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Q5SUV8 (Q5SUV8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified July 9, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Ddc MGI 94876
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length480 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Cofactor

Pyridoxal phosphate By similarity. RuleBase RU000382

Sequence similarities

Belongs to the group II decarboxylase family. RuleBase RU000382

Ontologies

Keywords
   LigandPyridoxal phosphate RuleBase RU000382
   Molecular functionLyase RuleBase RU000382
Gene Ontology (GO)
   Biological_processcellular amino acid metabolic process

Inferred from electronic annotation. Source: InterPro

cellular response to alkaloid

Inferred from electronic annotation. Source: Ensembl

cellular response to drug

Inferred from electronic annotation. Source: Ensembl

cellular response to growth factor stimulus

Inferred from electronic annotation. Source: Ensembl

circadian rhythm

Inferred from electronic annotation. Source: Ensembl

isoquinoline alkaloid metabolic process

Inferred from electronic annotation. Source: Ensembl

multicellular organismal aging

Inferred from electronic annotation. Source: Ensembl

phytoalexin metabolic process

Inferred from electronic annotation. Source: Ensembl

response to pyrethroid

Inferred from electronic annotation. Source: Ensembl

response to toxic substance

Inferred from direct assay PubMed 7904615. Source: MGI

serotonin biosynthetic process

Inferred from electronic annotation. Source: Ensembl

synaptic vesicle amine transport

Inferred from electronic annotation. Source: Ensembl

   Cellular_componentaxon

Inferred from electronic annotation. Source: Ensembl

cytoplasm

Inferred from direct assay PubMed 23010799. Source: MGI

neuronal cell body

Inferred from electronic annotation. Source: Ensembl

synaptic vesicle

Inferred from electronic annotation. Source: Ensembl

   Molecular_functionamino acid binding

Inferred from electronic annotation. Source: Ensembl

aromatic-L-amino-acid decarboxylase activity

Inferred from direct assay PubMed 23863468. Source: MGI

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q5SUV8 [UniParc].

Last modified May 10, 2005. Version 1.
Checksum: D6C1CA504AC2D10E

FASTA48053,874
        10         20         30         40         50         60 
MDSREFRRRG KEMVDYIADY LDGIEGRPVY PDVEPGYLRP LIPATAPQEP ETYEDIIKDI 

        70         80         90        100        110        120 
EKIIMPGVTH WHSPYFFAYF PTASSYPAML ADMLCGAIGC IGFSWAASPA CTELETVMMD 

       130        140        150        160        170        180 
WLGKMLELPE AFLAGRAGEG GGVIQGSASE ATLVALLAAR TKVIRQLQAA SPEFTQAAIM 

       190        200        210        220        230        240 
EKLVAYTSDQ AHSSVERAGL IGGIKLKAVP SDGNFSMRAS ALREALERDK AAGLIPFFVV 

       250        260        270        280        290        300 
ATLGTTSCCS FDNLLEVGPI CNQEGVWLHI DAAYAGSAFI CPEFRYLLNG VEFADSFNFN 

       310        320        330        340        350        360 
PHKWLLVNFD CSAMWVKRRT DLTGAFNMDP VYLKHSHQDS GFITDYRHWQ IPLGRRFRSL 

       370        380        390        400        410        420 
KMWFVFRMYG VKGLQAYIRK HVELSHEFES LVRQDPRFEI CTEVILGLVC FRLKGSNELN 

       430        440        450        460        470        480 
ETLLQRINSA KKIHLVPCRL RDKFVLRFAV CARTVESAHV QLAWEHISDL ASSVLRAEKE 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE28750.1.
Tissue: Sympathetic ganglion EMBL BAE28750.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE28750.1.
Tissue: Sympathetic ganglion EMBL BAE28750.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE28750.1.
Tissue: Sympathetic ganglion EMBL BAE28750.1.
[4]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE28750.1.
Tissue: Sympathetic ganglion EMBL BAE28750.1.
[5]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE28750.1.
Tissue: Sympathetic ganglion EMBL BAE28750.1.
[6]Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., Nishiyori H. expand/collapse author list , Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., Muramatsu M., Hayashizaki Y.
Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE28750.1.
Tissue: Sympathetic ganglion EMBL BAE28750.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE28750.1.
Tissue: Sympathetic ganglion EMBL BAE28750.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAE28750.1.
Tissue: Sympathetic ganglion EMBL BAE28750.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK149141 mRNA. Translation: BAE28750.1.
RefSeqNP_001177377.1. NM_001190448.1.
NP_057881.1. NM_016672.4.
XP_006514550.1. XM_006514487.1.
XP_006514551.1. XM_006514488.1.
XP_006514552.1. XM_006514489.1.
XP_006514553.1. XM_006514490.1.
UniGeneMm.12906.

3D structure databases

ProteinModelPortalQ5SUV8.
SMRQ5SUV8. Positions 1-475.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ5SUV8.

Protocols and materials databases

DNASU13195.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID13195.
KEGGmmu:13195.

Organism-specific databases

CTD1644.
MGIMGI:94876. Ddc.

Phylogenomic databases

GeneTreeENSGT00730000110825.
HOVERGENHBG000944.
InParanoidQ5SUV8.
KOK01593.
OMAPICNKED.
PhylomeDBQ5SUV8.

Gene expression databases

ArrayExpressQ5SUV8.
GenevestigatorQ5SUV8.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProIPR010977. Aromatic_deC.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
IPR021115. Pyridoxal-P_BS.
[Graphical view]
PfamPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
PRINTSPR00800. YHDCRBOXLASE.
SUPFAMSSF53383. SSF53383. 1 hit.
PROSITEPS00392. DDC_GAD_HDC_YDC. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio283324.
SOURCESearch...

Entry information

Entry nameQ5SUV8_MOUSE
AccessionPrimary (citable) accession number: Q5SUV8
Entry history
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: July 9, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)