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Q5SUV9

- Q5SUV9_MOUSE

UniProt

Q5SUV9 - Q5SUV9_MOUSE

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Protein
Submitted name:

Aromatic-L-amino-acid decarboxylase

Gene

Ddc

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Cofactori

Note: Pyridoxal phosphate.UniRule annotation

GO - Molecular functioni

  1. amino acid binding Source: Ensembl
  2. aromatic-L-amino-acid decarboxylase activity Source: MGI
  3. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. cellular amino acid metabolic process Source: InterPro
  2. cellular response to alkaloid Source: Ensembl
  3. cellular response to drug Source: Ensembl
  4. cellular response to growth factor stimulus Source: Ensembl
  5. circadian rhythm Source: Ensembl
  6. isoquinoline alkaloid metabolic process Source: Ensembl
  7. multicellular organismal aging Source: Ensembl
  8. phytoalexin metabolic process Source: Ensembl
  9. response to pyrethroid Source: Ensembl
  10. response to toxic substance Source: MGI
  11. serotonin biosynthetic process Source: Ensembl
  12. synaptic vesicle amine transport Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

LyaseUniRule annotation

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Aromatic-L-amino-acid decarboxylaseImported
Gene namesi
Name:DdcImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:94876. Ddc.

Subcellular locationi

GO - Cellular componenti

  1. axon Source: Ensembl
  2. cytoplasm Source: MGI
  3. extracellular vesicular exosome Source: Ensembl
  4. neuronal cell body Source: Ensembl
  5. synaptic vesicle Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ5SUV9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000105286.

Structurei

3D structure databases

ProteinModelPortaliQ5SUV9.
SMRiQ5SUV9. Positions 1-253.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119205.
HOGENOMiHOG000121941.
HOVERGENiHBG000944.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010977. Aromatic_deC.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
PRINTSiPR00800. YHDCRBOXLASE.
SUPFAMiSSF53383. SSF53383. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q5SUV9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDSREFRRRG KEMVDYIADY LDGIEGRPVY PDVEPGYLRP LIPATAPQEP
60 70 80 90 100
ETYEDIIKDI EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC
110 120 130 140 150
IGFSWAASPA CTELETVMMD WLGKMLELPE AFLAGRAGEG GGVIQGSASE
160 170 180 190 200
ATLVALLAAR TKVIRQLQAA SPEFTQAAIM EKLVAYTSDQ AHSSVERAGL
210 220 230 240 250
IGGIKLKAVP SDGNFSMRAS ALREALERDK AAGLIPFFVV ATLGTTSCCS

FDN
Length:253
Mass (Da):27,401
Last modified:December 21, 2004 - v1
Checksum:i1509ED6DE6E8B259
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei253 – 2531Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596450 Genomic DNA. No translation available.
AL645803 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENSMUST00000155690; ENSMUSP00000121096; ENSMUSG00000020182.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596450 Genomic DNA. No translation available.
AL645803 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortali Q5SUV9.
SMRi Q5SUV9. Positions 1-253.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000105286.

Chemistry

BindingDBi Q5SUV9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000155690 ; ENSMUSP00000121096 ; ENSMUSG00000020182 .

Organism-specific databases

MGIi MGI:94876. Ddc.

Phylogenomic databases

GeneTreei ENSGT00760000119205.
HOGENOMi HOG000121941.
HOVERGENi HBG000944.

Miscellaneous databases

ChiTaRSi Ddc. mouse.
SOURCEi Search...

Gene expression databases

ExpressionAtlasi Q5SUV9. baseline and differential.

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
InterProi IPR010977. Aromatic_deC.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view ]
Pfami PF00282. Pyridoxal_deC. 1 hit.
[Graphical view ]
PRINTSi PR00800. YHDCRBOXLASE.
SUPFAMi SSF53383. SSF53383. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ5SUV9_MOUSE
AccessioniPrimary (citable) accession number: Q5SUV9
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 26, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3