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Q5SQT9

- Q5SQT9_HUMAN

UniProt

Q5SQT9 - Q5SQT9_HUMAN

Protein
Submitted name:

SAR1 gene homolog A (S. cerevisiae), isoform CRA_a

Gene

SAR1A

Organism
Homo sapiens (Human)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 93 (01 Oct 2014)
      Sequence version 1 (10 May 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-KW

    GO - Biological processi

    1. intracellular protein transport Source: InterPro
    2. vesicle-mediated transport Source: UniProtKB-KW

    Keywords - Biological processi

    ER-Golgi transportUniRule annotation, Protein transportUniRule annotation, Transport

    Keywords - Ligandi

    GTP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    SAR1 gene homolog A (S. cerevisiae), isoform CRA_aImported
    Submitted name:
    Small GTP-binding proteinImported
    Gene namesi
    Name:SAR1AImported
    ORF Names:hCG_1787550Imported
    OrganismiHomo sapiens (Human)Imported
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

    Subcellular locationi

    GO - Cellular componenti

    1. Golgi apparatus Source: UniProtKB-KW
    2. sarcoplasmic reticulum Source: Ensembl

    Keywords - Cellular componenti

    Endoplasmic reticulumUniRule annotation, Golgi apparatusUniRule annotation

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA34942.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-5003045.

    Structurei

    3D structure databases

    SMRiQ5SQT9. Positions 14-198.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the small GTPase superfamily. SAR1 family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG104997.
    KOiK07953.
    OMAiQQARRIW.
    PhylomeDBiQ5SQT9.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR006689. Small_GTPase_ARF/SAR.
    IPR006687. Small_GTPase_SAR1.
    [Graphical view]
    PfamiPF00025. Arf. 1 hit.
    [Graphical view]
    PRINTSiPR00328. SAR1GTPBP.
    SMARTiSM00178. SAR. 1 hit.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 1 hit.
    TIGRFAMsiTIGR00231. small_GTP. 1 hit.
    PROSITEiPS51422. SAR1. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q5SQT9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSFIFEWIYN GFSSVLQFLG LYKKSGKLVF LGLDNAGKTT LLHMLKDDRL    50
    GQHVPTLHPT SEELTIAGMT FTTFDLGGHE QARRVWKNYL PAINGIVFLV 100
    DCADHSRLVE SKVELNALMT DETISNVPIL ILGNKIDRTD AISEEKLREI 150
    FGLYGQTTGK GNVTLKELNA RPMEVFMCSV LKRQGYGEGF RWLSQYID 198
    Length:198
    Mass (Da):22,367
    Last modified:May 10, 2005 - v1
    Checksum:i38A869175CBA54F3
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF318066 mRNA. Translation: AAL27183.1.
    CH471083 Genomic DNA. Translation: EAW54378.1.
    CH471083 Genomic DNA. Translation: EAW54379.1.
    RefSeqiNP_001136120.1. NM_001142648.1.
    NP_064535.1. NM_020150.4.
    UniGeneiHs.499960.

    Genome annotation databases

    GeneIDi56681.
    KEGGihsa:56681.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF318066 mRNA. Translation: AAL27183.1 .
    CH471083 Genomic DNA. Translation: EAW54378.1 .
    CH471083 Genomic DNA. Translation: EAW54379.1 .
    RefSeqi NP_001136120.1. NM_001142648.1.
    NP_064535.1. NM_020150.4.
    UniGenei Hs.499960.

    3D structure databases

    SMRi Q5SQT9. Positions 14-198.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-5003045.

    Protocols and materials databases

    DNASUi 56681.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 56681.
    KEGGi hsa:56681.

    Organism-specific databases

    CTDi 56681.
    PharmGKBi PA34942.

    Phylogenomic databases

    HOVERGENi HBG104997.
    KOi K07953.
    OMAi QQARRIW.
    PhylomeDBi Q5SQT9.

    Miscellaneous databases

    ChiTaRSi SAR1A. human.
    GenomeRNAii 56681.
    NextBioi 62187.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR027417. P-loop_NTPase.
    IPR005225. Small_GTP-bd_dom.
    IPR006689. Small_GTPase_ARF/SAR.
    IPR006687. Small_GTPase_SAR1.
    [Graphical view ]
    Pfami PF00025. Arf. 1 hit.
    [Graphical view ]
    PRINTSi PR00328. SAR1GTPBP.
    SMARTi SM00178. SAR. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 1 hit.
    TIGRFAMsi TIGR00231. small_GTP. 1 hit.
    PROSITEi PS51422. SAR1. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Identification of a Hydroxyurea-Inducible Small GTP-Binding Protein Associated with Elevated Gamma Globin Gene Expression."
      Tang D.C., Zhu J., Liu W., Sun J.F., Rodgers G.P.
      Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: Bone marrowImported.
    2. "The sequence of the human genome."
      Venter J.C., Adams M.D., Myers E.W., Li P.W., Mural R.J., Sutton G.G., Smith H.O., Yandell M., Evans C.A., Holt R.A., Gocayne J.D., Amanatides P., Ballew R.M., Huson D.H., Wortman J.R., Zhang Q., Kodira C.D., Zheng X.H.
      , Chen L., Skupski M., Subramanian G., Thomas P.D., Zhang J., Gabor Miklos G.L., Nelson C., Broder S., Clark A.G., Nadeau J., McKusick V.A., Zinder N., Levine A.J., Roberts R.J., Simon M., Slayman C., Hunkapiller M., Bolanos R., Delcher A., Dew I., Fasulo D., Flanigan M., Florea L., Halpern A., Hannenhalli S., Kravitz S., Levy S., Mobarry C., Reinert K., Remington K., Abu-Threideh J., Beasley E., Biddick K., Bonazzi V., Brandon R., Cargill M., Chandramouliswaran I., Charlab R., Chaturvedi K., Deng Z., Di Francesco V., Dunn P., Eilbeck K., Evangelista C., Gabrielian A.E., Gan W., Ge W., Gong F., Gu Z., Guan P., Heiman T.J., Higgins M.E., Ji R.R., Ke Z., Ketchum K.A., Lai Z., Lei Y., Li Z., Li J., Liang Y., Lin X., Lu F., Merkulov G.V., Milshina N., Moore H.M., Naik A.K., Narayan V.A., Neelam B., Nusskern D., Rusch D.B., Salzberg S., Shao W., Shue B., Sun J., Wang Z., Wang A., Wang X., Wang J., Wei M., Wides R., Xiao C., Yan C., Yao A., Ye J., Zhan M., Zhang W., Zhang H., Zhao Q., Zheng L., Zhong F., Zhong W., Zhu S., Zhao S., Gilbert D., Baumhueter S., Spier G., Carter C., Cravchik A., Woodage T., Ali F., An H., Awe A., Baldwin D., Baden H., Barnstead M., Barrow I., Beeson K., Busam D., Carver A., Center A., Cheng M.L., Curry L., Danaher S., Davenport L., Desilets R., Dietz S., Dodson K., Doup L., Ferriera S., Garg N., Gluecksmann A., Hart B., Haynes J., Haynes C., Heiner C., Hladun S., Hostin D., Houck J., Howland T., Ibegwam C., Johnson J., Kalush F., Kline L., Koduru S., Love A., Mann F., May D., McCawley S., McIntosh T., McMullen I., Moy M., Moy L., Murphy B., Nelson K., Pfannkoch C., Pratts E., Puri V., Qureshi H., Reardon M., Rodriguez R., Rogers Y.H., Romblad D., Ruhfel B., Scott R., Sitter C., Smallwood M., Stewart E., Strong R., Suh E., Thomas R., Tint N.N., Tse S., Vech C., Wang G., Wetter J., Williams S., Williams M., Windsor S., Winn-Deen E., Wolfe K., Zaveri J., Zaveri K., Abril J.F., Guigo R., Campbell M.J., Sjolander K.V., Karlak B., Kejariwal A., Mi H., Lazareva B., Hatton T., Narechania A., Diemer K., Muruganujan A., Guo N., Sato S., Bafna V., Istrail S., Lippert R., Schwartz R., Walenz B., Yooseph S., Allen D., Basu A., Baxendale J., Blick L., Caminha M., Carnes-Stine J., Caulk P., Chiang Y.H., Coyne M., Dahlke C., Mays A., Dombroski M., Donnelly M., Ely D., Esparham S., Fosler C., Gire H., Glanowski S., Glasser K., Glodek A., Gorokhov M., Graham K., Gropman B., Harris M., Heil J., Henderson S., Hoover J., Jennings D., Jordan C., Jordan J., Kasha J., Kagan L., Kraft C., Levitsky A., Lewis M., Liu X., Lopez J., Ma D., Majoros W., McDaniel J., Murphy S., Newman M., Nguyen T., Nguyen N., Nodell M., Pan S., Peck J., Peterson M., Rowe W., Sanders R., Scott J., Simpson M., Smith T., Sprague A., Stockwell T., Turner R., Venter E., Wang M., Wen M., Wu D., Wu M., Xia A., Zandieh A., Zhu X.
      Science 291:1304-1351(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
    3. Cited for: NUCLEOTIDE SEQUENCE.

    Entry informationi

    Entry nameiQ5SQT9_HUMAN
    AccessioniPrimary (citable) accession number: Q5SQT9
    Entry historyi
    Integrated into UniProtKB/TrEMBL: May 10, 2005
    Last sequence update: May 10, 2005
    Last modified: October 1, 2014
    This is version 93 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.