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Protein
Submitted name:

Spliceosome RNA helicase DDX39B

Gene

DDX39B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Spliceosome RNA helicase DDX39BImported
Gene namesi
Name:DDX39BImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:13917. DDX39B.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000198563.
ENSG00000215425.
ENSG00000225073.
ENSG00000225859.
ENSG00000229496.
ENSG00000230624.
ENSG00000235439.

PTM / Processingi

Proteomic databases

MaxQBiQ5STU3.
PeptideAtlasiQ5STU3.
PRIDEiQ5STU3.

Expressioni

Gene expression databases

BgeeiENSG00000198563.
ExpressionAtlasiQ5STU3. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000379475.

Structurei

3D structure databases

ProteinModelPortaliQ5STU3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini45 – 73Q_MOTIFInterPro annotationAdd BLAST29
Domaini76 – 249Helicase ATP-bindingInterPro annotationAdd BLAST174
Domaini261 – 425Helicase C-terminalInterPro annotationAdd BLAST165

Phylogenomic databases

eggNOGiKOG0329. Eukaryota.
COG0513. LUCA.
GeneTreeiENSGT00830000128348.
HOVERGENiHBG107334.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5STU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAENDVDNEL LDYEDDEVET AAGGDGAEAP AKKDVKGSYV SIHSSGFRDF
60 70 80 90 100
LLKPELLRAI VDCGFEHPSE VQHECIPQAI LGMDVLCQAK SGMGKTAVFV
110 120 130 140 150
LATLQQLEPV TGQVSVLVMC HTRELAFQIS KEYERFSKYM PNVKVAVFFG
160 170 180 190 200
GLSIKKDEEV LKKNCPHIVV GTPGRILALA RNKSLNLKHI KHFILDECDK
210 220 230 240 250
MLEQLDMRRD VQEIFRMTPH EKQVMMFSAT LSKEIRPVCR KFMQDPMEIF
260 270 280 290 300
VDDETKLTLH GLQQYYVKLK DNEKNRKLFD LLDVLEFNQV VIFVKSVQRC
310 320 330 340 350
IALAQLLVEQ NFPAIAIHRG MPQEERLSRY QQFKDFQRRI LVATNLFGRG
360 370 380 390 400
MDIERVNIAF NYDMPEDSDT YLHRCYPLSP SRWPEQAGLA PRAWLSHLCP
410 420
MRMMPRSSMM CRIALRSILV SCLMR
Length:425
Mass (Da):48,826
Last modified:February 20, 2007 - v2
Checksum:iE2E78A7794B9E959
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662801 Genomic DNA. No translation available.
AL662847 Genomic DNA. No translation available.
BX001040 Genomic DNA. No translation available.
BX248516 Genomic DNA. No translation available.
BX927320 Genomic DNA. No translation available.
CR753820 Genomic DNA. No translation available.
CR753864 Genomic DNA. No translation available.
CR753892 Genomic DNA. No translation available.
CR942185 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000376177; ENSP00000365347; ENSG00000198563.
ENST00000400293; ENSP00000383149; ENSG00000215425.
ENST00000430703; ENSP00000394329; ENSG00000229496.
ENST00000438578; ENSP00000404228; ENSG00000225073.
ENST00000446341; ENSP00000389350; ENSG00000225859.
ENST00000450987; ENSP00000407647; ENSG00000235439.
ENST00000453488; ENSP00000407427; ENSG00000230624.
UCSCiuc063nau.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662801 Genomic DNA. No translation available.
AL662847 Genomic DNA. No translation available.
BX001040 Genomic DNA. No translation available.
BX248516 Genomic DNA. No translation available.
BX927320 Genomic DNA. No translation available.
CR753820 Genomic DNA. No translation available.
CR753864 Genomic DNA. No translation available.
CR753892 Genomic DNA. No translation available.
CR942185 Genomic DNA. No translation available.

3D structure databases

ProteinModelPortaliQ5STU3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000379475.

Proteomic databases

MaxQBiQ5STU3.
PeptideAtlasiQ5STU3.
PRIDEiQ5STU3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000376177; ENSP00000365347; ENSG00000198563.
ENST00000400293; ENSP00000383149; ENSG00000215425.
ENST00000430703; ENSP00000394329; ENSG00000229496.
ENST00000438578; ENSP00000404228; ENSG00000225073.
ENST00000446341; ENSP00000389350; ENSG00000225859.
ENST00000450987; ENSP00000407647; ENSG00000235439.
ENST00000453488; ENSP00000407427; ENSG00000230624.
UCSCiuc063nau.1. human.

Organism-specific databases

HGNCiHGNC:13917. DDX39B.
OpenTargetsiENSG00000198563.
ENSG00000215425.
ENSG00000225073.
ENSG00000225859.
ENSG00000229496.
ENSG00000230624.
ENSG00000235439.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0329. Eukaryota.
COG0513. LUCA.
GeneTreeiENSGT00830000128348.
HOVERGENiHBG107334.

Miscellaneous databases

ChiTaRSiDDX39B. human.

Gene expression databases

BgeeiENSG00000198563.
ExpressionAtlasiQ5STU3. baseline and differential.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR011545. DEAD/DEAH_box_helicase_dom.
IPR014001. Helicase_ATP-bd.
IPR001650. Helicase_C.
IPR027417. P-loop_NTPase.
IPR014014. RNA_helicase_DEAD_Q_motif.
[Graphical view]
PfamiPF00270. DEAD. 1 hit.
PF00271. Helicase_C. 1 hit.
[Graphical view]
SMARTiSM00487. DEXDc. 1 hit.
SM00490. HELICc. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
PROSITEiPS51192. HELICASE_ATP_BIND_1. 1 hit.
PS51194. HELICASE_CTER. 1 hit.
PS51195. Q_MOTIF. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5STU3_HUMAN
AccessioniPrimary (citable) accession number: Q5STU3
Secondary accession number(s): Q5HYT9, Q5RJ68
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: February 20, 2007
Last modified: November 30, 2016
This is version 103 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.