Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Interferon regulatory factor 4

Gene

Irf4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Interferon regulatory factor 4Imported
Submitted name:
Interferon regulatory factor 4, isoform CRA_bImported
Gene namesi
Name:Irf4Imported
ORF Names:mCG_4922Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1096873. Irf4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000021356.

Structurei

3D structure databases

SMRiQ5SUZ4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini21 – 129IRF tryptophan pentad repeatInterPro annotationAdd BLAST109

Sequence similaritiesi

Belongs to the IRF family.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410IES5. Eukaryota.
ENOG411023V. LUCA.
HOVERGENiHBG003072.
KOiK09445.
OMAiSDCRLHI.
OrthoDBiEOG091G067P.

Family and domain databases

CDDicd00103. IRF. 1 hit.
Gene3Di1.10.10.10. 1 hit.
2.60.200.10. 1 hit.
InterProiView protein in InterPro
IPR019817. Interferon_reg_fac_CS.
IPR001346. Interferon_reg_fact_DNA-bd_dom.
IPR019471. Interferon_reg_factor-3.
IPR017855. SMAD_dom-like.
IPR008984. SMAD_FHA_domain.
IPR011991. WHTH_DNA-bd_dom.
PANTHERiPTHR11949. PTHR11949. 1 hit.
PfamiView protein in Pfam
PF00605. IRF. 1 hit.
PF10401. IRF-3. 1 hit.
PRINTSiPR00267. INTFRNREGFCT.
SMARTiView protein in SMART
SM00348. IRF. 1 hit.
SM01243. IRF-3. 1 hit.
SUPFAMiSSF46785. SSF46785. 1 hit.
SSF49879. SSF49879. 1 hit.
PROSITEiView protein in PROSITE
PS00601. IRF_1. 1 hit.
PS51507. IRF_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5SUZ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNLETGSRGS EFGMSAVSCG NGKLRQWLID QIDSGKYPGL VWENEEKSVF
60 70 80 90 100
RIPWKHAGKQ DYNREEDAAL FKAWALFKGK FREGIDKPDP PTWKTRLRCA
110 120 130 140 150
LNKSNDFEEL VERSQLDISD PYKVYRIVPE GAKKGAKQLT LDDTQMAMGH
160 170 180 190 200
PYPMTAPYGS LPAQQVHNYM MPPHDRSWRD YAPDQSHPEI PYQCPVTFGP
210 220 230 240 250
RGHHWQGPSC ENGCQVTGTF YACAPPESQA PGIPIEPSIR SAEALALSDC
260 270 280 290 300
RLHICLYYRD ILVKELTTTS PEGCRISHGH TYDVSNLDQV LFPYPDDNGQ
310 320 330 340 350
RKNIEKLLSH LERGLVLWMA PDGLYAKRLC QSRIYWDGPL ALCSDRPNKL
360 370 380 390 400
ERDQTCKLFD TQQFLSELQV FAHHGRPAPR FQVTLCFGEE FPDPQRQRKL
410 420 430 440 450
ITAHVEPLLA RQLYYFAQQN TGHFLRGYEL PEHVTTPDYH RSLRHSSIQE
Length:450
Mass (Da):51,577
Last modified:May 10, 2005 - v1
Checksum:i5FD94CA6C453869C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC137713 mRNA. Translation: AAI37714.1.
BC137714 mRNA. Translation: AAI37715.1.
AK089819 mRNA. Translation: BAC40969.1.
AK154315 mRNA. Translation: BAE32509.1.
CH466561 Genomic DNA. Translation: EDL32379.1.
RefSeqiNP_038702.1. NM_013674.2.
UniGeneiMm.4677.

Genome annotation databases

GeneIDi16364.
KEGGimmu:16364.

Similar proteinsi

Entry informationi

Entry nameiQ5SUZ4_MOUSE
AccessioniPrimary (citable) accession number: Q5SUZ4
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation