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Protein
Submitted name:

Homeodomain-interacting protein kinase 1

Gene

HIPK1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

SignaLinkiQ5SQL3.

Names & Taxonomyi

Protein namesi
Submitted name:
Homeodomain-interacting protein kinase 10 Publication
Gene namesi
Name:HIPK10 Publication
OrganismiHomo sapiens (Human)0 Publication
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 1

Organism-specific databases

EuPathDBiHostDB:ENSG00000163349.21.
HGNCiHGNC:19006. HIPK1.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000163349.

PTM / Processingi

Proteomic databases

MaxQBiQ5SQL3.

Expressioni

Gene expression databases

BgeeiENSG00000163349.
ExpressionAtlasiQ5SQL3. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini190 – 518Protein kinaseImportedAdd BLAST329

Phylogenomic databases

eggNOGiKOG0667. Eukaryota.
ENOG410XPET. LUCA.
GeneTreeiENSGT00760000119032.
HOGENOMiHOG000231785.
HOVERGENiHBG051908.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom_sf.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5SQL3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASQLQVFSP PSVSSSAFCS AKKLKIEPSG WDVSGQSSND KYYTHSKTLP
60 70 80 90 100
ATQGQANSSH QVANFNIPAY DQGLLLPAPA VEHIVVTAAD SSGSAATSTF
110 120 130 140 150
QSSQTLTHRS NVSLLEPYQK CGLKRKSEEV DSNGSVQIIE EHPPLMLQNR
160 170 180 190 200
TVVGAAATTT TVTTKSSSSS GEGDYQLVQH EILCSMTNSY EVLEFLGRGT
210 220 230 240 250
FGQVAKCWKR STKEIVAIKI LKNHPSYARQ GQIEVSILSR LSSENADEYN
260 270 280 290 300
FVRSYECFQH KNHTCLVFEM LEQNLYDFLK QNKFSPLPLK YIRPILQQVA
310 320 330 340 350
TALMKLKSLG LIHADLKPEN IMLVDPVRQP YRVKVIDFGS ASHVSKAVCS
360 370 380 390 400
TYLQSRYYRA PEIILGLPFC EAIDMWSLGC VIAELFLGWP LYPGASEYDQ
410 420 430 440 450
IRYISQTQGL PAEYLLSAGT KTTRFFNRDP NLGYPLWRLK TPEEHELETG
460 470 480 490 500
IKSKEARKYI FNCLDDMAQV NMSTDLEGTD MLAEKADRRE YIDLLKKMLT
510 520 530 540 550
IDADKRITPL KTLNHQFVTM THLLDFPHSN HVKSCFQNME ICKRRVHMYD
560 570 580 590 600
TVSQIKSPFT THVAPNTSTN LTMSFSNQLN TVHNQASVLA SSSTAAAATL
610 620 630 640 650
SLANSDVSLL NYQSALYPSS AAPVPGVAQQ GVSLQPGTTQ ICTQTDPFQQ
660 670 680 690 700
TFIVCPPAFQ TGLQATTKHS GFPVRMDNAV PIVPQAPAAQ PLQIQSGVLT
710 720 730 740 750
QQAWPGGTQQ ILLPSTWQQL PGVALHNSVQ PTAMIPEAMG SGQQLADWRN
760 770 780 790 800
AHSHGNQYST IMQQPSLLTN HVTLATAQPL NVGVAHVVRQ QQSSSLPSKK
810 820 830 840 850
NKQSAPVSSK SSLDVLPSQV YSLVGSSPLR TTSSYNSLVP VQDQHQPIII
860 870 880 890 900
PDTPSPPVSV ITIRSDTDEE EDNKYKPSSS GLKPRSNVIS YVTVNDSPDS
910 920 930 940 950
DSSLSSPYST DTLSALRGNS GSVLEGPGRV VADGTGTRTI IVPPLKTQLG
960 970 980 990 1000
DCTVATQASG LLSNKTKPVA SVSGQSSGCC ITPTGYRAQR GGTSAAQPLN
1010 1020 1030 1040 1050
LSQNQQSSAA PTSQERSSNP APRRQQAFVA PLSQAPYTFQ HGSPLHSTGH
1060 1070 1080 1090 1100
PHLAPAPAHL PSQAHLYTYA APTSAAALGS TSSIAHLFSP QGSSRHAAAY
1110 1120 1130 1140 1150
TTHPSTLVHQ VPVSVGPSLL TSASVAPAQY QHQFATQSYI GSSRGSTIYT
1160
GYPLSPTKIS QYSYL
Length:1,165
Mass (Da):126,264
Last modified:December 21, 2004 - v1
Checksum:i0BF6F926C60489AD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL137856 Genomic DNA. No translation available.
AL731797 Genomic DNA. No translation available.

Genome annotation databases

EnsembliENST00000369555; ENSP00000358568; ENSG00000163349.
ENST00000626993; ENSP00000486090; ENSG00000163349.
UCSCiuc057joy.1. human.

Similar proteinsi

Entry informationi

Entry nameiQ5SQL3_HUMAN
AccessioniPrimary (citable) accession number: Q5SQL3
Secondary accession number(s): A6NDY4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 22, 2017
This is version 120 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.0 Publication

Keywords - Technical termi

Complete proteome, Proteomics identificationIEA:, Reference proteome0 Publication