Reviewed,
UniProtKB/Swiss-Prot Q5SPD7 (P5CR3_DANRE)
Last modified
November 25, 2008.
Version 30.
History...
Clusters with 100%,
90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: Pyrroline-5-carboxylate reductase 3 Short name=P5C reductase 3 Short name=P5CR 3 EC=1.5.1.2 Alternative name(s): Pyrroline-5-carboxylate reductase-like protein | ||||
| Gene names |
| ||||
| Organism | Danio rerio (Zebrafish) (Brachydanio rerio) | ||||
| Taxonomic identifier | 7955 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Cyprinidae › Danio |
Protein attributes
| Sequence length | 288 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at transcript level. |
General annotation (Comments)
| Catalytic activity | L-proline + NAD(P)(+) = 1-pyrroline-5-carboxylate + NAD(P)H. |
| Pathway | |
| Subunit structure | Homodecamer; composed of 5 homodimers By similarity. |
| Sequence similarities | Belongs to the pyrroline-5-carboxylate reductase family. |
Ontologies
Keywords | |
|---|---|
| Biological process | Amino-acid biosynthesis Proline biosynthesis |
| Ligand | NADP |
| Molecular function | Oxidoreductase |
Gene Ontology (GO) | |
| Biological process | oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW proline biosynthetic processInferred from electronic annotation. Source: InterPro |
| Molecular function | binding Inferred from electronic annotation. Source: InterPro pyrroline-5-carboxylate reductase activityInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 288 | 288 | Pyrroline-5-carboxylate reductase 3 | PRO_0000324565 | |||
Sequences
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References
| [1] | The Danio rerio sequencing project at the Sanger Institute Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Tuebingen. |
| [2] | NIH - Zebrafish Gene Collection (ZGC) project Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 9-288. |
Cross-references
Sequence databases | |
|---|---|
| AL929003 Genomic DNA. Translation: CAI21008.1. BC124544 mRNA. Translation: AAI24545.1. | |
| RefSeq | NP_001038403.1. |
| UniGene | Dr.81533 |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| Ensembl | ENSDARG00000015236. Danio rerio. [Contig view] |
| GeneID | 560682. |
| KEGG | dre:560682. |
Organism-specific databases | |
| ZFIN | ZDB-GENE-041014-244. pycrl. |
Phylogenomic databases | |
| HOGENOM | Q5SPD7. |
| HOVERGEN | Q5SPD7. |
Gene expression databases | |
| ArrayExpress | Q5SPD7. |
Family and domain databases | |
| InterPro | IPR016040. NAD(P)-bd. IPR004455. NADP_OxRdtase_F420. IPR000304. P5CR. [Graphical view] |
| Gene3D | G3DSA:3.40.50.720. NAD(P)-bd. 1 hit. |
| PANTHER | PTHR11645. P5CR. 1 hit. |
| Pfam | PF03807. F420_oxidored. 1 hit. [Graphical view] |
| PIRSF | PIRSF000193. Pyrrol-5-carb_rd. 1 hit. |
| TIGRFAMs | TIGR00112. proC. 1 hit. |
| PROSITE | PS00521. P5CR. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | P5CR3_DANRE | ||||||||
| Accession | Primary (citable) accession number: Q5SPD7 Secondary accession number(s): Q05AI4 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | Zebrafish annotation project | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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