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Q5SMC5 (GLGA_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glycogen synthase

EC=2.4.1.21
Alternative name(s):
Starch [bacterial glycogen] synthase
Gene names
Name:glgA
Ordered Locus Names:TTHA0018
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length437 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Synthesizes alpha-1,4-glucan chains using ADP-glucose By similarity. HAMAP-Rule MF_00484

Catalytic activity

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1). HAMAP-Rule MF_00484

Pathway

Glycan biosynthesis; glycogen biosynthesis. HAMAP-Rule MF_00484

Sequence similarities

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.

Sequence caution

The sequence BAD69841.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
   Biological processGlycogen biosynthesis
   Molecular functionGlycosyltransferase
Transferase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processglycogen biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Molecular_functionstarch synthase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 437437Glycogen synthase HAMAP-Rule MF_00484
PRO_0000230268

Sites

Binding site151ADP-glucose By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5SMC5 [UniParc].

Last modified April 4, 2006. Version 2.
Checksum: 255F032F2EE26452

FASTA43748,259
        10         20         30         40         50         60 
MRVLHVAPEA YPLAKVGGLA DVVGALPKAL RPLGVEAHVL LPWHGGLEAR RVGEVAFAFF 

        70         80         90        100        110        120 
GREERAPLGE RVEGGVRFLL LGVEGFGRER VYGYPDDAER YLRFALAAKE VARGYDLVHA 

       130        140        150        160        170        180 
HDWTAALLAL YAPTVYTIHN LAHQGLVDPG LFFSWTGLPW SLFHMEALEF YGRVNLMKGG 

       190        200        210        220        230        240 
IVFARRVTTV SPSYAEEIQT PEFGMGLDGV LRRHAGKLRG ILNGLDTEVF DPGKDPYLPA 

       250        260        270        280        290        300 
PYTREDPSGK ARAKEAFRER TGLRPPVLAY VGRLDYQKGL DLVLKALPRL LEMGFRLYVQ 

       310        320        330        340        350        360 
GVGDGGLQEA FLRAEEENPE GVRFLPAYDE AMARLAYAGA EAVLVPSRFE PCGLVQMIAS 

       370        380        390        400        410        420 
RYGTPPVARA VGGLKDTVED GRGGVLFETY HPEGLLYGVL RLFRLGAEEM GLRAMEKDFS 

       430 
WEGPARAYRE VYREALG 

« Hide

References

[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008226 Genomic DNA. Translation: BAD69841.1. Different initiation.
RefSeqYP_143284.1. NC_006461.1.

3D structure databases

ProteinModelPortalQ5SMC5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING300852.TTHA0018.

Protein family/group databases

CAZyGT5. Glycosyltransferase Family 5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD69841; BAD69841; BAD69841.
GeneID3169395.
KEGGttj:TTHA0018.
PATRIC23954971. VBITheThe93045_0019.

Phylogenomic databases

eggNOGCOG0297.
HOGENOMHOG000294941.
KOK00703.
OMAICVISRI.
OrthoDBEOG6JTC6Z.

Enzyme and pathway databases

BioCycTTHE300852:GH8R-21-MONOMER.
UniPathwayUPA00164.

Family and domain databases

HAMAPMF_00484. Glycogen_synth.
InterProIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsTIGR02095. glgA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameGLGA_THET8
AccessionPrimary (citable) accession number: Q5SMC5
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: May 14, 2014
This is version 62 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways