Q5SUJ9 (Q5SUJ9_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Gamma-aminobutyric acid (GABA) B receptor, 1 EMBL CAQ06608.1

Submitted name:
Gamma-aminobutyric acid (GABA) B receptor, 1, isoform CRA_h EMBL EAX03212.1
Submitted name:
cDNA FLJ77697, highly similar to Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), transcript variant 2, mRNA EMBL BAF82880.1
Submitted name:
cDNA, FLJ92613, Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1),transcript variant 2, mRNA EMBL BAG35233.1

Gene names

Name:	GABBR1 EMBL CAQ06608.1
ORF Names:	DAMC-346D16.1-004 EMBL CAQ06608.1, hCG_22364 EMBL EAX03212.1

Organism

Homo sapiens (Human) EMBL BAG35233.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	844 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS017978
Molecular function	G-protein coupled receptor SAAS SAAS017978 Receptor Transducer
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	G-protein coupled GABA receptor activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5SUJ9 [UniParc]. Last modified May 10, 2005. Version 1. Checksum: D926376823699485	FASTA	844	95,148
	10 20 30 40 50 60 MGPGAPFARV GWPLPLLVVM AAGVAPVWAS HSPHLPRPHS RVPPHPSSER RAVYIGALFP 70 80 90 100 110 120 MSGGWPGGQA CQPAVEMALE DVNSRRDILP DYELKLIHHD SKCDPGQATK YLYELLYNDP 130 140 150 160 170 180 IKIILMPGCS SVSTLVAEAA RMWNLIVLSY GSSSPALSNR QRFPTFFRTH PSATLHNPTR 190 200 210 220 230 240 VKLFEKWGWK KIATIQQTTE VFTSTLDDLE ERVKEAGIEI TFRQSFFSDP AVPVKNLKRQ 250 260 270 280 290 300 DARIIVGLFY ETEARKVFCE VYKERLFGKK YVWFLIGWYA DNWFKIYDPS INCTVDEMTE 310 320 330 340 350 360 AVEGHITTEI VMLNPANTRS ISNMTSQEFV EKLTKRLKRH PEETGGFQEA PLAYDAIWAL 370 380 390 400 410 420 ALALNKTSGG GGRSGVRLED FNYNNQTITD QIYRAMNSSS FEGVSGHVVF DASGSRMAWT 430 440 450 460 470 480 LIEQLQGGSY KKIGYYDSTK DDLSWSKTDK WIGGSPPADQ TLVIKTFRFL SQKLFISVSV 490 500 510 520 530 540 LSSLGIVLAV VCLSFNIYNS HVRYIQNSQP NLNNLTAVGC SLALAAVFPL GLDGYHIGRN 550 560 570 580 590 600 QFPFVCQARL WLLGLGFSLG YGSMFTKIWW VHTVFTKKEE KKEWRKTLEP WKLYATVGLL 610 620 630 640 650 660 VGMDVLTLAI WQIVDPLHRT IETFAKEEPK EDIDVSILPQ LEHCSSRKMN TWLGIFYGYK 670 680 690 700 710 720 GLLLLLGIFL AYETKSVSTE KINDHRAVGM AIYNVAVLCL ITAPVTMILS SQQDAAFAFA 730 740 750 760 770 780 SLAIVFSSYI TLVVLFVPKM RRLITRGEWQ SEAQDTMKTG SSTNNNEEEK SRLLEKENRE 790 800 810 820 830 840 LEKIIAEKEE RVSELRHQLQ SRQQLRSRRH PPTPPEPSGG LPRGPPEPPD RLSCDGSRVH LLYK

References

[1]	Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M., Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J., Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S., Turner R. , Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H., Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K., Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D., Hunkapiller M.W., Myers E.W., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[2]	"NEDO human cDNA sequencing project." Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., Kisu Y., Nishikawa T. , Sugano S., Nomura N., Isogai T. Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Thalamus EMBL BAF82880.1.
[3]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Cerebellum EMBL BAG35233.1.
[4]	Gray E. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK290191 mRNA. Translation: BAF82880.1. AK312308 mRNA. Translation: BAG35233.1. CR759766 Genomic DNA. Translation: CAQ06608.1. CH471081 Genomic DNA. Translation: EAX03212.1.
IPI	IPI00218738.
RefSeq	NP_068703.1. NM_021903.2.
UniGene	Hs.167017.
3D structure databases
ProteinModelPortal	Q5SUJ9.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5SUJ9.
Proteomic databases
PRIDE	Q5SUJ9.
Protocols and materials databases
DNASU	2550.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2550.
KEGG	hsa:2550.
UCSC	uc003nmp.4. human.
Organism-specific databases
CTD	2550.
PharmGKB	PA28484.
Phylogenomic databases
HOVERGEN	HBG051688.
KO	K04615.
Gene expression databases
ArrayExpress	Q5SUJ9.
Family and domain databases
InterPro	IPR001828. ANF_lig-bd_rcpt. IPR017978. GPCR_3_C. IPR002455. GPCR_3_GABA_rcpt_B. IPR002456. GPCR_3_GABA_rcpt_B1. [Graphical view]
Pfam	PF00003. 7tm_3. 1 hit. PF01094. ANF_receptor. 1 hit. [Graphical view]
PRINTS	PR01177. GABAB1RECPTR. PR01176. GABABRECEPTR.
PROSITE	PS50259. G_PROTEIN_RECEP_F3_4. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	GABBR1. human.
GenomeRNAi	2550.
NextBio	10061.

Entry information

Entry name

Q5SUJ9_HUMAN

Accession

Primary (citable) accession number: Q5SUJ9

Entry history

Integrated into UniProtKB/TrEMBL:	May 10, 2005
Last sequence update:	May 10, 2005
Last modified:	May 1, 2013
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.