Unreviewed, UniProtKB/TrEMBL Q5SV01 (Q5SV01_MOUSE)

Names and origin

Protein names

Submitted name:
    Interleukin 5 EMBL CAI24692.2

Gene names

Name:	Il5 MGI 96557
ORF Names:	RP23-239O19.2-001 EMBL CAI24692.2, mCG_13786 EMBL EDL33573.1

Organism

Mus musculus (Mouse) EMBL CAI24692.2

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	133 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

Ontologies

Gene Ontology (GO)
Biological process	cytokine-mediated signaling pathway Inferred from electronic annotation. Source: Compara immune response Inferred from electronic annotation. Source: InterPro inflammatory response Inferred from electronic annotation. Source: Compara positive regulation of B cell proliferation Inferred from electronic annotation. Source: Compara positive regulation of JAK-STAT cascade Inferred from electronic annotation. Source: Compara positive regulation of eosinophil differentiation Inferred from electronic annotation. Source: Compara
Cellular component	extracellular region Inferred from electronic annotation. Source: InterPro soluble fraction Inferred from electronic annotation. Source: Compara
Molecular function	growth factor activity Inferred from electronic annotation. Source: InterPro interleukin-5 receptor binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5SV01-1 [UniParc]. Last modified February 20, 2007. Version 2. Checksum: C6DC091682452AF4	FASTA	133	15,410
	10 20 30 40 50 60 MRRMLLHLSV LTLSCVWATA MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ 70 80 90 100 110 120 LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE 130 FLGVMSTEWA MEG

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	Dunn M. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain EMBL AAI32067.1.
[3]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed: 12040188] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL33573.1.
[4]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL33573.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BC125366 mRNA. Translation: AAI25367.1. BC132066 mRNA. Translation: AAI32067.1. AL645741 Genomic DNA. Translation: CAI24692.2. CH466575 Genomic DNA. Translation: EDL33573.1.
IPI	IPI00115757.
RefSeq	NP_034688.1.
UniGene	Mm.4461
3D structure databases
SMR	Q5SV01. Positions 23-129.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5SV01.
Proteomic databases
PRIDE	Q5SV01.
Genome annotation databases
Ensembl	ENSMUST00000048605; ENSMUSP00000043369; ENSMUSG00000036117; Mus musculus. [Genome view]
GeneID	16191.
KEGG	mmu:16191.
Organism-specific databases
CTD	16191.
MGI	MGI:96557. Il5.
Phylogenomic databases
HOVERGEN	Q5SV01.
InParanoid	Q5SV01.
OMA	EVFQGID.
PhylomeDB	Q5SV01.
Gene expression databases
ArrayExpress	Q5SV01.
Bgee	Q5SV01.
Genevestigator	Q5SV01.
Family and domain databases
InterPro	IPR009079. 4_helix_cytokine-like_core. IPR000186. Interleukin_5. [Graphical view]
PANTHER	PTHR10525. Interleukin_5. 1 hit.
Pfam	PF02025. IL5. 1 hit. [Graphical view]
PRINTS	PR00432. INTERLEUKIN5.
ProDom	PD006721. Interleukin_5. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...
Other Resources
NextBio	289101.
SOURCE	Search...

Entry information

Entry name

Q5SV01_MOUSE

Accession

Primary (citable) accession number: Q5SV01
Secondary accession number(s): Q05A89

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	February 20, 2007
Last modified:	February 9, 2010
This is version 45 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)