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Protein

Casein kinase II subunit beta

Gene

CSNK2B

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Plays a complex role in regulating the basal catalytic activity of the alpha subunit.UniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
Casein kinase II subunit betaUniRule annotation
Short name:
CK II betaUniRule annotation
Gene namesi
Name:CSNK2BImported
ORF Names:hCG_43725Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 6

Organism-specific databases

HGNCiHGNC:2460. CSNK2B.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204435.
ENSG00000206406.
ENSG00000224398.
ENSG00000224774.
ENSG00000228875.
ENSG00000230700.
ENSG00000232960.

PTM / Processingi

Proteomic databases

EPDiQ5SRQ6.
MaxQBiQ5SRQ6.
PRIDEiQ5SRQ6.

Expressioni

Gene expression databases

BgeeiENSG00000204435.
ExpressionAtlasiQ5SRQ6. baseline and differential.

Interactioni

Subunit structurei

Tetramer of two alpha and two beta subunits.UniRule annotation

Protein-protein interaction databases

IntActiQ5SRQ6. 4 interactors.
STRINGi9606.ENSP00000365025.

Structurei

3D structure databases

ProteinModelPortaliQ5SRQ6.
SMRiQ5SRQ6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the casein kinase 2 subunit beta family.UniRule annotation

Phylogenomic databases

eggNOGiKOG3092. Eukaryota.
COG5041. LUCA.
GeneTreeiENSGT00390000003781.
HOGENOMiHOG000039270.
OMAiPRVNCSG.
OrthoDBiEOG091G0L2H.
PhylomeDBiQ5SRQ6.

Family and domain databases

Gene3Di1.10.1820.10. 1 hit.
2.20.25.20. 1 hit.
InterProiIPR016149. Casein_kin_II_reg-sub_a-hlx.
IPR016150. Casein_kin_II_reg-sub_b-sht.
IPR000704. Casein_kinase_II_reg-sub.
[Graphical view]
PANTHERiPTHR11740. PTHR11740. 1 hit.
PfamiPF01214. CK_II_beta. 1 hit.
[Graphical view]
PRINTSiPR00472. CASNKINASEII.
SMARTiSM01085. CK_II_beta. 1 hit.
[Graphical view]
SUPFAMiSSF57798. SSF57798. 1 hit.
PROSITEiPS01101. CK2_BETA. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SRQ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKCKGTSRM AGTTSADVKM SSSEEVSWIS WFCGLRGNEF FCEVDEDYIQ
60 70 80 90 100
DKFNLTGLNE QVPHYRQALD MILDLEPDEE LEDNPNQSDL IEQAAEMLYG
110 120 130 140 150
LIHARYILTN RGIAQMLEKY QQGDFGYCPR VYCENQPMLP IGLSDIPGEA
160 170 180 190 200
MVKLYCPKCM DVYTPKSSRH HHTDGAYFGT GFPHMLFMVH PEYRPKRPAN
210 220 230
QFVPRLYGFK IHPMAYQLQL QAASNFKSPV KTIR
Length:234
Mass (Da):26,926
Last modified:February 20, 2007 - v2
Checksum:i89A9DA60278593D9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662899 Genomic DNA. No translation available.
AL670886 Genomic DNA. No translation available.
AL805934 Genomic DNA. No translation available.
BX511262 Genomic DNA. No translation available.
CR354443 Genomic DNA. No translation available.
CR753842 Genomic DNA. No translation available.
CR759761 Genomic DNA. No translation available.
CH471081 Genomic DNA. Translation: EAX03475.1.
UniGeneiHs.73527.

Genome annotation databases

EnsembliENST00000375885; ENSP00000365046; ENSG00000204435.
ENST00000400116; ENSP00000382984; ENSG00000206406.
ENST00000422261; ENSP00000413092; ENSG00000224398.
ENST00000424502; ENSP00000396772; ENSG00000230700.
ENST00000428483; ENSP00000395546; ENSG00000232960.
ENST00000432290; ENSP00000415615; ENSG00000224774.
ENST00000439572; ENSP00000410942; ENSG00000228875.
UCSCiuc063nej.1. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL662899 Genomic DNA. No translation available.
AL670886 Genomic DNA. No translation available.
AL805934 Genomic DNA. No translation available.
BX511262 Genomic DNA. No translation available.
CR354443 Genomic DNA. No translation available.
CR753842 Genomic DNA. No translation available.
CR759761 Genomic DNA. No translation available.
CH471081 Genomic DNA. Translation: EAX03475.1.
UniGeneiHs.73527.

3D structure databases

ProteinModelPortaliQ5SRQ6.
SMRiQ5SRQ6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5SRQ6. 4 interactors.
STRINGi9606.ENSP00000365025.

Proteomic databases

EPDiQ5SRQ6.
MaxQBiQ5SRQ6.
PRIDEiQ5SRQ6.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000375885; ENSP00000365046; ENSG00000204435.
ENST00000400116; ENSP00000382984; ENSG00000206406.
ENST00000422261; ENSP00000413092; ENSG00000224398.
ENST00000424502; ENSP00000396772; ENSG00000230700.
ENST00000428483; ENSP00000395546; ENSG00000232960.
ENST00000432290; ENSP00000415615; ENSG00000224774.
ENST00000439572; ENSP00000410942; ENSG00000228875.
UCSCiuc063nej.1. human.

Organism-specific databases

HGNCiHGNC:2460. CSNK2B.
OpenTargetsiENSG00000204435.
ENSG00000206406.
ENSG00000224398.
ENSG00000224774.
ENSG00000228875.
ENSG00000230700.
ENSG00000232960.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG3092. Eukaryota.
COG5041. LUCA.
GeneTreeiENSGT00390000003781.
HOGENOMiHOG000039270.
OMAiPRVNCSG.
OrthoDBiEOG091G0L2H.
PhylomeDBiQ5SRQ6.

Gene expression databases

BgeeiENSG00000204435.
ExpressionAtlasiQ5SRQ6. baseline and differential.

Family and domain databases

Gene3Di1.10.1820.10. 1 hit.
2.20.25.20. 1 hit.
InterProiIPR016149. Casein_kin_II_reg-sub_a-hlx.
IPR016150. Casein_kin_II_reg-sub_b-sht.
IPR000704. Casein_kinase_II_reg-sub.
[Graphical view]
PANTHERiPTHR11740. PTHR11740. 1 hit.
PfamiPF01214. CK_II_beta. 1 hit.
[Graphical view]
PRINTSiPR00472. CASNKINASEII.
SMARTiSM01085. CK_II_beta. 1 hit.
[Graphical view]
SUPFAMiSSF57798. SSF57798. 1 hit.
PROSITEiPS01101. CK2_BETA. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SRQ6_HUMAN
AccessioniPrimary (citable) accession number: Q5SRQ6
Secondary accession number(s): Q5SQ53
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: February 20, 2007
Last modified: November 30, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.