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Q5SUV8

- Q5SUV8_MOUSE

UniProt

Q5SUV8 - Q5SUV8_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Ddc

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 92 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    Cofactori

    Pyridoxal phosphate.UniRule annotation

    GO - Molecular functioni

    1. amino acid binding Source: Ensembl
    2. aromatic-L-amino-acid decarboxylase activity Source: MGI
    3. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. cellular amino acid metabolic process Source: InterPro
    2. cellular response to alkaloid Source: Ensembl
    3. cellular response to drug Source: Ensembl
    4. cellular response to growth factor stimulus Source: Ensembl
    5. circadian rhythm Source: Ensembl
    6. isoquinoline alkaloid metabolic process Source: Ensembl
    7. multicellular organismal aging Source: Ensembl
    8. phytoalexin metabolic process Source: Ensembl
    9. response to pyrethroid Source: Ensembl
    10. response to toxic substance Source: MGI
    11. serotonin biosynthetic process Source: Ensembl
    12. synaptic vesicle amine transport Source: Ensembl

    Keywords - Molecular functioni

    LyaseUniRule annotation

    Keywords - Ligandi

    Pyridoxal phosphateUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:DdcImported
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:94876. Ddc.

    Subcellular locationi

    GO - Cellular componenti

    1. axon Source: Ensembl
    2. cytoplasm Source: MGI
    3. neuronal cell body Source: Ensembl
    4. synaptic vesicle Source: Ensembl

    PTM / Processingi

    Proteomic databases

    PRIDEiQ5SUV8.

    Expressioni

    Gene expression databases

    ArrayExpressiQ5SUV8.
    GenevestigatoriQ5SUV8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5SUV8.
    SMRiQ5SUV8. Positions 1-475.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.UniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00730000110825.
    HOVERGENiHBG000944.
    InParanoidiQ5SUV8.
    KOiK01593.
    OMAiPICNKED.
    PhylomeDBiQ5SUV8.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProiIPR010977. Aromatic_deC.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view]
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    PRINTSiPR00800. YHDCRBOXLASE.
    SUPFAMiSSF53383. SSF53383. 1 hit.
    PROSITEiPS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5SUV8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDSREFRRRG KEMVDYIADY LDGIEGRPVY PDVEPGYLRP LIPATAPQEP    50
    ETYEDIIKDI EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC 100
    IGFSWAASPA CTELETVMMD WLGKMLELPE AFLAGRAGEG GGVIQGSASE 150
    ATLVALLAAR TKVIRQLQAA SPEFTQAAIM EKLVAYTSDQ AHSSVERAGL 200
    IGGIKLKAVP SDGNFSMRAS ALREALERDK AAGLIPFFVV ATLGTTSCCS 250
    FDNLLEVGPI CNQEGVWLHI DAAYAGSAFI CPEFRYLLNG VEFADSFNFN 300
    PHKWLLVNFD CSAMWVKRRT DLTGAFNMDP VYLKHSHQDS GFITDYRHWQ 350
    IPLGRRFRSL KMWFVFRMYG VKGLQAYIRK HVELSHEFES LVRQDPRFEI 400
    CTEVILGLVC FRLKGSNELN ETLLQRINSA KKIHLVPCRL RDKFVLRFAV 450
    CARTVESAHV QLAWEHISDL ASSVLRAEKE 480
    Length:480
    Mass (Da):53,874
    Last modified:May 10, 2005 - v1
    Checksum:iD6C1CA504AC2D10E
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK149141 mRNA. Translation: BAE28750.1.
    RefSeqiNP_001177377.1. NM_001190448.1.
    NP_057881.1. NM_016672.4.
    XP_006514550.1. XM_006514487.1.
    XP_006514551.1. XM_006514488.1.
    XP_006514552.1. XM_006514489.1.
    XP_006514553.1. XM_006514490.1.
    UniGeneiMm.12906.

    Genome annotation databases

    GeneIDi13195.
    KEGGimmu:13195.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK149141 mRNA. Translation: BAE28750.1 .
    RefSeqi NP_001177377.1. NM_001190448.1.
    NP_057881.1. NM_016672.4.
    XP_006514550.1. XM_006514487.1.
    XP_006514551.1. XM_006514488.1.
    XP_006514552.1. XM_006514489.1.
    XP_006514553.1. XM_006514490.1.
    UniGenei Mm.12906.

    3D structure databases

    ProteinModelPortali Q5SUV8.
    SMRi Q5SUV8. Positions 1-475.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q5SUV8.

    Protocols and materials databases

    DNASUi 13195.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 13195.
    KEGGi mmu:13195.

    Organism-specific databases

    CTDi 1644.
    MGIi MGI:94876. Ddc.

    Phylogenomic databases

    GeneTreei ENSGT00730000110825.
    HOVERGENi HBG000944.
    InParanoidi Q5SUV8.
    KOi K01593.
    OMAi PICNKED.
    PhylomeDBi Q5SUV8.

    Miscellaneous databases

    NextBioi 283324.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q5SUV8.
    Genevestigatori Q5SUV8.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    3.90.1150.10. 1 hit.
    InterProi IPR010977. Aromatic_deC.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    IPR015422. PyrdxlP-dep_Trfase_major_sub2.
    IPR021115. Pyridoxal-P_BS.
    [Graphical view ]
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    PRINTSi PR00800. YHDCRBOXLASE.
    SUPFAMi SSF53383. SSF53383. 1 hit.
    PROSITEi PS00392. DDC_GAD_HDC_YDC. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    4. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    5. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    6. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Sympathetic ganglionImported.

    Entry informationi

    Entry nameiQ5SUV8_MOUSE
    AccessioniPrimary (citable) accession number: Q5SUV8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 10, 2005
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 92 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)