Q5SRT3 (Q5SRT3_HUMAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Chloride intracellular channel 1 EMBL CAM45776.1

Submitted name:
cDNA, FLJ94671, Homo sapiens chloride intracellular channel 1 (CLIC1), mRNA EMBL BAG36725.1

Gene names

Name:	CLIC1 EMBL CAM45776.1
ORF Names:	DADB-110M10.1-001 EMBL CAQ08899.1, DAMA-236L13.3-001 EMBL CAQ07026.1, DAMC-117B11.2-001 EMBL CAQ10114.1, DAQB-350E15.4-001 EMBL CAM45776.1, DASS-312M4.8-001 EMBL CAM26101.1

Organism

Homo sapiens (Human) EMBL CAM45776.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	241 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 GST C-terminal domain. SAAS SAAS017933

Ontologies

Gene Ontology (GO)
Cellular component	membrane Inferred from electronic annotation. Source: InterPro
Molecular function	voltage-gated chloride channel activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5SRT3 [UniParc]. Last modified February 20, 2007. Version 2. Checksum: 163EEB7481826A0A	FASTA	241	26,923
	10 20 30 40 50 60 MAEEQPQVEL FVKAGSDGAK IGNCPFSQRL FMVLWLKGVT FNVTTVDTKR RTETVQKLCP 70 80 90 100 110 120 GGQLPFLLYG TEVHTDTNKI EEFLEAVLCP PRYPKLAALN PESNTAGLDI FAKFSAYIKN 130 140 150 160 170 180 SNPALNDNLE KGLLKALKVL DNYLTSPLPE EVDETSAEDE GVSQRKFLDG NELTLADCNL 190 200 210 220 230 240 LPKLHIVQVV CKKYRGFTIP EAFRGVHRYL SNAYAREEFA STCPDDEEIE LAYEQVAKAL K

References

[1]	"NEDO functional analysis of protein and research application project." Wakamatsu A., Yamamoto J., Kimura K., Kaida T., Tsuchiya K., Iida Y., Takayama Y., Murakawa K., Kanehori K., Andoh T., Kagawa N., Sato R., Kawamura Y., Tanaka S., Kisu Y., Sugano S., Goshima N., Nomura N., Isogai T. Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Tissue: Trachea EMBL BAG36725.1.
[2]	Wood J. Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[3]	Griffiths C. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[4]	Tracey A. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
[5]	Gray E. Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK314014 mRNA. Translation: BAG36725.1. BX248244 Genomic DNA. Translation: CAM26101.1. AL844216 Genomic DNA. Translation: CAM45776.1. CR354443 Genomic DNA. Translation: CAQ07026.1. CR936239 Genomic DNA. Translation: CAQ08899.1. CR759787 Genomic DNA. Translation: CAQ10114.1.
IPI	IPI00010896.
RefSeq	NP_001279.2. NM_001288.4.
UniGene	Hs.414565.
3D structure databases
ProteinModelPortal	Q5SRT3.
SMR	Q5SRT3. Positions 22-234.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5SRT3.
Proteomic databases
PRIDE	Q5SRT3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1192.
KEGG	hsa:1192.
Organism-specific databases
CTD	1192.
Phylogenomic databases
GeneTree	ENSGT00550000074477.
HOVERGEN	HBG050994.
OMA	REEFSST.
PhylomeDB	Q5SRT3.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR002946. Int_Cl_channel. IPR012336. Thioredoxin-like_fold. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit.
KO	K05021.
PRINTS	PR01263. INTCLCHANNEL.
SUPFAM	SSF47616. GST_C_like. 1 hit. SSF52833. Thiordxn-like_fd. 1 hit.
TIGRFAMs	TIGR00862. O-ClC. 1 hit.
PROSITE	PS50405. GST_CTER. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	4928.

Entry information

Entry name

Q5SRT3_HUMAN

Accession

Primary (citable) accession number: Q5SRT3

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	February 20, 2007
Last modified:	November 16, 2011
This is version 65 of the entry and version 2 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.