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Q5STT7

- Q5STT7_MOUSE

UniProt

Q5STT7 - Q5STT7_MOUSE

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Protein
Submitted name:

Tyrosine-protein kinase ITK/TSK

Gene

Itk

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi

Functioni

GO - Biological processi

  1. interferon-gamma production Source: MGI
  2. interleukin-4 production Source: MGI
  3. intracellular signal transduction Source: InterPro
  4. NK T cell differentiation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Tyrosine-protein kinase ITK/TSKImported
Gene namesi
Name:ItkImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:96621. Itk.

Subcellular locationi

GO - Cellular componenti

  1. cell-cell junction Source: MGI
Complete GO annotation...

PTM / Processingi

Proteomic databases

PRIDEiQ5STT7.

Expressioni

Gene expression databases

ExpressionAtlasiQ5STT7. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104860.

Structurei

3D structure databases

ProteinModelPortaliQ5STT7.
SMRiQ5STT7. Positions 1-230.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation
Contains 1 SH3 domain.UniRule annotation

Keywords - Domaini

SH3 domainUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00760000119011.
HOGENOMiHOG000214181.
KOiK07363.

Family and domain databases

Gene3Di2.30.29.30. 1 hit.
InterProiIPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001452. SH3_domain.
IPR001562. Znf_Btk_motif.
[Graphical view]
PfamiPF00779. BTK. 1 hit.
PF00169. PH. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view]
PRINTSiPR00402. TECBTKDOMAIN.
SMARTiSM00107. BTK. 1 hit.
SM00233. PH. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
PS51113. ZF_BTK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5STT7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNNFILLEEQ LIKKSQQKRR TSPSNFKVRF FVLTKASLAY FEDRHGKKRT
60 70 80 90 100
LKGSIELSRI KCVEIVKSDI SIPCHYKYPF QVVHDNYLLY VFAPDCESRQ
110 120 130 140 150
RWVLTLKEET RNNNSLVSKY HPNFWMDGRW RCCSQLEKPA VGCAPYDPSK
160 170 180 190 200
NASKKPLPPT PEDNRRSFQE PEETLVIALY DYQTNDPQEL ALRCDEEYYL
210 220 230 240 250
LDSSEIHWWR VQDKNGHEGY APSSYLVEKS PNNLETYEWY NKSISRDKAE
260
KLLLDTVKKW TRIL
Length:264
Mass (Da):31,287
Last modified:December 21, 2004 - v1
Checksum:iA8C30A72892DC755
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL662806 Genomic DNA. No translation available.
RefSeqiNP_001268896.1. NM_001281967.1.
UniGeneiMm.339927.

Genome annotation databases

EnsembliENSMUST00000101306; ENSMUSP00000098864; ENSMUSG00000020395.
GeneIDi16428.
KEGGimmu:16428.
UCSCiuc007ioh.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL662806 Genomic DNA. No translation available.
RefSeqi NP_001268896.1. NM_001281967.1.
UniGenei Mm.339927.

3D structure databases

ProteinModelPortali Q5STT7.
SMRi Q5STT7. Positions 1-230.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000104860.

Proteomic databases

PRIDEi Q5STT7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000101306 ; ENSMUSP00000098864 ; ENSMUSG00000020395 .
GeneIDi 16428.
KEGGi mmu:16428.
UCSCi uc007ioh.1. mouse.

Organism-specific databases

CTDi 3702.
MGIi MGI:96621. Itk.

Phylogenomic databases

GeneTreei ENSGT00760000119011.
HOGENOMi HOG000214181.
KOi K07363.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

ExpressionAtlasi Q5STT7. baseline and differential.

Family and domain databases

Gene3Di 2.30.29.30. 1 hit.
InterProi IPR001849. PH_domain.
IPR011993. PH_like_dom.
IPR001452. SH3_domain.
IPR001562. Znf_Btk_motif.
[Graphical view ]
Pfami PF00779. BTK. 1 hit.
PF00169. PH. 1 hit.
PF00018. SH3_1. 1 hit.
[Graphical view ]
PRINTSi PR00402. TECBTKDOMAIN.
SMARTi SM00107. BTK. 1 hit.
SM00233. PH. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view ]
SUPFAMi SSF50044. SSF50044. 1 hit.
PROSITEi PS50003. PH_DOMAIN. 1 hit.
PS50002. SH3. 1 hit.
PS51113. ZF_BTK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  2. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ5STT7_MOUSE
AccessioniPrimary (citable) accession number: Q5STT7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: October 29, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3