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Q5SUV9

- Q5SUV9_MOUSE

UniProt

Q5SUV9 - Q5SUV9_MOUSE

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Protein
Submitted name: Aromatic-L-amino-acid decarboxylase
Gene
Ddc
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Cofactori

Pyridoxal phosphate By similarity.UniRule annotation

GO - Molecular functioni

  1. amino acid binding Source: Ensembl
  2. aromatic-L-amino-acid decarboxylase activity Source: MGI
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. cellular amino acid metabolic process Source: InterPro
  2. cellular response to alkaloid Source: Ensembl
  3. cellular response to drug Source: Ensembl
  4. cellular response to growth factor stimulus Source: Ensembl
  5. circadian rhythm Source: Ensembl
  6. isoquinoline alkaloid metabolic process Source: Ensembl
  7. multicellular organismal aging Source: Ensembl
  8. phytoalexin metabolic process Source: Ensembl
  9. response to pyrethroid Source: Ensembl
  10. response to toxic substance Source: MGI
  11. serotonin biosynthetic process Source: Ensembl
  12. synaptic vesicle amine transport Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aromatic-L-amino-acid decarboxylaseImported
Gene namesi
Name:DdcImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:94876. Ddc.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: Ensembl
  2. cytoplasm Source: MGI
  3. neuronal cell body Source: Ensembl
  4. synaptic vesicle Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ArrayExpressiQ5SUV9.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000105286.

Structurei

3D structure databases

ProteinModelPortaliQ5SUV9.
SMRiQ5SUV9. Positions 1-253.

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00730000110825.
HOGENOMiHOG000121941.
HOVERGENiHBG000944.
InParanoidiQ5SUV9.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010977. Aromatic_deC.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
PRINTSiPR00800. YHDCRBOXLASE.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5SUV9-1 [UniParc]FASTAAdd to Basket

« Hide

MDSREFRRRG KEMVDYIADY LDGIEGRPVY PDVEPGYLRP LIPATAPQEP    50
ETYEDIIKDI EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC 100
IGFSWAASPA CTELETVMMD WLGKMLELPE AFLAGRAGEG GGVIQGSASE 150
ATLVALLAAR TKVIRQLQAA SPEFTQAAIM EKLVAYTSDQ AHSSVERAGL 200
IGGIKLKAVP SDGNFSMRAS ALREALERDK AAGLIPFFVV ATLGTTSCCS 250
FDN 253
Length:253
Mass (Da):27,401
Last modified:December 21, 2004 - v1
Checksum:i1509ED6DE6E8B259
GO

Non-terminal residue

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei253 – 2531Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596450 Genomic DNA. No translation available.
AL645803 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000155690; ENSMUSP00000121096; ENSMUSG00000020182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596450 Genomic DNA. No translation available.
AL645803 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali Q5SUV9.
SMRi Q5SUV9. Positions 1-253.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000105286.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000155690 ; ENSMUSP00000121096 ; ENSMUSG00000020182 .

Organism-specific databases

MGIi MGI:94876. Ddc.

Phylogenomic databases

GeneTreei ENSGT00730000110825.
HOGENOMi HOG000121941.
HOVERGENi HBG000944.
InParanoidi Q5SUV9.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ArrayExpressi Q5SUV9.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010977. Aromatic_deC.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
PRINTSi PR00800. YHDCRBOXLASE.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ5SUV9_MOUSE
AccessioniPrimary (citable) accession number: Q5SUV9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: July 9, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi