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Protein
Submitted name:

Neuroepithelial cell transforming gene 1, isoform CRA_a

Gene

NET1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGuanine-nucleotide releasing factorSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Neuroepithelial cell transforming gene 1, isoform CRA_aImported
Submitted name:
cDNA, FLJ96638, Homo sapiens neuroepithelial cell transforming gene 1 (NET1), mRNAImported
Gene namesi
Name:NET1Imported
ORF Names:hCG_19072Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000173848.18.

Subcellular locationi

PTM / Processingi

Proteomic databases

MaxQBiQ5SQI7.

Expressioni

Gene expression databases

BgeeiENSG00000173848.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiQ5SQI7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini120 – 302DHInterPro annotationAdd BLAST183
Domaini332 – 447PHInterPro annotationAdd BLAST116

Phylogenomic databases

eggNOGiKOG4305. Eukaryota.
COG5422. LUCA.
HOGENOMiHOG000034044.
HOVERGENiHBG050567.

Family and domain databases

CDDicd00160. RhoGEF. 1 hit.
Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiView protein in InterPro
IPR035899. DBL_dom_sf.
IPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR011993. PH-like_dom_sf.
IPR001849. PH_domain.
PfamiView protein in Pfam
PF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
SMARTiView protein in SMART
SM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50729. SSF50729. 1 hit.
PROSITEiView protein in PROSITE
PS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5SQI7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVAHDETGGL LPIKRTIRVL DVNNQSFREQ EEPSNKRVRP LARVTSLANL
60 70 80 90 100
ISPVRNGAVR RFGQTIQSFT LRGDHRSPAS AQKFSSRSTV PTPAKRRSSA
110 120 130 140 150
LWSEMLDITM KESLTTREIR RQEAIYEMSR GEQDLIEDLK LARKAYHDPM
160 170 180 190 200
LKLSIMSEEE LTHIFGDLDS YIPLHEDLLT RIGEATKPDG TVEQIGHILV
210 220 230 240 250
SWLPRLNAYR GYCSNQLAAK ALLDQKKQDP RVQDFLQRCL ESPFSRKLDL
260 270 280 290 300
WSFLDIPRSR LVKYPLLLKE ILKHTPKEHP DVQLLEDAIL IIQGVLSDIN
310 320 330 340 350
LKKGESECQY YIDKLEYLDE KQRDPRIEAS KVLLCHGELR SKSGHKLYIF
360 370 380 390 400
LFQDILVLTR PVTRNERHSY QVYRQPIPVQ ELVLEDLQDG DVRMGGSFRG
410 420 430 440 450
AFSNSEKAKN IFRIRFHDPS PAQSHTLQAN DVFHKQQWFN CIRAAIAPFQ
460 470 480 490 500
SAGSPPELQG LPELHEECEG NHPSARKLTA QRRASTVSSV TQVEVDENAY
510 520 530 540
RCGSGMQMAE DSKSLKTHQT QPGIRRARDK ALSGGKRKET LV
Length:542
Mass (Da):61,885
Last modified:May 10, 2005 - v1
Checksum:i770F252F0FCA7E92
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315566 mRNA. Translation: BAG37941.1.
CH471072 Genomic DNA. Translation: EAW86445.1.
RefSeqiNP_005854.2. NM_005863.4.
UniGeneiHs.25155.

Genome annotation databases

GeneIDi10276.

Similar proteinsi

Entry informationi

Entry nameiQ5SQI7_HUMAN
AccessioniPrimary (citable) accession number: Q5SQI7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: November 22, 2017
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.