Unreviewed, UniProtKB/TrEMBL Q5SQ95 (Q5SQ95_HUMAN)

Names and origin

Protein names

Submitted name:
    Valyl-tRNA synthetase 2-like EMBL CAI18454.1

Gene names

Name:	VARS2L EMBL CAI18454.1
ORF Names:	DAQB-11J22.1-002 EMBL CAI18454.1

Organism

Homo sapiens (Human) EMBL CAI18454.1

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

Protein attributes

Sequence length	993 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family. RuleBase RU003489V1

Ontologies

Keywords
Biological process	Protein biosynthesis RuleBase RU003489V1
Ligand	ATP-binding RuleBase RU003489V1 Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase RuleBase RU003489V1 Ligase
Gene Ontology (GO)
Biological process	valyl-tRNA aminoacylation Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	ATP binding Inferred from electronic annotation. Source: InterPro valine-tRNA ligase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5SQ95-1 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 3E37047AE0E46F5F	FASTA	993	110,994
	10 20 30 40 50 60 MPHLPLASFR PPFWGLRHSR GLPRFHSVST QSEPHGSPIS RRNREAKQKR LREKQATLEA 70 80 90 100 110 120 EIAGESKSPA ESIKAWRPKE LVLYEIPTKP GEKKDVSGPL PPAYSPRYVE AAWYPWWVRE 130 140 150 160 170 180 GFFKPEYQAR LPQATGETFS MCIPPPNVTG SLHIGHALTV AIQDALVRWH RMRGDQVLWV 190 200 210 220 230 240 PGSDHAGIAT QAVVEKQLWK ERGVRRHELS REAFLREVWQ WKEAKGGEIC EQLRALGASL 250 260 270 280 290 300 DWDRECFTMD VGSSVAVTEA FVRLYKAGLL YRNHQLVNWS CALRSAISDI EVENRPLPGH 310 320 330 340 350 360 TQPLPLITDY AVQPHVGTGA VKVTPAHSPA DAEMGARHGL SPLNVIAEDG TMTSLCGDWL 370 380 390 400 410 420 QGLHRFVARE KIMSVLSERG LFRGLQNHPM VLPICSRSGD VIEYLLKNQW FVRCQEMGAR 430 440 450 460 470 480 AAKAVESGAL ELSPSFHQKN WQHWFSHIGD WCVSRQLWWG HQIPAYLVVE DHAQGEEDCW 490 500 510 520 530 540 VVGRSEAEAR EVAAELTGRP GAELTLERDP DVLDTWFSSA LFPFSALGWP QETPDLARFY 550 560 570 580 590 600 PLSLLETGSD LLLFWVGRMV MLGTQLTGQL PFSKVLLHPM VRDRQGRKMS KSLGNVLDPR 610 620 630 640 650 660 DIISGVEMQL LQEKLRSGNL DPAELAIVAA AQKKDFPHGI PECGTDALRF TLCSHGVQAG 670 680 690 700 710 720 DLHLSVSEVQ SCRHFCNKIW NALRFILNAL GEKFVPQPAE ELSPSSPMDA WILSRLALAA 730 740 750 760 770 780 QECERGFLTR ELSLVTHALH HFWLHNLCDV YLEAVKPVLW HSPRPLGPPQ VLFSCADLGL 790 800 810 820 830 840 RLLAPLMPFL AEELWQRLPP RPGCPPAPSI SVAPYPSACS LEHWRQPELE RRFSRVQEVV 850 860 870 880 890 900 QVLRALRATY QLTKARPRVL LQSSEPGDQG LFEAFLEPLG TLGYCGAVGL LPPGTAAPSG 910 920 930 940 950 960 WAQAPLSDTA QVYMELQGLV DPQIQLPLLA ARRYKLQKQL DSLTARTPSE GEAGTQRQQK 970 980 990 LSSLQLELSK LDKAASHLRQ LMDEPPAPGS PEL

References

[1]	Almeida J. Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL773541 Genomic DNA. Translation: CAI18454.1.
UniGene	Hs.597526
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSG00000137411. Homo sapiens. [Contig view]
Organism-specific databases
HGNC	HGNC:21642. VARSL.
GenAtlas	Search...
GeneCards	Search...
Phylogenomic databases
HOVERGEN	Q5SQ95.
Gene expression databases
ArrayExpress	Q5SQ95.
Family and domain databases
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR002300. aa-tRNA-synth_Ia. IPR014729. Rossmann-like_a/b/a_fold. IPR013155. V/L/I-tRNA-synth_anticodon-bd. IPR002303. Val-tRNA_synth_Ia. [Graphical view]
Gene3D	G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11946:SF5. tRNA-synt_val. 1 hit.
Pfam	PF08264. Anticodon_1. 1 hit. PF00133. tRNA-synt_1. 1 hit. [Graphical view]
PRINTS	PR00986. TRNASYNTHVAL.
TIGRFAMs	TIGR00422. valS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]

Entry information

Entry name

Q5SQ95_HUMAN

Accession

Primary (citable) accession number: Q5SQ95

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	July 22, 2008
This is version 43 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)