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Protein
Submitted name:

FLOT1

Gene

FLOT1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
FLOT1Imported
Submitted name:
FLOT1 proteinImported
Submitted name:
Flotillin 1Imported
Submitted name:
Flotillin 1, isoform CRA_bImported
Gene namesi
Name:FLOT1Imported
ORF Names:hCG_2006678Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000137312.14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28175.

PTM / Processingi

Proteomic databases

MaxQBiQ5ST80.

Expressioni

Gene expression databases

BgeeiENSG00000137312.
ExpressionAtlasiQ5ST80. baseline and differential.

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini84 – 266PHBInterPro annotationAdd BLAST183

Phylogenomic databases

eggNOGiKOG2668. Eukaryota.
COG2268. LUCA.
HOVERGENiHBG051628.
KOiK07192.
OMAiQYDSEVK.
OrthoDBiEOG091G0D3R.

Family and domain databases

InterProiView protein in InterPro
IPR001107. Band_7.
IPR031905. Flotillin_C.
IPR027705. Flotillin_fam.
PANTHERiPTHR13806. PTHR13806. 1 hit.
PfamiView protein in Pfam
PF01145. Band_7. 1 hit.
PF15975. Flot. 1 hit.
SMARTiView protein in SMART
SM00244. PHB. 1 hit.
SUPFAMiSSF117892. SSF117892. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5ST80-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFFTCGPNEA MVVSGFCRSP PVMVAGGRVF VLPCIQQIQR ISLNTLTLNV
60 70 80 90 100
KSEKVYTRHG VPISVTGIAQ VKIQGQNKEM LAAACQMFLG KTEAEIAHIA
110 120 130 140 150
LETLEGHQRA IMAHMTVEEI YKDRQKFSEQ VFKVASSDLV NMGISVVSYT
160 170 180 190 200
LKDIHDDQDY LHSLGKARTA QVQKDARIGE AEAKRDAGIR EAKAKQEKVS
210 220 230 240 250
AQYLSEIEMA KAQRDYELKK AAYDIEVNTR RAQADLAYQL QVAKTKQQIE
260 270 280 290 300
EQRVQVQVVE RAQQVAVQEQ EIARREKELE ARVRKPAEAE RYKLERLAEA
310 320 330 340 350
EKSQLIMQAE AEAASVRMRG EAEAFAIGAR ARAEAEQMAK KAEAFQLYQE
360 370 380 390 400
AAQLDMLLEK LPQVAEEISG PLTSANKITL VSSGSGTMGA AKVTGEVLDI
410 420
LTRLPESVER LTGVSISQVN HKPLRTA
Length:427
Mass (Da):47,355
Last modified:May 10, 2005 - v1
Checksum:iC69E5421E565F53A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT007077 mRNA. Translation: AAP35740.1.
KY500328 Genomic DNA. Translation: AQY76816.1.
KY500329 Genomic DNA. Translation: AQY76817.1.
KY500330 Genomic DNA. Translation: AQY76818.1.
AB088101 Genomic DNA. Translation: BAC54934.1.
AB202099 Genomic DNA. Translation: BAE78620.1.
AB103607 Genomic DNA. Translation: BAF31269.1.
CH471081 Genomic DNA. Translation: EAX03326.1.
CH471081 Genomic DNA. Translation: EAX03327.1.
RefSeqiNP_005794.1. NM_005803.3.
XP_005248837.1. XM_005248780.3.
UniGeneiHs.179986.

Genome annotation databases

GeneIDi10211.
KEGGihsa:10211.
UCSCiuc003nrm.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ5ST80_HUMAN
AccessioniPrimary (citable) accession number: Q5ST80
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.