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Protein
Submitted name:

TRIM15

Gene

TRIM15

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
TRIM15Imported
Submitted name:
Tripartite motif-containing 15Imported
Submitted name:
cDNA FLJ75016, highly similar to Homo sapiens tripartite motif-containing 15 (TRIM15), transcript variant 1, mRNAImported
Gene namesi
Name:TRIM15Imported
ORF Names:hCG_23773Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000204610.12

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA38114

PTM / Processingi

Proteomic databases

PRIDEiQ5SRL0

Expressioni

Gene expression databases

BgeeiENSG00000204610
ExpressionAtlasiQ5SRL0 baseline and differential

Structurei

3D structure databases

SMRiQ5SRL0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini16 – 61RING-typeInterPro annotationAdd BLAST46
Domaini78 – 119B box-typeInterPro annotationAdd BLAST42
Domaini276 – 465B30.2/SPRYInterPro annotationAdd BLAST190

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili127 – 147Sequence analysisAdd BLAST21
Coiled coili159 – 186Sequence analysisAdd BLAST28
Coiled coili206 – 226Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG2177 Eukaryota
ENOG4111G04 LUCA
HOVERGENiHBG001357
KOiK12005
OMAiQQCWAST
OrthoDBiEOG091G05W2

Family and domain databases

CDDicd00021 BBOX, 1 hit
Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR001870 B30.2/SPRY
IPR003879 Butyrophylin_SPRY
IPR013320 ConA-like_dom_sf
IPR006574 PRY
IPR003877 SPRY_dom
IPR000315 Znf_B-box
IPR018957 Znf_C3HC4_RING-type
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PfamiView protein in Pfam
PF13765 PRY, 1 hit
PF00622 SPRY, 1 hit
PF00643 zf-B_box, 1 hit
PF00097 zf-C3HC4, 1 hit
PRINTSiPR01407 BUTYPHLNCDUF
SMARTiView protein in SMART
SM00336 BBOX, 1 hit
SM00589 PRY, 1 hit
SM00184 RING, 1 hit
SM00449 SPRY, 1 hit
SUPFAMiSSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS50188 B302_SPRY, 1 hit
PS50119 ZF_BBOX, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5SRL0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPATPSLKVV HELPACTLCA GPLEDAVTIP CGHTFCRLCL PALSQMGAQS
60 70 80 90 100
SGKILLCPLC QEEEQAETPM APVPLGPLGE TYCEEHGEKI YFFCENDAEF
110 120 130 140 150
LCVFCREGPT HQAHTVGFLD EAIQPYRDRL RSRLEALSTE RDEIEDVKCQ
160 170 180 190 200
EDQKLQVLLT QIESKKHQVE TAFERLQQEL EQQRCLLLAR LRELEQQIWK
210 220 230 240 250
ERDEYITKVS EEVTRLGAQV KELEEKCQQP ASELLQDVRV NQSRCEMKTF
260 270 280 290 300
VSPEAISPDL VKKIRDFHRK ILTLPEMMRM FSENLAHHLE IDSGVITLDP
310 320 330 340 350
QTASRSLVLS EDRKSVRYTR QKKSLPDSPL RFDGLPAVLG FPGFSSGRHR
360 370 380 390 400
WQVDLQLGDG GGCTVGVAGE GVRRKGEMGL SAEDGVWAVI ISHQQCWAST
410 420 430 440 450
SPGTDLPLSE IPRGVRVALD YEAGQVTLHN AQTQEPIFTF TASFSGKVFP
460
FFAVWKKGSC LTLKG
Length:465
Mass (Da):52,113
Last modified:May 10, 2005 - v1
Checksum:i303B8BF8623CB00A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
KY500683 Genomic DNA Translation: AQY77155.1
KY500685 Genomic DNA Translation: AQY77157.1
KY500687 Genomic DNA Translation: AQY77159.1
AB202085 Genomic DNA Translation: BAE78606.1
AK291853 mRNA Translation: BAF84542.1
CH471081 Genomic DNA Translation: EAX03271.1
RefSeqiNP_150232.2, NM_033229.2
UniGeneiHs.591789
Hs.606488

Genome annotation databases

GeneIDi89870
KEGGihsa:89870

Similar proteinsi

Entry informationi

Entry nameiQ5SRL0_HUMAN
AccessioniPrimary (citable) accession number: Q5SRL0
Secondary accession number(s): A6NEF7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 146 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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