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Protein
Submitted name:

C-terminal-binding protein 2

Gene

CTBP2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
C-terminal-binding protein 2Imported
Gene namesi
Name:CTBP2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

HGNCiHGNC:2495. CTBP2.

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000175029.

PTM / Processingi

Proteomic databases

EPDiQ5SQP8.
MaxQBiQ5SQP8.
PaxDbiQ5SQP8.
PeptideAtlasiQ5SQP8.
PRIDEiQ5SQP8.

Expressioni

Gene expression databases

BgeeiENSG00000175029.
ExpressionAtlasiQ5SQP8. baseline and differential.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
CACNB3P542844EBI-11742664,EBI-1184651
FHL3Q136434EBI-11742664,EBI-741101

Protein-protein interaction databases

IntActiQ5SQP8. 23 interactors.
MINTiMINT-1435295.
STRINGi9606.ENSP00000311825.

Structurei

3D structure databases

ProteinModelPortaliQ5SQP8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini112 – 4262-Hacid_dhInterPro annotationAdd BLAST315
Domaini208 – 3912-Hacid_dh_CInterPro annotationAdd BLAST184

Phylogenomic databases

eggNOGiKOG0067. Eukaryota.
COG0111. LUCA.
GeneTreeiENSGT00530000063021.
HOGENOMiHOG000136701.
HOVERGENiHBG001898.
OMAiVGRIPDC.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SQP8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPGLPGPTG LCAQTSSRGQ KSVLKQKESC GIWQLYHFLS RKQEPRWEPC
60 70 80 90 100
VSGSSSGDGA VADLADELRG YPALCCTLPV HSYRSWAGIR PQIMNGPLHP
110 120 130 140 150
RPLVALLDGR DCTVEMPILK DLATVAFCDA QSTQEIHEKV LNEAVGAMMY
160 170 180 190 200
HTITLTREDL EKFKALRVIV RIGSGYDNVD IKAAGELGIA VCNIPSAAVE
210 220 230 240 250
ETADSTICHI LNLYRRNTWL YQALREGTRV QSVEQIREVA SGAARIRGET
260 270 280 290 300
LGLIGFGRTG QAVAVRAKAF GFSVIFYDPY LQDGIERSLG VQRVYTLQDL
310 320 330 340 350
LYQSDCVSLH CNLNEHNHHL INDFTIKQMR QGAFLVNAAR GGLVDEKALA
360 370 380 390 400
QALKEGRIRG AALDVHESEP FSFAQGPLKD APNLICTPHT AWYSEQASLE
410 420 430 440 450
MREAAATEIR RAITGRIPES LRNCVNKEFF VTSAPWSVID QQAIHPELNG
460 470 480 490 500
ATYRYPPGIV GVAPGGLPAA MEGIIPGGIP VTHNLPTVAH PSQAPSPNQP
510
TKHGDNREHP NEQ
Length:513
Mass (Da):56,102
Last modified:December 21, 2004 - v1
Checksum:iA7A54EB7F0F34922
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157888 Genomic DNA. No translation available.
AL596261 Genomic DNA. No translation available.
AL731571 Genomic DNA. No translation available.
RefSeqiXP_011537651.1. XM_011539349.2.
UniGeneiHs.501345.

Genome annotation databases

EnsembliENST00000334808; ENSP00000357816; ENSG00000175029.
GeneIDi1488.
UCSCiuc001lid.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL157888 Genomic DNA. No translation available.
AL596261 Genomic DNA. No translation available.
AL731571 Genomic DNA. No translation available.
RefSeqiXP_011537651.1. XM_011539349.2.
UniGeneiHs.501345.

3D structure databases

ProteinModelPortaliQ5SQP8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ5SQP8. 23 interactors.
MINTiMINT-1435295.
STRINGi9606.ENSP00000311825.

Proteomic databases

EPDiQ5SQP8.
MaxQBiQ5SQP8.
PaxDbiQ5SQP8.
PeptideAtlasiQ5SQP8.
PRIDEiQ5SQP8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000334808; ENSP00000357816; ENSG00000175029.
GeneIDi1488.
UCSCiuc001lid.5. human.

Organism-specific databases

CTDi1488.
HGNCiHGNC:2495. CTBP2.
OpenTargetsiENSG00000175029.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG0067. Eukaryota.
COG0111. LUCA.
GeneTreeiENSGT00530000063021.
HOGENOMiHOG000136701.
HOVERGENiHBG001898.
OMAiVGRIPDC.

Miscellaneous databases

ChiTaRSiCTBP2. human.
GenomeRNAii1488.

Gene expression databases

BgeeiENSG00000175029.
ExpressionAtlasiQ5SQP8. baseline and differential.

Family and domain databases

Gene3Di3.40.50.720. 2 hits.
InterProiIPR006139. D-isomer_2_OHA_DH_cat_dom.
IPR029753. D-isomer_DH_CS.
IPR006140. D-isomer_DH_NAD-bd.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
PfamiPF00389. 2-Hacid_dh. 1 hit.
PF02826. 2-Hacid_dh_C. 1 hit.
[Graphical view]
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00671. D_2_HYDROXYACID_DH_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SQP8_HUMAN
AccessioniPrimary (citable) accession number: Q5SQP8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 30, 2016
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.Imported

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.