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Protein
Submitted name:

Calcium-activated potassium channel subunit beta-1

Gene

Kcnmb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  • calcium-activated potassium channel activity Source: MGI
  • potassium channel regulator activity Source: GO_Central

GO - Biological processi

  • detection of calcium ion Source: GO_Central
  • potassium ion transmembrane transport Source: GOC
  • synaptic transmission Source: GO_Central
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_311531. cGMP effects.
REACT_315822. Ca2+ activated K+ channels.

Names & Taxonomyi

Protein namesi
Submitted name:
Calcium-activated potassium channel subunit beta-1Imported
Submitted name:
Potassium large conductance calcium-activated channel, subfamily M, beta member 1Imported
Gene namesi
Name:Kcnmb1Imported
ORF Names:mCG_6672Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:1334203. Kcnmb1.

Subcellular locationi

GO - Cellular componenti

  • integral component of membrane Source: MGI
  • voltage-gated potassium channel complex Source: MGI
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020362.

Family & Domainsi

Phylogenomic databases

GeneTreeiENSGT00390000015997.
HOVERGENiHBG052223.
KOiK04937.
OMAiRDRNQQC.
OrthoDBiEOG77WWDC.
TreeFamiTF328589.

Family and domain databases

InterProiIPR003930. K_chnl_Ca-activ_BK_bsu.
[Graphical view]
PANTHERiPTHR10258. PTHR10258. 1 hit.
PfamiPF03185. CaKB. 1 hit.
[Graphical view]
PRINTSiPR01450. BKCHANNELB.

Sequencei

Sequence statusi: Complete.

Q5SQK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKKLVMAQK RGETRALCLG VAMVVCAAIT YYVLGTTVLP LYQKSVWTQE
60 70 80 90 100
SICHLIETNI KDQEELEGKK VPQYPCLWVN VSAVGRWAML YHTEDTRDQN
110 120 130 140 150
QQCSYIPRNL DNYQTALADV KKVRANFYKH HEFYCLSAPQ VNETSVVYQR
160 170 180 190
LYGPQVLLFS FFWPTFLLTG GLILIAMVKL NRSLSILAAQ K
Length:191
Mass (Da):21,846
Last modified:May 10, 2005 - v1
Checksum:iABDD40E43EA74AB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL731867 Genomic DNA. No translation available.
CH466604 Genomic DNA. Translation: EDL23733.1.
RefSeqiNP_112446.2. NM_031169.4.
XP_006514604.1. XM_006514541.2.
UniGeneiMm.6206.

Genome annotation databases

EnsembliENSMUST00000020362; ENSMUSP00000020362; ENSMUSG00000020155.
GeneIDi16533.
KEGGimmu:16533.
UCSCiuc007iks.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL731867 Genomic DNA. No translation available.
CH466604 Genomic DNA. Translation: EDL23733.1.
RefSeqiNP_112446.2. NM_031169.4.
XP_006514604.1. XM_006514541.2.
UniGeneiMm.6206.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000020362.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000020362; ENSMUSP00000020362; ENSMUSG00000020155.
GeneIDi16533.
KEGGimmu:16533.
UCSCiuc007iks.2. mouse.

Organism-specific databases

CTDi3779.
MGIiMGI:1334203. Kcnmb1.

Phylogenomic databases

GeneTreeiENSGT00390000015997.
HOVERGENiHBG052223.
KOiK04937.
OMAiRDRNQQC.
OrthoDBiEOG77WWDC.
TreeFamiTF328589.

Enzyme and pathway databases

ReactomeiREACT_311531. cGMP effects.
REACT_315822. Ca2+ activated K+ channels.

Miscellaneous databases

NextBioi289953.
SOURCEiSearch...

Family and domain databases

InterProiIPR003930. K_chnl_Ca-activ_BK_bsu.
[Graphical view]
PANTHERiPTHR10258. PTHR10258. 1 hit.
PfamiPF03185. CaKB. 1 hit.
[Graphical view]
PRINTSiPR01450. BKCHANNELB.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ5SQK1_MOUSE
AccessioniPrimary (citable) accession number: Q5SQK1
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: July 22, 2015
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.