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Protein
Submitted name:

Complement receptor type 1

Gene

CR1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Complement receptor type 1Imported
Gene namesi
Name:CR1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000203710.10.
HGNCiHGNC:2334. CR1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei1972 – 1996HelicalSequence analysisAdd BLAST25

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000203710.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 41Sequence analysisAdd BLAST41
ChainiPRO_500426219442 – 2039Sequence analysisAdd BLAST1998

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi43 ↔ 86PROSITE-ProRule annotation
Disulfide bondi266 ↔ 293PROSITE-ProRule annotation
Disulfide bondi297 ↔ 340PROSITE-ProRule annotation
Disulfide bondi326 ↔ 353PROSITE-ProRule annotation
Disulfide bondi493 ↔ 536PROSITE-ProRule annotation
Disulfide bondi716 ↔ 743PROSITE-ProRule annotation
Disulfide bondi747 ↔ 790PROSITE-ProRule annotation
Disulfide bondi776 ↔ 803PROSITE-ProRule annotation
Disulfide bondi943 ↔ 986PROSITE-ProRule annotation
Disulfide bondi1166 ↔ 1193PROSITE-ProRule annotation
Disulfide bondi1197 ↔ 1240PROSITE-ProRule annotation
Disulfide bondi1226 ↔ 1253PROSITE-ProRule annotation
Disulfide bondi1396 ↔ 1439PROSITE-ProRule annotation
Disulfide bondi1619 ↔ 1646PROSITE-ProRule annotation
Disulfide bondi1650 ↔ 1693PROSITE-ProRule annotation
Disulfide bondi1679 ↔ 1706PROSITE-ProRule annotation
Disulfide bondi1848 ↔ 1891PROSITE-ProRule annotation
Disulfide bondi1877 ↔ 1904PROSITE-ProRule annotation
Disulfide bondi1909 ↔ 1952PROSITE-ProRule annotation
Disulfide bondi1938 ↔ 1965PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Proteomic databases

PaxDbiQ5SR44.
PeptideAtlasiQ5SR44.
PRIDEiQ5SR44.

Expressioni

Gene expression databases

BgeeiENSG00000203710.
ExpressionAtlasiQ5SR44. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ5SR44.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 101SushiInterPro annotationAdd BLAST61
Domaini102 – 163SushiInterPro annotationAdd BLAST62
Domaini164 – 234SushiInterPro annotationAdd BLAST71
Domaini236 – 293SushiInterPro annotationAdd BLAST58
Domaini295 – 355SushiInterPro annotationAdd BLAST61
Domaini356 – 418SushiInterPro annotationAdd BLAST63
Domaini419 – 489SushiInterPro annotationAdd BLAST71
Domaini491 – 551SushiInterPro annotationAdd BLAST61
Domaini552 – 613SushiInterPro annotationAdd BLAST62
Domaini614 – 684SushiInterPro annotationAdd BLAST71
Domaini686 – 743SushiInterPro annotationAdd BLAST58
Domaini745 – 805SushiInterPro annotationAdd BLAST61
Domaini806 – 868SushiInterPro annotationAdd BLAST63
Domaini869 – 939SushiInterPro annotationAdd BLAST71
Domaini941 – 1001SushiInterPro annotationAdd BLAST61
Domaini1002 – 1063SushiInterPro annotationAdd BLAST62
Domaini1064 – 1134SushiInterPro annotationAdd BLAST71
Domaini1136 – 1193SushiInterPro annotationAdd BLAST58
Domaini1195 – 1255SushiInterPro annotationAdd BLAST61
Domaini1256 – 1318SushiInterPro annotationAdd BLAST63
Domaini1319 – 1389SushiInterPro annotationAdd BLAST71
Domaini1394 – 1454SushiInterPro annotationAdd BLAST61
Domaini1455 – 1516SushiInterPro annotationAdd BLAST62
Domaini1517 – 1587SushiInterPro annotationAdd BLAST71
Domaini1589 – 1646SushiInterPro annotationAdd BLAST58
Domaini1648 – 1708SushiInterPro annotationAdd BLAST61
Domaini1709 – 1771SushiInterPro annotationAdd BLAST63
Domaini1772 – 1842SushiInterPro annotationAdd BLAST71
Domaini1846 – 1906SushiInterPro annotationAdd BLAST61
Domaini1907 – 1967SushiInterPro annotationAdd BLAST61

Keywords - Domaini

SignalSequence analysis, SushiPROSITE-ProRule annotation, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410KDF5. Eukaryota.
ENOG410YE3Q. LUCA.
GeneTreeiENSGT00760000118803.
HOGENOMiHOG000139590.
HOVERGENiHBG005397.

Family and domain databases

CDDicd00033. CCP. 30 hits.
InterProiView protein in InterPro
IPR000436. Sushi_SCR_CCP_dom.
PfamiView protein in Pfam
PF00084. Sushi. 30 hits.
SMARTiView protein in SMART
SM00032. CCP. 30 hits.
SUPFAMiSSF57535. SSF57535. 30 hits.
PROSITEiView protein in PROSITE
PS50923. SUSHI. 30 hits.

Sequencei

Sequence statusi: Complete.

Q5SR44-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGASSPRSPE PVGPPAPGLP FCCGGSLLAV VVLLALPVAW GQCNAPEWLP
60 70 80 90 100
FARPTNLTDE FEFPIGTYLN YECRPGYSGR PFSIICLKNS VWTGAKDRCR
110 120 130 140 150
RKSCRNPPDP VNGMVHVIKG IQFGSQIKYS CTKGYRLIGS SSATCIISGD
160 170 180 190 200
TVIWDNETPI CDRIPCGLPP TITNGDFIST NRENFHYGSV VTYRCNPGSG
210 220 230 240 250
GRKVFELVGE PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP PNVENGILVS
260 270 280 290 300
DNRSLFSLNE VVEFRCQPGF VMKGPRRVKC QALNKWEPEL PSCSRVCQPP
310 320 330 340 350
PDVLHAERTQ RDKDNFSPGQ EVFYSCEPGY DLRGAASMRC TPQGDWSPAA
360 370 380 390 400
PTCEVKSCDD FMGQLLNGRV LFPVNLQLGA KVDFVCDEGF QLKGSSASYC
410 420 430 440 450
VLAGMESLWN SSVPVCEQIF CPSPPVIPNG RHTGKPLEVF PFGKTVNYTC
460 470 480 490 500
DPHPDRGTSF DLIGESTIRC TSDPQGNGVW SSPAPRCGIL GHCQAPDHFL
510 520 530 540 550
FAKLKTQTNA SDFPIGTSLK YECRPEYYGR PFSITCLDNL VWSSPKDVCK
560 570 580 590 600
RKSCKTPPDP VNGMVHVITD IQVGSRINYS CTTGHRLIGH SSAECILSGN
610 620 630 640 650
AAHWSTKPPI CQRIPCGLPP TIANGDFIST NRENFHYGSV VTYRCNPGSG
660 670 680 690 700
GRKVFELVGE PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP PNVENGILVS
710 720 730 740 750
DNRSLFSLNE VVEFRCQPGF VMKGPRRVKC QALNKWEPEL PSCSRVCQPP
760 770 780 790 800
PDVLHAERTQ RDKDNFSPGQ EVFYSCEPGY DLRGAASMRC TPQGDWSPAA
810 820 830 840 850
PTCEVKSCDD FMGQLLNGRV LFPVNLQLGA KVDFVCDEGF QLKGSSASYC
860 870 880 890 900
VLAGMESLWN SSVPVCEQIF CPSPPVIPNG RHTGKPLEVF PFGKTVNYTC
910 920 930 940 950
DPHPDRGTSF DLIGESTIRC TSDPQGNGVW SSPAPRCGIL GHCQAPDHFL
960 970 980 990 1000
FAKLKTQTNA SDFPIGTSLK YECRPEYYGR PFSITCLDNL VWSSPKDVCK
1010 1020 1030 1040 1050
RKSCKTPPDP VNGMVHVITD IQVGSRINYS CTTGHRLIGH SSAECILSGN
1060 1070 1080 1090 1100
TAHWSTKPPI CQRIPCGLPP TIANGDFIST NRENFHYGSV VTYRCNLGSR
1110 1120 1130 1140 1150
GRKVFELVGE PSIYCTSNDD QVGIWSGPAP QCIIPNKCTP PNVENGILVS
1160 1170 1180 1190 1200
DNRSLFSLNE VVEFRCQPGF VMKGPRRVKC QALNKWEPEL PSCSRVCQPP
1210 1220 1230 1240 1250
PEILHGEHTP SHQDNFSPGQ EVFYSCEPGY DLRGAASLHC TPQGDWSPEA
1260 1270 1280 1290 1300
PRCAVKSCDD FLGQLPHGRV LFPLNLQLGA KVSFVCDEGF RLKGSSVSHC
1310 1320 1330 1340 1350
VLVGMRSLWN NSVPVCEHIF CPNPPAILNG RHTGTPSGDI PYGKEISYTC
1360 1370 1380 1390 1400
DPHPDRGMTF NLIGESTIRC TSDPHGNGVW SSPAPRCELS VRAGHCKTPE
1410 1420 1430 1440 1450
QFPFASPTIP INDFEFPVGT SLNYECRPGY FGKMFSISCL ENLVWSSVED
1460 1470 1480 1490 1500
NCRRKSCGPP PEPFNGMVHI NTDTQFGSTV NYSCNEGFRL IGSPSTTCLV
1510 1520 1530 1540 1550
SGNNVTWDKK APICEIISCE PPPTISNGDF YSNNRTSFHN GTVVTYQCHT
1560 1570 1580 1590 1600
GPDGEQLFEL VGERSIYCTS KDDQVGVWSS PPPRCISTNK CTAPEVENAI
1610 1620 1630 1640 1650
RVPGNRSFFT LTEIIRFRCQ PGFVMVGSHT VQCQTNGRWG PKLPHCSRVC
1660 1670 1680 1690 1700
QPPPEILHGE HTLSHQDNFS PGQEVFYSCE PSYDLRGAAS LHCTPQGDWS
1710 1720 1730 1740 1750
PEAPRCTVKS CDDFLGQLPH GRVLLPLNLQ LGAKVSFVCD EGFRLKGRSA
1760 1770 1780 1790 1800
SHCVLAGMKA LWNSSVPVCE QIFCPNPPAI LNGRHTGTPF GDIPYGKEIS
1810 1820 1830 1840 1850
YACDTHPDRG MTFNLIGESS IRCTSDPQGN GVWSSPAPRC ELSVPAACPH
1860 1870 1880 1890 1900
PPKIQNGHYI GGHVSLYLPG MTISYICDPG YLLVGKGFIF CTDQGIWSQL
1910 1920 1930 1940 1950
DHYCKEVNCS FPLFMNGISK ELEMKKVYHY GDYVTLKCED GYTLEGSPWS
1960 1970 1980 1990 2000
QCQADDRWDP PLAKCTSRTH DALIVGTLSG TIFFILLIIF LSWIILKHRK
2010 2020 2030
GNNAHENPKE VAIHLHSQGG SSVHPRTLQT NEENSRVLP
Length:2,039
Mass (Da):223,707
Last modified:December 21, 2004 - v1
Checksum:i3721172DC2F51412
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137789 Genomic DNA. No translation available.
AL691452 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000367052; ENSP00000356019; ENSG00000203710.
UCSCiuc057ozp.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5SR44_HUMAN
AccessioniPrimary (citable) accession number: Q5SR44
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 27, 2017
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported