. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
      Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
      Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiQ5SVY1_MOUSE
    AccessioniPrimary (citable) accession number: Q5SVY1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 21, 2004
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3