Q5SVI3 (Q5SVI3_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Calcium/calmodulin-dependent protein kinase II, beta EMBL CAI25259.1

Submitted name:
Uncharacterized protein Ensembl ENSMUSP00000099119

Gene names

Name:	Camk2b MGI 88257 Ensembl ENSMUSP00000099119
Synonyms:	Camk2g MGI 88259
ORF Names:	RP23-340E18.5-004 EMBL CAI25259.1

Organism

Mus musculus (Mouse) EMBL CAI25259.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	518 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 protein kinase domain. SAAS SAAS020636

Ontologies

Keywords
Ligand	ATP-binding SAAS SAAS020636 RuleBase RU000304 Nucleotide-binding
Molecular function	Kinase Serine/threonine-protein kinase SAAS SAAS020636 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	G1/S transition of mitotic cell cycle Inferred from mutant phenotype. Source: MGI activation of meiosis involved in egg activation Inferred from mutant phenotype. Source: MGI calcium ion transport Inferred from mutant phenotype. Source: MGI induction of apoptosis in response to chemical stimulus Inferred from direct assay. Source: MGI inhibitory G-protein coupled receptor phosphorylation Inferred from direct assay. Source: MGI neuromuscular process controlling balance Inferred from mutant phenotype. Source: MGI peptidyl-serine phosphorylation Inferred from direct assay. Source: MGI protein autophosphorylation Inferred from mutant phenotype. Source: MGI regulation of long-term neuronal synaptic plasticity Inferred from mutant phenotype. Source: MGI regulation of synaptic transmission, cholinergic Inferred from mutant phenotype. Source: MGI response to cadmium ion Inferred from direct assay. Source: MGI
Cellular component	cytosol Inferred from direct assay. Source: MGI spindle midzone Inferred from direct assay. Source: MGI
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW calmodulin binding Inferred from electronic annotation. Source: InterPro calmodulin-dependent protein kinase activity Inferred from direct assay. Source: MGI
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5SVI3 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 89898B59FFB0B213	FASTA	518	58,111
	10 20 30 40 50 60 MATTVTCTRF TDEYQLYEDI GKGAFSVVRR CVKLCTGHEY AAKIINTKKL SARDHQKLER 70 80 90 100 110 120 EARICRLLKH SNIVRLHDSI SEEGFHYLVF DLVTGGELFE DIVAREYYSE ADASHCIQQI 130 140 150 160 170 180 LEAVLHCHQM GVVHRDLKPE NLLLASKCKG AAVKLADFGL AIEVQGDQQA WFGFAGTPGY 190 200 210 220 230 240 LSPEVLRKEA YGKPVDIWAC GVILYILLVG YPPFWDEDQH KLYQQIKAGA YDFPSPEWDT 250 260 270 280 290 300 VTPEAKNLIN QMLTINPAKR ITAHEALKHP WVCQRSTVAS MMHRQETVEC LKKFNARRKL 310 320 330 340 350 360 KGAILTTMLA TRNFSVGRQT TAPATMSTAA SGTTMGLVEQ AKSLLNKKAD GVKEPQTTVI 370 380 390 400 410 420 HNPVDGIKES SDSTNTTIED EDAKARKQEI IKTTEQLIEA VNNGDFEAYA KICDPGLTSF 430 440 450 460 470 480 EPEALGNLVE GMDFHRFYFE NLLAKNSKPI HTTILNPHVH VIGEDAACIA YIRLTQYIDG 490 500 510 QGRPRTSQSE ETRVWHRRDG KWQNVHFHCS GAPVAPLQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Mouse Genome Sequencing Consortium Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed: 19468303] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6 Ensembl ENSMUSP00000099119.
[2]	Howden P. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Collins J. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Ensembl Submitted (JUN-2011) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000099119.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AL611926, AL645469 Genomic DNA. Translation: CAI24949.1. AL645469, AL611926 Genomic DNA. Translation: CAI25259.1.
IPI	IPI00624499.
UniGene	Mm.439733.
3D structure databases
ProteinModelPortal	Q5SVI3.
SMR	Q5SVI3. Positions 8-514.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q5SVI3. 1 interaction.
STRING	Q5SVI3.
Proteomic databases
PRIDE	Q5SVI3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000101585; ENSMUSP00000099119; ENSMUSG00000057897.
Organism-specific databases
MGI	MGI:88257. Camk2b.
Phylogenomic databases
GeneTree	ENSGT00550000074354.
HOVERGEN	HBG108055.
PhylomeDB	Q5SVI3.
Gene expression databases
ArrayExpress	Q5SVI3.
Bgee	Q5SVI3.
Genevestigator	Q5SVI3.
Family and domain databases
InterPro	IPR020636. Ca/CaM-dep_Ca-dep_prot_Kinase. IPR013543. Ca/CaM-dep_prot_kinase-assoc. IPR011009. Kinase-like_dom. IPR000719. Prot_kinase_cat_dom. IPR017441. Protein_kinase_ATP_BS. IPR017442. Se/Thr_kinase-like_dom. IPR008271. Ser/Thr_kinase_AS. IPR002290. Ser/Thr_kinase_dom. [Graphical view]
PANTHER	PTHR24347. PTHR24347. 1 hit.
Pfam	PF08332. CaMKII_AD. 1 hit. PF00069. Pkinase. 1 hit. [Graphical view]
SMART	SM00220. S_TKc. 1 hit. [Graphical view]
SUPFAM	SSF56112. Kinase_like. 1 hit.
PROSITE	PS00107. PROTEIN_KINASE_ATP. 1 hit. PS50011. PROTEIN_KINASE_DOM. 1 hit. PS00108. PROTEIN_KINASE_ST. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q5SVI3_MOUSE

Accession

Primary (citable) accession number: Q5SVI3

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	January 25, 2012
This is version 74 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)