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Q5SNZ0

- GRDN_MOUSE

UniProt

Q5SNZ0 - GRDN_MOUSE

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Protein
Girdin
Gene
Ccdc88a, Grdn, Kiaa1212
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

Essential for the integrity of the actin cytoskeleton and for cell migration. Required for formation of actin stress fibers and lamellipodia. May be involved in membrane sorting in the early endosome By similarity. Plays a role as a key modulator of the AKT-mTOR signaling pathway controlling the tempo of the process of newborn neurons integration during adult neurogenesis, including correct neuron positioning, dendritic development and synapse formation. Enhances phosphoinositide 3-kinase (PI3K)-dependent phosphorylation and kinase activity of AKT1/PKB, but does not possess kinase activity itself. Phosphorylation of AKT1/PKB thereby induces the phosphorylation of downstream effectors GSK3 and FOXO1/FKHR, and regulates DNA replication and cell proliferation.2 Publications

GO - Molecular functioni

  1. actin binding Source: UniProtKB
  2. microtubule binding Source: UniProtKB
  3. phosphatidylinositol binding Source: UniProtKB
  4. protein binding Source: UniProtKB
  5. protein homodimerization activity Source: UniProtKB
  6. protein kinase B binding Source: UniProtKB

GO - Biological processi

  1. DNA replication Source: UniProtKB-KW
  2. TOR signaling Source: UniProtKB
  3. activation of protein kinase B activity Source: UniProtKB
  4. cell migration Source: UniProtKB
  5. lamellipodium assembly Source: UniProtKB
  6. membrane organization Source: UniProtKB
  7. regulation of DNA replication Source: UniProtKB
  8. regulation of actin cytoskeleton organization Source: UniProtKB
  9. regulation of cell proliferation Source: UniProtKB
  10. regulation of neuron projection development Source: UniProtKB
  11. regulation of protein phosphorylation Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

DNA replication, Neurogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Girdin
Alternative name(s):
Akt phosphorylation enhancer
Short name:
APE
Coiled-coil domain-containing protein 88A
G alpha-interacting vesicle-associated protein
Short name:
GIV
Girders of actin filament
Hook-related protein 1
Short name:
HkRP1
Gene namesi
Name:Ccdc88a
Synonyms:Grdn, Kiaa1212
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:1925177. Ccdc88a.

Subcellular locationi

Membrane. Cell membrane. Cytoplasmcytosol. Cytoplasmic vesicle. Cell projectionlamellipodium By similarity
Note: Localizes to the cell membrane through interaction with phosphoinositides By similarity.

GO - Cellular componenti

  1. Golgi apparatus Source: UniProtKB
  2. cytoplasmic membrane-bounded vesicle Source: UniProtKB-SubCell
  3. cytoplasmic vesicle Source: UniProtKB
  4. cytosol Source: UniProtKB
  5. endoplasmic reticulum Source: UniProtKB
  6. lamellipodium Source: UniProtKB
  7. membrane Source: UniProtKB
  8. plasma membrane Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Cell projection, Cytoplasm, Cytoplasmic vesicle, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 18731873Girdin
PRO_0000287430Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1387 – 13871Phosphoserine By similarityBy similarity
Modified residuei1417 – 14171Phosphoserine; by PKB/AKT1 By similarityBy similarity
Modified residuei1677 – 16771Phosphoserine1 Publication
Modified residuei1839 – 18391Phosphoserine By similarity

Post-translational modificationi

Phosphorylation is induced by epidermal growth factor (EGF) in a phosphoinositide 3-kinase (PI3K)-dependent manner. Phosphorylation by AKT1/PKB is necessary for the delocalization from the cell membrane and for cell migration By similarity.By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiQ5SNZ0.
PaxDbiQ5SNZ0.
PRIDEiQ5SNZ0.

PTM databases

PhosphoSiteiQ5SNZ0.

Expressioni

Tissue specificityi

Expressed in the dentate gyrus, pyramidal cell layer of hippocampal regions CA1 and CA3 at postnatal 15. Expressed highly in neurons. Weakly in neuron progenitors (at protein level). Expressed in the dentate granule cell layer of the hippocampus. Expressed highly in the adult testis, moderately in the brain and at a low level in the spleen, lungs and fat.3 Publications

Developmental stagei

Temporally and spatially restricted during embryogenesis. At E10.5, expressed in the branchial arches, nasal processes, limbs, somites and dorsal root ganglia. At E11.5, expression persists at these sites in addition to the eye and fore-, mid- and hindbrain. By E12.5, expressed in the interdigital mesenchyme of the limbs. At E13.5, expression in the limbs flanks the digits and also appears in a subset of tendons in the hind- and forelimbs.1 Publication

Gene expression databases

BgeeiQ5SNZ0.
CleanExiMM_CCDC88A.
GenevestigatoriQ5SNZ0.

Interactioni

Subunit structurei

Homodimer. The non-phosphorylated form interacts with phosphatidylinositol 4-phosphate [Pi4P] and weakly with phosphatidylinositol 3-phosphate [Pi3P] By similarity. Interacts with microtubules. Interacts AKT1/PKB (via C-terminus). Interacts (via C-terminus) with DISC1; the interaction is direct. Interacts with AKT proteins; the interaction is inhibited in presence of DISC1.By similarity3 Publications

Protein-protein interaction databases

BioGridi224370. 2 interactions.
IntActiQ5SNZ0. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ5SNZ0.
SMRiQ5SNZ0. Positions 14-163.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni1390 – 140819Phosphoinositide-binding By similarityBy similarity
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili196 – 425230 Reviewed prediction
Add
BLAST
Coiled coili458 – 1232775 Reviewed prediction
Add
BLAST
Coiled coili1268 – 1385118 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Belongs to the CCDC88 family.

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG12793.
GeneTreeiENSGT00690000101702.
HOVERGENiHBG057867.
OMAiCIRLKEL.
OrthoDBiEOG7N0C3V.
PhylomeDBiQ5SNZ0.
TreeFamiTF320231.

Family and domain databases

InterProiIPR027717. Girdin.
IPR008636. Hook-related_fam.
[Graphical view]
PANTHERiPTHR18947. PTHR18947. 1 hit.
PTHR18947:SF30. PTHR18947:SF30. 1 hit.
PfamiPF05622. HOOK. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 11 Publication (identifier: Q5SNZ0-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MENEIFTPLL EQFMTSPLVT WVKTFGPLAA GNGTNLDEYV ALVDGVFLNQ     50
VMLQINPKSE SQRVNKKVNN DASLRIHNLS ILVKQIKFYY QETLQQLIMM 100
PLPDILIIGK NPFSEQGTEE VKKLLLLLLG CAVQCQKKEE FIEKIQGLDF 150
DTKAAVAAHI QEVTHNQENV FDLQWMEVTD MSQEDIEPLL KNMVSHLRRL 200
IDERDEHSET IVELSEERDG VHFLPHASSS AQSPCGSPGM KRTESRQHLS 250
VELADAKAKI RRLRQELEEK TEQLLDCKQE LEQIEVELKR LQQENMNLLS 300
DARSARMYRD ELDALREKAV RVDKLESELS RYKERLHDIE FYKARVEELK 350
EDNQVLLETK TMLEDQLEGT RARSDKLHEL EKENLQLKAK LHDMEMERDM 400
DRKKIEELME ENMTLEMAQK QSMDESLHLG WELEQISRTS ELAEAPQKSL 450
GHEVNELTSS KLLKLEMENQ SLTKTVEELR STADSAAGST SKILKVEKEN 500
QRLNKKVEIL ENEIIQEKQS LQNCQNLSKD LMKEKAQLEK TIETLRENSE 550
RQIKILEQEN EHLNQTVSSL RQRSQISAEA RVKDIEKENK ILHESIKETC 600
GKLSKIEFEK RQMKKELELY KEKGERAEEL ENELNHLGKE NELLQKKITN 650
LKITCEKLET LEQENSELER ENRKFKKTLD SFKNLTFQLE SLEKENSQLD 700
EENLELRRSV ESLKCASMRM AQLQLENKEL ESEKEQLRKG LELMRASFKK 750
TERLEVSYQG LDTENQRLQK ALENSNKKIQ QLESELQDLE MENQTLQKSL 800
EELKISSKRL EQLEKENKSL EQETSQLEKD KKQLEKENKR LRQQAEIKDT 850
TLEENNVKIG NLEKENKTLF KEINVYKESC VRLKELEKEN KELVKRATID 900
IKTLVTLRED LVSEKLKTQQ MNNDLEKLTH ELEKIGLNKE RLLHDEQSTD 950
DSRYKLLESK LESTLKKSLE IKEEKIAALE ARLEESTNYN QQLRHELKTV 1000
KKNYEALKQR QDEERMVQSS IPVSGEDDKW GRESQEATRE LLKVKDRLIE 1050
VERNNATLQA EKQALKTQLK QLETQNNNLQ AQILALQRQT VSLQEQNTTL 1100
QTQNAKLQVE NSTLNSQSTS LMNQNAQLLI QQSSLENENE SIMKEREDLK 1150
SLYDALIKDH EKLELLHERQ ASEYESLISK HGTLKSAHKN LEVEHKDLED 1200
RYNQLLKQKG QLEDLEKMIK TEQEKMLLES KNHEVVASEY KKLCGENDRL 1250
NYTYSQLLKE TEILQMDHKN LKSVLNNSKL EQTRLEAEFS KLKEQYQQLD 1300
ITSTKLNNQC ELLSQLKGNL EEENRHLLDQ IQTLMLQNRT LLEQNMESKD 1350
LFHVEQRQYI DKLNELRRQK EKLEEKIMDQ YKFYDPSPPR RRGNWITLKM 1400
RKLIKSKKDI NRERQKSLTL TPTRSDSSEG FLQLPHQDSQ DSSSVGSNSL 1450
EDGQTLGTKK SSMVALKRLP FLRNRPKDKD KMKACYRRSM SMNDLVQSMV 1500
LAGGQWTGST ENLEVPDDIS TGKRRKELGA MAFSTTAINF STVNSSAAFR 1550
SKQLVNNKDT TSFEDISPQG ISDDSSTGSR VHASRPASLD SGRTSTSNSN 1600
NNASLHEVKA GAVNIQSRPQ SHSSGDFSLL HDHETWSSSG SSPIQYLKRQ 1650
TRSSPMLQHK ISETIESRAH HKMKAGSPGS EVVTLQQFLE ESNKLTSIQL 1700
KSSSQENLLD EVMKSLSVSS DFLGKDKPVS CTLARSVSGK TPGDFYDRRT 1750
TKPEFLRTGP QKTEDAYTIS SAGKPTPSTQ GKIKLVKETS VSRQSKDSNP 1800
YATLPRASSV ISTAEGTTRR TSIHDFLSKD SRLPVSVDSS PPTAGSSSTT 1850
ASNVNKVQES RNSKSRSREQ QSS 1873

Note: No experimental confirmation available.

Length:1,873
Mass (Da):215,918
Last modified:May 15, 2007 - v2
Checksum:i0E827E3D9336161F
GO
Isoform 21 Publication (identifier: Q5SNZ0-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1463-1491: MVALKRLPFLRNRPKDKDKMKACYRRSMS → T

Show »
Length:1,845
Mass (Da):212,497
Checksum:i87AEDC047EA4A72A
GO
Isoform 31 Publication (identifier: Q5SNZ0-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1000-1054: Missing.
     1463-1491: MVALKRLPFLRNRPKDKDKMKACYRRSMS → T

Note: No experimental confirmation available.

Show »
Length:1,790
Mass (Da):205,970
Checksum:iCD0309B2B554AB94
GO

Sequence cautioni

The sequence AAH37020.1 differs from that shown. Reason: Erroneous initiation.
The sequence CAI24877.1 differs from that shown. Reason: Erroneous gene model prediction.

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1000 – 105455Missing in isoform 3. 1 Publication
VSP_052410Add
BLAST
Alternative sequencei1463 – 149129MVALK…RRSMS → T in isoform 2 and isoform 3. 2 Publications
VSP_052411Add
BLAST

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti952 – 9521Missing in CAI35999. 1 Publication
Sequence conflicti1086 – 10894LQRQ → PRVR in AAH37020. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB087827 mRNA. Translation: BAD98263.1.
AL935054 Genomic DNA. Translation: CAI24877.1. Sequence problems.
AL935054, BX284634 Genomic DNA. Translation: CAI24878.1.
BX284634 Genomic DNA. Translation: CAI35999.1.
BX284634 Genomic DNA. Translation: CAI36000.1.
BX284634, AL935054 Genomic DNA. Translation: CAI36001.1.
BX284634 Genomic DNA. Translation: CAI36002.1.
BC037020 mRNA. Translation: AAH37020.1. Different initiation.
AK082771 mRNA. Translation: BAC38612.1.
CCDSiCCDS24494.1. [Q5SNZ0-2]
RefSeqiNP_789811.2. NM_176841.4. [Q5SNZ0-2]
XP_006514518.1. XM_006514455.1. [Q5SNZ0-1]
UniGeneiMm.338284.
Mm.441367.

Genome annotation databases

EnsembliENSMUST00000040182; ENSMUSP00000048978; ENSMUSG00000032740. [Q5SNZ0-2]
GeneIDi108686.
KEGGimmu:108686.
UCSCiuc007igw.1. mouse. [Q5SNZ0-2]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AB087827 mRNA. Translation: BAD98263.1 .
AL935054 Genomic DNA. Translation: CAI24877.1 . Sequence problems.
AL935054 , BX284634 Genomic DNA. Translation: CAI24878.1 .
BX284634 Genomic DNA. Translation: CAI35999.1 .
BX284634 Genomic DNA. Translation: CAI36000.1 .
BX284634 , AL935054 Genomic DNA. Translation: CAI36001.1 .
BX284634 Genomic DNA. Translation: CAI36002.1 .
BC037020 mRNA. Translation: AAH37020.1 . Different initiation.
AK082771 mRNA. Translation: BAC38612.1 .
CCDSi CCDS24494.1. [Q5SNZ0-2 ]
RefSeqi NP_789811.2. NM_176841.4. [Q5SNZ0-2 ]
XP_006514518.1. XM_006514455.1. [Q5SNZ0-1 ]
UniGenei Mm.338284.
Mm.441367.

3D structure databases

ProteinModelPortali Q5SNZ0.
SMRi Q5SNZ0. Positions 14-163.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 224370. 2 interactions.
IntActi Q5SNZ0. 1 interaction.

PTM databases

PhosphoSitei Q5SNZ0.

Proteomic databases

MaxQBi Q5SNZ0.
PaxDbi Q5SNZ0.
PRIDEi Q5SNZ0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000040182 ; ENSMUSP00000048978 ; ENSMUSG00000032740 . [Q5SNZ0-2 ]
GeneIDi 108686.
KEGGi mmu:108686.
UCSCi uc007igw.1. mouse. [Q5SNZ0-2 ]

Organism-specific databases

CTDi 55704.
MGIi MGI:1925177. Ccdc88a.
Rougei Search...

Phylogenomic databases

eggNOGi NOG12793.
GeneTreei ENSGT00690000101702.
HOVERGENi HBG057867.
OMAi CIRLKEL.
OrthoDBi EOG7N0C3V.
PhylomeDBi Q5SNZ0.
TreeFami TF320231.

Miscellaneous databases

NextBioi 361223.
PROi Q5SNZ0.
SOURCEi Search...

Gene expression databases

Bgeei Q5SNZ0.
CleanExi MM_CCDC88A.
Genevestigatori Q5SNZ0.

Family and domain databases

InterProi IPR027717. Girdin.
IPR008636. Hook-related_fam.
[Graphical view ]
PANTHERi PTHR18947. PTHR18947. 1 hit.
PTHR18947:SF30. PTHR18947:SF30. 1 hit.
Pfami PF05622. HOOK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), FUNCTION, INTERACTION WITH AKT1, TISSUE SPECIFICITY.
    Tissue: Embryo.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1086-1873 (ISOFORMS 2/3).
    Strain: C57BL/6.
    Tissue: Retina.
  4. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1623-1873.
    Strain: C57BL/6J.
    Tissue: Embryonic stem cell.
  5. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1677, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic brain.
  6. "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
    Rush J., Moritz A., Lee K.A., Guo A., Goss V.L., Spek E.J., Zhang H., Zha X.-M., Polakiewicz R.D., Comb M.J.
    Nat. Biotechnol. 23:94-101(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  7. "A novel hook-related protein family and the characterization of hook-related protein 1."
    Simpson F., Martin S., Evans T.M., Kerr M., James D.E., Parton R.G., Teasdale R.D., Wicking C.
    Traffic 6:442-458(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUBUNIT, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.
  8. "Girdin, a novel actin-binding protein, and its family of proteins possess versatile functions in the Akt and Wnt signaling pathways."
    Enomoto A., Ping J., Takahashi M.
    Ann. N. Y. Acad. Sci. 1086:169-184(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: REVIEW.
  9. "DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212."
    Kim J.Y., Duan X., Liu C.Y., Jang M.H., Guo J.U., Pow-anpongkul N., Kang E., Song H., Ming G.L.
    Neuron 63:761-773(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, INTERACTION WITH DISC1 AND AKT PROTEINS, TISSUE SPECIFICITY.

Entry informationi

Entry nameiGRDN_MOUSE
AccessioniPrimary (citable) accession number: Q5SNZ0
Secondary accession number(s): Q5M6X2
, Q5M6X4, Q5M6X5, Q5SNZ1, Q8C486, Q8CFU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: July 9, 2014
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi