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Protein
Submitted name:

Caspase-7

Gene

CASP7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protease, Thiol proteaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Caspase-7Imported
Gene namesi
Name:CASP7Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000165806.19
HGNCiHGNC:1508 CASP7

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000165806

PTM / Processingi

Proteomic databases

MaxQBiQ5SVL2
PeptideAtlasiQ5SVL2
PRIDEiQ5SVL2

Expressioni

Gene expression databases

BgeeiENSG00000165806
ExpressionAtlasiQ5SVL2 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5SVL2
SMRiQ5SVL2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini66 – 190CASPASE_P20InterPro annotationAdd BLAST125

Sequence similaritiesi

Belongs to the peptidase C14A family.SAAS annotation

Phylogenomic databases

eggNOGiKOG3573 Eukaryota
ENOG410ZQIE LUCA
GeneTreeiENSGT00760000118912
HOGENOMiHOG000231878
HOVERGENiHBG050802

Family and domain databases

CDDicd00032 CASc, 1 hit
InterProiView protein in InterPro
IPR029030 Caspase-like_dom_sf
IPR033139 Caspase_cys_AS
IPR016129 Caspase_his_AS
IPR001309 Pept_C14_p20
IPR015917 Pept_C14A
PRINTSiPR00376 IL1BCENZYME
SMARTiView protein in SMART
SM00115 CASc, 1 hit
SUPFAMiSSF52129 SSF52129, 1 hit
PROSITEiView protein in PROSITE
PS01122 CASPASE_CYS, 1 hit
PS01121 CASPASE_HIS, 1 hit
PS50208 CASPASE_P20, 1 hit

Sequencei

Sequence statusi: Fragment.

Q5SVL2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADDQGCIEE QGVEDSANED SVDAKPDRSS FVPSLFSKKK KNVTMRSIKT
60 70 80 90 100
TRDRVPTYQY NMNFEKLGKC IIINNKNFDK VTGMGVRNGT DKDAEALFKC
110 120 130 140 150
FRSLGFDVIV YNDCSCAKMQ DLLKKASEED HTNAACFACI LLSHGEENVI
160 170 180 190 200
YGKDGVTPIK DLTAHFRGDR CKTLLEKPKL FFIQACRGTE LDDGIQADSG
210 220
PINDTDANPR YKIPVEADFL FA
Length:222
Mass (Da):24,790
Last modified:December 21, 2004 - v1
Checksum:i752B053E5870BB91
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei222Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL592546 Genomic DNA No translation available.
AL627395 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000429617; ENSP00000400094; ENSG00000165806
UCSCiuc057wbr.1 human

Similar proteinsi

Entry informationi

Entry nameiQ5SVL2_HUMAN
AccessioniPrimary (citable) accession number: Q5SVL2
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: April 25, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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