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Protein
Submitted name:

FLOT1

Gene

FLOT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
FLOT1Imported
Submitted name:
FLOT1 proteinImported
Submitted name:
Flotillin 1Imported
Submitted name:
Flotillin 1, isoform CRA_bImported
Gene namesi
Name:FLOT1Imported
ORF Names:hCG_2006678Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000137312.14

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28175

PTM / Processingi

Proteomic databases

MaxQBiQ5ST80
PRIDEiQ5ST80

Expressioni

Gene expression databases

BgeeiENSG00000137312
ExpressionAtlasiQ5ST80 baseline and differential

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini84 – 266PHBInterPro annotationAdd BLAST183

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili242 – 262Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2668 Eukaryota
COG2268 LUCA
HOVERGENiHBG051628
KOiK07192
OMAiQYDSEVK
OrthoDBiEOG091G0D3R

Family and domain databases

InterProiView protein in InterPro
IPR001107 Band_7
IPR036013 Band_7/SPFH_dom_sf
IPR031905 Flotillin_C
IPR027705 Flotillin_fam
PANTHERiPTHR13806 PTHR13806, 1 hit
PfamiView protein in Pfam
PF01145 Band_7, 1 hit
PF15975 Flot, 1 hit
SMARTiView protein in SMART
SM00244 PHB, 1 hit
SUPFAMiSSF117892 SSF117892, 1 hit

Sequencei

Sequence statusi: Complete.

Q5ST80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFTCGPNEA MVVSGFCRSP PVMVAGGRVF VLPCIQQIQR ISLNTLTLNV
60 70 80 90 100
KSEKVYTRHG VPISVTGIAQ VKIQGQNKEM LAAACQMFLG KTEAEIAHIA
110 120 130 140 150
LETLEGHQRA IMAHMTVEEI YKDRQKFSEQ VFKVASSDLV NMGISVVSYT
160 170 180 190 200
LKDIHDDQDY LHSLGKARTA QVQKDARIGE AEAKRDAGIR EAKAKQEKVS
210 220 230 240 250
AQYLSEIEMA KAQRDYELKK AAYDIEVNTR RAQADLAYQL QVAKTKQQIE
260 270 280 290 300
EQRVQVQVVE RAQQVAVQEQ EIARREKELE ARVRKPAEAE RYKLERLAEA
310 320 330 340 350
EKSQLIMQAE AEAASVRMRG EAEAFAIGAR ARAEAEQMAK KAEAFQLYQE
360 370 380 390 400
AAQLDMLLEK LPQVAEEISG PLTSANKITL VSSGSGTMGA AKVTGEVLDI
410 420
LTRLPESVER LTGVSISQVN HKPLRTA
Length:427
Mass (Da):47,355
Last modified:May 10, 2005 - v1
Checksum:iC69E5421E565F53A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007077 mRNA Translation: AAP35740.1
KY500328 Genomic DNA Translation: AQY76816.1
KY500329 Genomic DNA Translation: AQY76817.1
KY500330 Genomic DNA Translation: AQY76818.1
AB088101 Genomic DNA Translation: BAC54934.1
AB202099 Genomic DNA Translation: BAE78620.1
AB103607 Genomic DNA Translation: BAF31269.1
CH471081 Genomic DNA Translation: EAX03326.1
CH471081 Genomic DNA Translation: EAX03327.1
RefSeqiNP_005794.1, NM_005803.3
XP_005248837.1, XM_005248780.3
UniGeneiHs.179986

Genome annotation databases

GeneIDi10211
KEGGihsa:10211
UCSCiuc003nrm.4 human

Similar proteinsi

Entry informationi

Entry nameiQ5ST80_HUMAN
AccessioniPrimary (citable) accession number: Q5ST80
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 129 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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