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Protein
Submitted name:

SAR1 gene homolog A (S. cerevisiae), isoform CRA_a

Gene

SAR1A

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transportUniRule annotation, Protein transportUniRule annotation, Transport
LigandGTP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
SAR1 gene homolog A (S. cerevisiae), isoform CRA_aImported
Submitted name:
Small GTP-binding proteinImported
Gene namesi
Name:SAR1AImported
ORF Names:hCG_1787550Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000079332.14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Golgi apparatusUniRule annotation

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA34942.

Expressioni

Gene expression databases

BgeeiENSG00000079332.
ExpressionAtlasiQ5SQT9. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ5SQT9. 7 interactors.
MINTiMINT-5003045.

Structurei

3D structure databases

SMRiQ5SQT9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. SAR1 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0077. Eukaryota.
ENOG410YIKI. LUCA.
HOVERGENiHBG104997.
KOiK07953.
OMAiKDDRLAQ.
OrthoDBiEOG091G0KFV.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR006689. Small_GTPase_ARF/SAR.
IPR006687. Small_GTPase_SAR1.
PfamiView protein in Pfam
PF00025. Arf. 1 hit.
PRINTSiPR00328. SAR1GTPBP.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51422. SAR1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5SQT9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFIFEWIYN GFSSVLQFLG LYKKSGKLVF LGLDNAGKTT LLHMLKDDRL
60 70 80 90 100
GQHVPTLHPT SEELTIAGMT FTTFDLGGHE QARRVWKNYL PAINGIVFLV
110 120 130 140 150
DCADHSRLVE SKVELNALMT DETISNVPIL ILGNKIDRTD AISEEKLREI
160 170 180 190
FGLYGQTTGK GNVTLKELNA RPMEVFMCSV LKRQGYGEGF RWLSQYID
Length:198
Mass (Da):22,367
Last modified:May 10, 2005 - v1
Checksum:i38A869175CBA54F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF318066 mRNA. Translation: AAL27183.1.
CH471083 Genomic DNA. Translation: EAW54378.1.
CH471083 Genomic DNA. Translation: EAW54379.1.
RefSeqiNP_001136120.1. NM_001142648.1.
NP_064535.1. NM_020150.4.
UniGeneiHs.499960.

Genome annotation databases

GeneIDi56681.
KEGGihsa:56681.

Similar proteinsi

Entry informationi

Entry nameiQ5SQT9_HUMAN
AccessioniPrimary (citable) accession number: Q5SQT9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 27, 2017
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.