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Q5SVY0

- Q5SVY0_MOUSE

UniProt

Q5SVY0 - Q5SVY0_MOUSE

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Protein
Submitted name: 2-oxoglutarate dehydrogenase, mitochondrial
Gene
Ogdh
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. oxoglutarate dehydrogenase (NAD+) activity Source: MGI
  2. oxoglutarate dehydrogenase (succinyl-transferring) activity Source: InterPro
  3. thiamine pyrophosphate binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. 2-oxoglutarate metabolic process Source: Ensembl
  2. NADH metabolic process Source: Ensembl
  3. succinyl-CoA metabolic process Source: Ensembl
  4. tricarboxylic acid cycle Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
2-oxoglutarate dehydrogenase, mitochondrialImported
Gene namesi
Name:OgdhImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:1098267. Ogdh.

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: MGI
  2. oxoglutarate dehydrogenase complex Source: Ensembl
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ5SVY0.

Expressioni

Gene expression databases

ArrayExpressiQ5SVY0.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00530000063092.
HOGENOMiHOG000259586.
HOVERGENiHBG094366.
InParanoidiQ5SVY0.

Family and domain databases

InterProiIPR011603. 2oxoglutarate_DH_E1.
[Graphical view]
PANTHERiPTHR23152. PTHR23152. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5SVY0-1 [UniParc]FASTAAdd to Basket

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MFHLRTCAAK LRPLTASQTV KTFSQNKPAA IRTFQQIRCY SAPVAAEPFL    50
SGTSSNYVEE MYCAWLENPK SVHKSWDIFF RNTNAGAPPG TAYQSPLSLS 100
RSSLATMAHA QSLVEAQPNV DKL 123
Length:123
Mass (Da):13,581
Last modified:December 21, 2004 - v1
Checksum:iF734C5EC9E9ABD94
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei123 – 1231Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL607152 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000140765; ENSMUSP00000117323; ENSMUSG00000020456.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL607152 Genomic DNA. No translation available.

3D structure databases

ModBasei Search...

Proteomic databases

PRIDEi Q5SVY0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000140765 ; ENSMUSP00000117323 ; ENSMUSG00000020456 .

Organism-specific databases

MGIi MGI:1098267. Ogdh.

Phylogenomic databases

GeneTreei ENSGT00530000063092.
HOGENOMi HOG000259586.
HOVERGENi HBG094366.
InParanoidi Q5SVY0.

Miscellaneous databases

ChiTaRSi OGDH. mouse.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q5SVY0.

Family and domain databases

InterProi IPR011603. 2oxoglutarate_DH_E1.
[Graphical view ]
PANTHERi PTHR23152. PTHR23152. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  3. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiQ5SVY0_MOUSE
AccessioniPrimary (citable) accession number: Q5SVY0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: May 14, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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