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Q5SS91

- SUN3_MOUSE

UniProt

Q5SS91 - SUN3_MOUSE

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Protein

SUN domain-containing protein 3

Gene

Sun3

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
SUN domain-containing protein 3
Alternative name(s):
Sad1/unc-84 domain-containing protein 1
Gene namesi
Name:Sun3
Synonyms:Sunc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:3041199. Sun3.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. SUN-KASH complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 320320SUN domain-containing protein 3PRO_0000312222Add
BLAST

Proteomic databases

PaxDbiQ5SS91.
PRIDEiQ5SS91.

PTM databases

PhosphoSiteiQ5SS91.

Expressioni

Gene expression databases

BgeeiQ5SS91.
CleanExiMM_SUNC1.
ExpressionAtlasiQ5SS91. baseline.
GenevestigatoriQ5SS91.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045199.

Structurei

3D structure databases

ProteinModelPortaliQ5SS91.
SMRiQ5SS91. Positions 124-317.
ModBaseiSearch...
MobiDBiSearch...

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei7 – 2923HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini156 – 317162SUNPROSITE-ProRule annotationAdd
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili63 – 10240Sequence AnalysisAdd
BLAST

Sequence similaritiesi

Contains 1 SUN domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG285464.
GeneTreeiENSGT00390000011587.
HOGENOMiHOG000007503.
HOVERGENiHBG108520.
InParanoidiQ5SS91.
OMAiRVHGTPG.
OrthoDBiEOG7J446H.
PhylomeDBiQ5SS91.
TreeFamiTF323915.

Family and domain databases

InterProiIPR012919. Sad1_UNC_C.
[Graphical view]
PfamiPF07738. Sad1_UNC. 1 hit.
[Graphical view]
PROSITEiPS51469. SUN. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q5SS91-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MLTRSWKIIL STVFISTFLL VGLLNHQWLK ETEFPQKPRQ LYTVIAEYGS
60 70 80 90 100
RLYNYQARLR MPKEQQELLK KESQTLENNF REILFLIEQI DVLKALLKDM
110 120 130 140 150
KDGVHNHSLP VHRDAVQDQA TTDVLDEEMS NLVHYVLKKF RGDQIQLADY
160 170 180 190 200
ALKSAGASVI EAGTSESYKN NKAKLYWHGI GFLNYEMPPD MILQPDVHPG
210 220 230 240 250
KCWAFPGSQG HILIKLARKI IPTAVTMEHI SEKVSPSGNI SSAPKEFSVY
260 270 280 290 300
GVMKKCEGEE IFLGQFIYNK MEATIQTFEL QNEASESLLC VKLQILSNWG
310 320
HPKYTCLYRF RVHGIPSDYT
Length:320
Mass (Da):36,758
Last modified:December 21, 2004 - v1
Checksum:i8DEC1E6B0D0BC1FB
GO
Isoform 2 (identifier: Q5SS91-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-60: Missing.

Show »
Length:260
Mass (Da):29,544
Checksum:iABF66504F0D13B7F
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 6060Missing in isoform 2. 2 PublicationsVSP_029750Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK052771 mRNA. Translation: BAC35140.1.
AK132922 mRNA. Translation: BAE21423.1.
AL669837 Genomic DNA. Translation: CAI24620.1.
AL669837 Genomic DNA. Translation: CAI24621.1.
BC109334 mRNA. Translation: AAI09335.1.
CCDSiCCDS24430.1. [Q5SS91-2]
CCDS70140.1. [Q5SS91-1]
RefSeqiNP_001277448.1. NM_001290519.1. [Q5SS91-1]
NP_001277449.1. NM_001290520.1. [Q5SS91-2]
NP_808244.1. NM_177576.3. [Q5SS91-2]
UniGeneiMm.79210.

Genome annotation databases

EnsembliENSMUST00000043377; ENSMUSP00000045199; ENSMUSG00000040985. [Q5SS91-1]
ENSMUST00000102909; ENSMUSP00000099973; ENSMUSG00000040985. [Q5SS91-2]
GeneIDi194974.
KEGGimmu:194974.
UCSCiuc007hzt.1. mouse. [Q5SS91-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK052771 mRNA. Translation: BAC35140.1 .
AK132922 mRNA. Translation: BAE21423.1 .
AL669837 Genomic DNA. Translation: CAI24620.1 .
AL669837 Genomic DNA. Translation: CAI24621.1 .
BC109334 mRNA. Translation: AAI09335.1 .
CCDSi CCDS24430.1. [Q5SS91-2 ]
CCDS70140.1. [Q5SS91-1 ]
RefSeqi NP_001277448.1. NM_001290519.1. [Q5SS91-1 ]
NP_001277449.1. NM_001290520.1. [Q5SS91-2 ]
NP_808244.1. NM_177576.3. [Q5SS91-2 ]
UniGenei Mm.79210.

3D structure databases

ProteinModelPortali Q5SS91.
SMRi Q5SS91. Positions 124-317.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000045199.

PTM databases

PhosphoSitei Q5SS91.

Proteomic databases

PaxDbi Q5SS91.
PRIDEi Q5SS91.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000043377 ; ENSMUSP00000045199 ; ENSMUSG00000040985 . [Q5SS91-1 ]
ENSMUST00000102909 ; ENSMUSP00000099973 ; ENSMUSG00000040985 . [Q5SS91-2 ]
GeneIDi 194974.
KEGGi mmu:194974.
UCSCi uc007hzt.1. mouse. [Q5SS91-1 ]

Organism-specific databases

CTDi 256979.
MGIi MGI:3041199. Sun3.

Phylogenomic databases

eggNOGi NOG285464.
GeneTreei ENSGT00390000011587.
HOGENOMi HOG000007503.
HOVERGENi HBG108520.
InParanoidi Q5SS91.
OMAi RVHGTPG.
OrthoDBi EOG7J446H.
PhylomeDBi Q5SS91.
TreeFami TF323915.

Miscellaneous databases

NextBioi 371685.
PROi Q5SS91.
SOURCEi Search...

Gene expression databases

Bgeei Q5SS91.
CleanExi MM_SUNC1.
ExpressionAtlasi Q5SS91. baseline.
Genevestigatori Q5SS91.

Family and domain databases

InterProi IPR012919. Sad1_UNC_C.
[Graphical view ]
Pfami PF07738. Sad1_UNC. 1 hit.
[Graphical view ]
PROSITEi PS51469. SUN. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Strain: C57BL/6J.
    Tissue: Kidney and Testis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).

Entry informationi

Entry nameiSUN3_MOUSE
AccessioniPrimary (citable) accession number: Q5SS91
Secondary accession number(s): Q8BHY0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 4, 2007
Last sequence update: December 21, 2004
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3