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Unreviewed, UniProtKB/TrEMBL Q5SR50 (Q5SR50_HUMAN)

Last modified January 19, 2010. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    Phosphoinositide-3-kinase, catalytic, delta polypeptide EMBL CAI15702.1
Gene names
Name: PIK3CD EMBL CAI15702.1
ORF Names: RP11-558F24.3-003 EMBL CAI15702.1
OrganismHomo sapiens (Human) EMBL CAI15702.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length1068 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Sequence similarities

Contains 1 PI3K/PI4K domain.

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Sequences

Sequence LengthMass (Da)Tools
Q5SR50-1 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: D1A2D448773E0BFE

FASTA1,068122,005
        10         20         30         40         50         60 
MPPGVDCPME FWTKEENQSV VVDFLLPTGV YLNFPVSRNA NLSTIKQLLW HRAQYEPLFH 

        70         80         90        100        110        120 
MLSGPEAYVF TCINQTAEQQ ELEDEQRRLC DVQPFLPVLR LVAREGDRVK KLINSQISLL 

       130        140        150        160        170        180 
IGKGLHEFDS LCDPEVNDFR AKMCQFCEEA AARRQQLGWE AWLQYSFPLQ LEPSAQTWGP 

       190        200        210        220        230        240 
GTLRLPNRAL LVNVKFEGSE ESFTFQVSTK DVPLALMACA LRKKATVFRQ PLVEQPEDYT 

       250        260        270        280        290        300 
LQVNGRHEYL YGSYPLCQFQ VQKPRAKPPP IPAKKPSSVS LWSLEQPFRI ELIQGSKVNA 

       310        320        330        340        350        360 
DERMKLVVQA GLFHGNEMLC KTVSSSEVSV CSEPVWKQRL EFDINICDLP RMARLCFALY 

       370        380        390        400        410        420 
AVIEKAKKAR STKKKSKKAD CPIAWANLML FDYKDQLKTG ERCLYMWPSV PDEKGELLNP 

       430        440        450        460        470        480 
TGTVRSNPNT DSAAALLICL PEVAPHPVYY PALEKLPGGM LLASREWRPE LLWMRLHAED 

       490        500        510        520        530        540 
SAPSRMIGVA MPGLGVLPGL VQAPGDAECS RLLQILELGR HSECVHVTEE EQLQLREILE 

       550        560        570        580        590        600 
RRGSGELYEH EKDLVWKLRH EVQEHFPEAL ARLLLVTKWN KHEDVAQMLY LLCSWPELPV 

       610        620        630        640        650        660 
LSALELLDFS FPDCHVGSFA IKSLRKLTDD ELFQYLLQLV QVLKYESYLD CELTKFLLDR 

       670        680        690        700        710        720 
ALANRKIGHF LFWHLRSEMH VPSVALRFGL ILEAYCRGST HHMKVLMKQG EALSKLKALN 

       730        740        750        760        770        780 
DFVKLSSQKT PKPQTKELMH LCMRQEAYLE ALSHLQSPLD PSTLLAEVCV EQCTFMDSKM 

       790        800        810        820        830        840 
KPLWIMYSNE EAGSGGSVGI IFKNGDDLRQ DMLTLQMIQL MDVLWKQEGL DLRMTPYGCL 

       850        860        870        880        890        900 
PTGDRTGLIE VVLRSDTIAN IQLNKSNMAA TAAFNKDALL NWLKSKNPGE ALDRAIEEFT 

       910        920        930        940        950        960 
LSCAGYCVAT YVLGIGDRHS DNIMIRESGQ LFHIDFGHFL GNFKTKFGIN RERVPFILTY 

       970        980        990       1000       1010       1020 
DFVHVIQQGK TNNSEKFERF RGYCERAYTI LRRHGLLFLH LFALMRAAGL PELSCSKDIQ 

      1030       1040       1050       1060 
YLKDSLALGK TEEEALKHFR VKFNEALRES WKTKVNWLAH NVSKDNRQ

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References

[1]Matthews N.
Submitted (JAN-2009) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL691449 Genomic DNA. Translation: CAI15702.1.
IPIIPI00384817.
UniGeneHs.518451

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ5SR50.

Proteomic databases

PRIDEQ5SR50.

Genome annotation databases

EnsemblENST00000361110; ENSP00000354410; ENSG00000171608; Homo sapiens. [Genome view]
UCSCuc001aqe.2. human.

Organism-specific databases

HGNCHGNC:8977. PIK3CD.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ5SR50.
OMAWPELPVL.

Gene expression databases

ArrayExpressQ5SR50.
BgeeQ5SR50.

Family and domain databases

InterProIPR016024. ARM-type_fold.
IPR008973. C2_Ca/lipid-bd_dom_CaLB.
IPR011009. Kinase-like_dom.
IPR000403. PI3/4_kinase_cat.
IPR018936. PI3/4_kinase_CS.
IPR002420. PI3K_C2.
IPR003113. PI3K_p85_bd.
IPR000341. PI3K_ras_bd.
IPR015433. PI_Kinase.
IPR001263. PInositide-3_kin_accessory_dom.
[Graphical view]
Gene3DG3DSA:1.10.1070.11. PI3/4_kinase_cat. 1 hit.
G3DSA:1.25.40.70. PI3Ka. 1 hit.
PANTHERPTHR10048. PI_Kinase. 1 hit.
PfamPF00454. PI3_PI4_kinase. 1 hit.
PF00792. PI3K_C2. 1 hit.
PF02192. PI3K_p85B. 1 hit.
PF00794. PI3K_rbd. 1 hit.
PF00613. PI3Ka. 1 hit.
[Graphical view]
SMARTSM00142. PI3K_C2. 1 hit.
SM00143. PI3K_p85B. 1 hit.
SM00144. PI3K_rbd. 1 hit.
SM00145. PI3Ka. 1 hit.
SM00146. PI3Kc. 1 hit.
[Graphical view]
PROSITEPS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ5SR50_HUMAN
AccessionPrimary (citable) accession number: Q5SR50
Entry history
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: January 19, 2010
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information