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Protein
Submitted name:

Transducin-like enhancer protein 1

Gene

Tle1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Transducin-like enhancer protein 1Imported
Gene namesi
Name:Tle1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:104636 Tle1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

MaxQBiQ5SQA4
PRIDEiQ5SQA4

Expressioni

Gene expression databases

BgeeiENSMUSG00000008305
ExpressionAtlasiQ5SQA4 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5SQA4
SMRiQ5SQA4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini487 – 660WD_REPEATS_REGIONInterPro annotationAdd BLAST174
Repeati577 – 618WDPROSITE-ProRule annotationAdd BLAST42
Repeati619 – 660WDPROSITE-ProRule annotationAdd BLAST42
Domaini701 – 777WD_REPEATS_REGIONInterPro annotationAdd BLAST77

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili34 – 61Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0639 Eukaryota
ENOG410XPX3 LUCA
GeneTreeiENSGT00550000074465
HOGENOMiHOG000293211
HOVERGENiHBG004689

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR005617 Groucho/TLE_N
IPR009146 Groucho_enhance
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF03920 TLE_N, 1 hit
PF00400 WD40, 2 hits
PRINTSiPR01850 GROUCHOFAMLY
SMARTiView protein in SMART
SM00320 WD40, 7 hits
SUPFAMiSSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 2 hits
PS50294 WD_REPEATS_REGION, 2 hits

Sequencei

Sequence statusi: Complete.

Q5SQA4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFPQSRHPVP HAGHLQTPHQ AAGQPFKFTI PESLDRIKEE FQFLQAQYHS
60 70 80 90 100
LKLECEKLAS EKTEMQRHYV MYYEMSYGLN IEMHKQTEIA KRLNTICAQV
110 120 130 140 150
IPFLSQEHQQ QVAQAVERAK QVTMAELNAI IGQQQLQAQH LSHGHGPPVP
160 170 180 190 200
LTPHPSGLQP PGIPPLGGSA SLLALSSALS GQSHLAIKDD KKHHDAERHR
210 220 230 240 250
DREPGTSNSL LVPDSLRGTD KRRNGPEFSS DIKKRKVDDK DNYDSDGDKS
260 270 280 290 300
DDNLVVDVSN EDPSSPHASP THSPRENGID KNRLLKKDAS GSPASTASSG
310 320 330 340 350
SSSSLKSKEV SLHEKANTPV LKSSTPTPRS DMPTPGTSAT PGLRPGLGKP
360 370 380 390 400
PAMEPLVNQA AGLRTPLAVP GPYPAPFGMV PHAGMNGELT SPGAAYAGLH
410 420 430 440 450
SMSPQMSAAA AAAAAAVVAY GRSPMVGFDP PPHMRVPSIP PNLAGIPGGK
460 470 480 490 500
PAYSFHVTAD GQMQPVPFPP DALIGPGIPR HARQINTLNH GEVVCAVTIS
510 520 530 540 550
NPTRHVYTGG KGCVKVWDIS HPGNKSPVSQ LDCLNRDNYI RSCKLLPDGC
560 570 580 590 600
TLIVGGEAST LSIWDLAAPT PRIKAELTSS APACYALAIS PDSKVCFSCC
610 620 630 640 650
SDGNIAVWDL HNQTLVRQFQ GHTDGASCID ISNDGTKLWT GGLDNTVRSW
660 670 680 690 700
DLREGRQLQQ HDFTSQIFSL GYCPTGEWLA VGMESSNVEV LHVNKPDKYQ
710 720 730 740 750
LHLHESCVLS LKFAYCGKWF VSTGKDNLLN AWRTPYGASI FQSKESSSVL
760 770
SCDISVDDKY IVTGSGDKKA TVYEVIY
Length:777
Mass (Da):83,846
Last modified:December 21, 2004 - v1
Checksum:iD3C8013E4235903A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL773513 Genomic DNA No translation available.
BX640475 Genomic DNA No translation available.
RefSeqiXP_006537823.1, XM_006537760.2
UniGeneiMm.278444
Mm.388819
Mm.399716

Genome annotation databases

EnsembliENSMUST00000102848; ENSMUSP00000099912; ENSMUSG00000008305
GeneIDi21885
UCSCiuc008tie.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ5SQA4_MOUSE
AccessioniPrimary (citable) accession number: Q5SQA4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: May 23, 2018
This is version 127 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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