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Protein
Submitted name:

Neuroepithelial cell transforming gene 1, isoform CRA_b

Gene

NET1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Neuroepithelial cell transforming gene 1, isoform CRA_bImported
Submitted name:
cDNA FLJ50843, highly similar to Neuroepithelial cell-transforming gene 1 proteinImported
Gene namesi
Name:NET1Imported
ORF Names:hCG_19072Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Proteomic databases

MaxQBiQ5SQI5.

Expressioni

Gene expression databases

BgeeiENSG00000173848.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000347134.

Structurei

3D structure databases

SMRiQ5SQI5. Positions 157-501.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini174 – 356183DH (DBL-homology)InterPro annotationAdd
BLAST
Domaini386 – 501116PHInterPro annotationAdd
BLAST

Sequence similaritiesi

Contains 1 PH domain.UniRule annotation
Contains DH (DBL-homology) domain.SAAS annotation

Phylogenomic databases

eggNOGiKOG4305. Eukaryota.
COG5422. LUCA.
HOVERGENiHBG050567.
OMAiGPNWDFT.
OrthoDBiEOG091G05S7.
PhylomeDBiQ5SQI5.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50729. SSF50729. 1 hit.
PROSITEiPS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SQI5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPELAAQKQ PRPRRRSRRA SGLSTEGATG PSADTSGSEL DGRCSLRRGS
60 70 80 90 100
SFTFLTPGPN WDFTLKRKRR EKDDDVVSLS SLDLKEPSNK RVRPLARVTS
110 120 130 140 150
LANLISPVRN GAVRRFGQTI QSFTLRGDHR SPASAQKFSS RSTVPTPAKR
160 170 180 190 200
RSSALWSEML DITMKESLTT REIRRQEAIY EMSRGEQDLI EDLKLARKAY
210 220 230 240 250
HDPMLKLSIM SEEELTHIFG DLDSYIPLHE DLLTRIGEAT KPDGTVEQIG
260 270 280 290 300
HILVSWLPRL NAYRGYCSNQ LAAKALLDQK KQDPRVQDFL QRCLESPFSR
310 320 330 340 350
KLDLWSFLDI PRSRLVKYPL LLKEILKHTP KEHPDVQLLE DAILIIQGVL
360 370 380 390 400
SDINLKKGES ECQYYIDKLE YLDEKQRDPR IEASKVLLCH GELRSKSGHK
410 420 430 440 450
LYIFLFQDIL VLTRPVTRNE RHSYQVYRQP IPVQELVLED LQDGDVRMGG
460 470 480 490 500
SFRGAFSNSE KAKNIFRIRF HDPSPAQSHT LQANDVFHKQ QWFNCIRAAI
510 520 530 540 550
APFQSAGSPP ELQGLPELHE ECEGNHPSAR KLTAQRRAST VSSVTQVEVD
560 570 580 590
ENAYRCGSGM QMAEDSKSLK THQTQPGIRR ARDKALSGGK RKETLV
Length:596
Mass (Da):67,740
Last modified:May 10, 2005 - v1
Checksum:iE1AD964F14650D2C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK299335 mRNA. Translation: BAG61338.1.
CH471072 Genomic DNA. Translation: EAW86446.1.
RefSeqiNP_001040625.1. NM_001047160.2.
UniGeneiHs.25155.

Genome annotation databases

GeneIDi10276.
KEGGihsa:10276.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK299335 mRNA. Translation: BAG61338.1.
CH471072 Genomic DNA. Translation: EAW86446.1.
RefSeqiNP_001040625.1. NM_001047160.2.
UniGeneiHs.25155.

3D structure databases

SMRiQ5SQI5. Positions 157-501.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000347134.

Proteomic databases

MaxQBiQ5SQI5.

Protocols and materials databases

DNASUi10276.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi10276.
KEGGihsa:10276.

Organism-specific databases

CTDi10276.

Phylogenomic databases

eggNOGiKOG4305. Eukaryota.
COG5422. LUCA.
HOVERGENiHBG050567.
OMAiGPNWDFT.
OrthoDBiEOG091G05S7.
PhylomeDBiQ5SQI5.

Miscellaneous databases

ChiTaRSiNET1. human.
GenomeRNAii10276.

Gene expression databases

BgeeiENSG00000173848.

Family and domain databases

Gene3Di1.20.900.10. 1 hit.
2.30.29.30. 1 hit.
InterProiIPR000219. DH-domain.
IPR001331. GDS_CDC24_CS.
IPR011993. PH_dom-like.
IPR001849. PH_domain.
[Graphical view]
PfamiPF00169. PH. 1 hit.
PF00621. RhoGEF. 1 hit.
[Graphical view]
SMARTiSM00233. PH. 1 hit.
SM00325. RhoGEF. 1 hit.
[Graphical view]
SUPFAMiSSF48065. SSF48065. 1 hit.
SSF50729. SSF50729. 1 hit.
PROSITEiPS00741. DH_1. 1 hit.
PS50010. DH_2. 1 hit.
PS50003. PH_DOMAIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SQI5_HUMAN
AccessioniPrimary (citable) accession number: Q5SQI5
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.