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Protein

C-C motif chemokine

Gene

Ccl2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionCytokineUniRule annotationSAAS annotation
Biological processChemotaxisUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
C-C motif chemokineUniRule annotation
Gene namesi
Name:Ccl2Imported
ORF Names:mCG_8184Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98259 Ccl2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23UniRule annotationAdd BLAST23
ChainiPRO_501420590224 – 148C-C motif chemokineUniRule annotationAdd BLAST125

Expressioni

Gene expression databases

BgeeiENSMUSG00000035385
ExpressionAtlasiQ5SVU3 baseline and differential

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ5SVU3
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 90SCYInterPro annotationAdd BLAST60

Sequence similaritiesi

Belongs to the intercrine beta (chemokine CC) family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation

Phylogenomic databases

eggNOGiENOG410J1ST Eukaryota
ENOG410YXJU LUCA
HOVERGENiHBG017871
KOiK14624
OMAiNAPLTCC
OrthoDBiEOG091G14KV

Family and domain databases

InterProiView protein in InterPro
IPR000827 Chemokine_CC_CS
IPR001811 Chemokine_IL8-like_dom
IPR036048 Interleukin_8-like_sf
PfamiView protein in Pfam
PF00048 IL8, 1 hit
SMARTiView protein in SMART
SM00199 SCY, 1 hit
SUPFAMiSSF54117 SSF54117, 1 hit
PROSITEiView protein in PROSITE
PS00472 SMALL_CYTOKINES_CC, 1 hit

Sequencei

Sequence statusi: Complete.

Q5SVU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQVPVMLLGL LFTVAGWSIH VLAQPDAVNA PLTCCYSFTS KMIPMSRLES
60 70 80 90 100
YKRITSSRCP KEAVVFVTKL KREVCADPKK EWVQTYIKNL DRNQMRSEPT
110 120 130 140
TLFKTASALR SSAPLNVKLT RKSEANASTT FSTTTSSTSV GVTSVTVN
Length:148
Mass (Da):16,326
Last modified:May 10, 2005 - v1
Checksum:i29A5505FC6D94837
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC145867 mRNA Translation: AAI45868.1
BC145869 mRNA Translation: AAI45870.1
AK132590 mRNA Translation: BAE21250.1
AK150937 mRNA Translation: BAE29972.1
AK153468 mRNA Translation: BAE32019.1
CT010187 mRNA Translation: CAJ18395.1
CH466556 Genomic DNA Translation: EDL15657.1
RefSeqiNP_035463.1, NM_011333.3
UniGeneiMm.290320

Genome annotation databases

GeneIDi20296
KEGGimmu:20296

Similar proteinsi

Entry informationi

Entry nameiQ5SVU3_MOUSE
AccessioniPrimary (citable) accession number: Q5SVU3
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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