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Q5STT7

- Q5STT7_MOUSE

UniProt

Q5STT7 - Q5STT7_MOUSE

Protein
Submitted name:

Tyrosine-protein kinase ITK/TSK

Gene

Itk

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Protein predictedi
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    • History
      Entry version 75 (01 Oct 2014)
      Sequence version 1 (21 Dec 2004)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. interferon-gamma production Source: MGI
    2. interleukin-4 production Source: MGI
    3. intracellular signal transduction Source: InterPro
    4. NK T cell differentiation Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Tyrosine-protein kinase ITK/TSKImported
    Gene namesi
    Name:ItkImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 11

    Organism-specific databases

    MGIiMGI:96621. Itk.

    Subcellular locationi

    GO - Cellular componenti

    1. cell-cell junction Source: MGI

    PTM / Processingi

    Proteomic databases

    PRIDEiQ5STT7.

    Expressioni

    Gene expression databases

    ArrayExpressiQ5STT7.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000104860.

    Structurei

    3D structure databases

    ProteinModelPortaliQ5STT7.
    SMRiQ5STT7. Positions 1-230.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 PH domain.UniRule annotation
    Contains 1 SH3 domain.UniRule annotation

    Keywords - Domaini

    SH3 domainUniRule annotation

    Phylogenomic databases

    GeneTreeiENSGT00640000091251.
    HOGENOMiHOG000214181.
    KOiK07363.

    Family and domain databases

    Gene3Di2.30.29.30. 1 hit.
    InterProiIPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR001452. SH3_domain.
    IPR001562. Znf_Btk_motif.
    [Graphical view]
    PfamiPF00779. BTK. 1 hit.
    PF00169. PH. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view]
    PRINTSiPR00402. TECBTKDOMAIN.
    SMARTiSM00107. BTK. 1 hit.
    SM00233. PH. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view]
    SUPFAMiSSF50044. SSF50044. 1 hit.
    PROSITEiPS50003. PH_DOMAIN. 1 hit.
    PS50002. SH3. 1 hit.
    PS51113. ZF_BTK. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5STT7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNNFILLEEQ LIKKSQQKRR TSPSNFKVRF FVLTKASLAY FEDRHGKKRT    50
    LKGSIELSRI KCVEIVKSDI SIPCHYKYPF QVVHDNYLLY VFAPDCESRQ 100
    RWVLTLKEET RNNNSLVSKY HPNFWMDGRW RCCSQLEKPA VGCAPYDPSK 150
    NASKKPLPPT PEDNRRSFQE PEETLVIALY DYQTNDPQEL ALRCDEEYYL 200
    LDSSEIHWWR VQDKNGHEGY APSSYLVEKS PNNLETYEWY NKSISRDKAE 250
    KLLLDTVKKW TRIL 264
    Length:264
    Mass (Da):31,287
    Last modified:December 21, 2004 - v1
    Checksum:iA8C30A72892DC755
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL662806 Genomic DNA. No translation available.
    RefSeqiNP_001268896.1. NM_001281967.1.
    UniGeneiMm.339927.

    Genome annotation databases

    EnsembliENSMUST00000101306; ENSMUSP00000098864; ENSMUSG00000020395.
    GeneIDi16428.
    KEGGimmu:16428.
    UCSCiuc007ioh.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL662806 Genomic DNA. No translation available.
    RefSeqi NP_001268896.1. NM_001281967.1.
    UniGenei Mm.339927.

    3D structure databases

    ProteinModelPortali Q5STT7.
    SMRi Q5STT7. Positions 1-230.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000104860.

    Proteomic databases

    PRIDEi Q5STT7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000101306 ; ENSMUSP00000098864 ; ENSMUSG00000020395 .
    GeneIDi 16428.
    KEGGi mmu:16428.
    UCSCi uc007ioh.1. mouse.

    Organism-specific databases

    CTDi 3702.
    MGIi MGI:96621. Itk.

    Phylogenomic databases

    GeneTreei ENSGT00640000091251.
    HOGENOMi HOG000214181.
    KOi K07363.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q5STT7.

    Family and domain databases

    Gene3Di 2.30.29.30. 1 hit.
    InterProi IPR001849. PH_domain.
    IPR011993. PH_like_dom.
    IPR001452. SH3_domain.
    IPR001562. Znf_Btk_motif.
    [Graphical view ]
    Pfami PF00779. BTK. 1 hit.
    PF00169. PH. 1 hit.
    PF00018. SH3_1. 1 hit.
    [Graphical view ]
    PRINTSi PR00402. TECBTKDOMAIN.
    SMARTi SM00107. BTK. 1 hit.
    SM00233. PH. 1 hit.
    SM00326. SH3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50044. SSF50044. 1 hit.
    PROSITEi PS50003. PH_DOMAIN. 1 hit.
    PS50002. SH3. 1 hit.
    PS51113. ZF_BTK. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    2. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ5STT7_MOUSE
    AccessioniPrimary (citable) accession number: Q5STT7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 21, 2004
    Last sequence update: December 21, 2004
    Last modified: October 1, 2014
    This is version 75 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Caution

    The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3