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Protein
Submitted name:

RNA-binding protein EWS

Gene

Ewsr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
RNA-binding protein EWSImported
Gene namesi
Name:Ewsr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:99960. Ewsr1.

PTM / Processingi

Proteomic databases

PRIDEiQ5SUT0.

Expressioni

Gene expression databases

BgeeiQ5SUT0.
ExpressionAtlasiQ5SUT0. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5SUT0.
SMRiQ5SUT0. Positions 311-415.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini323 – 40987RRM (RNA recognition motif)InterPro annotationAdd
BLAST
Domaini480 – 51132RanBP2-typeInterPro annotationAdd
BLAST

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00530000063105.
HOGENOMiHOG000038010.
HOVERGENiHBG000970.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
4.10.1060.10. 1 hit.
InterProiIPR033109. EWSR1.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR001876. Znf_RanBP2.
[Graphical view]
PANTHERiPTHR23238:SF3. PTHR23238:SF3. 2 hits.
PfamiPF00076. RRM_1. 1 hit.
PF00641. zf-RanBP. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
SM00547. ZnF_RBZ. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
SSF90209. SSF90209. 1 hit.
PROSITEiPS50102. RRM. 1 hit.
PS01358. ZF_RANBP2_1. 1 hit.
PS50199. ZF_RANBP2_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SUT0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASTDYSTYS QAAAQQGYSA YTAQPTQGYA QTTQAYGQQS YGTYGQPTDV
60 70 80 90 100
SYTQAQTTAT YGQTAYATSY GQPPTGYSTP TAPQAYSQPV QGYGTGTYDS
110 120 130 140 150
TTATVTTTQA SYAAQTAYGT QPAYPTYGQQ PTATAPTRPQ DGNKPAETSQ
160 170 180 190 200
PQSSTGGYNQ PSLGYGQSNY SYPQVPGSYP MQPVTAPPSY PPTSYSSSQP
210 220 230 240 250
TSYDQSSYSQ QNTYGQPSSY GQQSSYGQQS SYGQQPPTSY PPQTGSYSQA
260 270 280 290 300
PSQYSQQSSS YGQQSSFRQD HPSSMGVYGQ ESGGFSGPGE NRSLSGPDNR
310 320 330 340 350
GRGRGGFDRG GMSRDPDEDS DNSAIYVQGL NDNVTLDDLA DFFKQCGVVK
360 370 380 390 400
MNKRTGQPMI HIYLDKETGK PKGDATVSYE DPPTAKAAVE WFDGKDFQGS
410 420 430 440 450
KLKVSLARKK PPMNSMRGGM PPREGRGMPP PLRGGPGGPG GPGGPMGRMG
460 470 480 490 500
GRGGDRGGFP PRGPRGSRGN PSGGGNVQHR AGDWQCPNPG CGNQNFAWRT
510 520 530 540 550
ECNQCKAPKP EGFLPPPFPP PGGDRGRGGP GGMRGGRGGL MDRGGPGGMF
560 570 580 590 600
RGGRGGDRGG FRGGRGMDRG GFGGGRRGGP GGPPGPLMEQ MGGRRGGRGG
610
PGKMDKGEHR QERRDRPY
Length:618
Mass (Da):64,988
Last modified:December 21, 2004 - v1
Checksum:iE90E3AEB16066CC1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645845 Genomic DNA. No translation available.
RefSeqiNP_001269991.1. NM_001283062.1.
UniGeneiMm.142822.

Genome annotation databases

EnsembliENSMUST00000073308; ENSMUSP00000073034; ENSMUSG00000009079.
GeneIDi14030.
UCSCiuc007hvy.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL645845 Genomic DNA. No translation available.
RefSeqiNP_001269991.1. NM_001283062.1.
UniGeneiMm.142822.

3D structure databases

ProteinModelPortaliQ5SUT0.
SMRiQ5SUT0. Positions 311-415.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ5SUT0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000073308; ENSMUSP00000073034; ENSMUSG00000009079.
GeneIDi14030.
UCSCiuc007hvy.2. mouse.

Organism-specific databases

CTDi2130.
MGIiMGI:99960. Ewsr1.

Phylogenomic databases

GeneTreeiENSGT00530000063105.
HOGENOMiHOG000038010.
HOVERGENiHBG000970.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiQ5SUT0.
ExpressionAtlasiQ5SUT0. baseline and differential.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
4.10.1060.10. 1 hit.
InterProiIPR033109. EWSR1.
IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR001876. Znf_RanBP2.
[Graphical view]
PANTHERiPTHR23238:SF3. PTHR23238:SF3. 2 hits.
PfamiPF00076. RRM_1. 1 hit.
PF00641. zf-RanBP. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
SM00547. ZnF_RBZ. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
SSF90209. SSF90209. 1 hit.
PROSITEiPS50102. RRM. 1 hit.
PS01358. ZF_RANBP2_1. 1 hit.
PS50199. ZF_RANBP2_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  4. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

Entry informationi

Entry nameiQ5SUT0_MOUSE
AccessioniPrimary (citable) accession number: Q5SUT0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: May 11, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.