Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q5SM81 (Q5SM81_THET8) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Alanine racemase HAMAP MF_01201
EC=5.1.1.1 HAMAP MF_01201
Gene names
Name:alr HAMAP MF_01201
Ordered Locus Names:TTHA0062
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length360 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Provides the D-alanine required for cell wall biosynthesis By similarity. HAMAP MF_01201

Catalytic activity

L-alanine = D-alanine. HAMAP MF_01201

Cofactor

Pyridoxal phosphate By similarity. HAMAP MF_01201 SAAS SAAS009006

Pathway

Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1. HAMAP MF_01201

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_01201

Sequence similarities

Belongs to the alanine racemase family. HAMAP MF_01201 RuleBase RU004188

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Active site431Proton acceptor; specific for D-alanine By similarity HAMAP MF_01201
Active site2561Proton acceptor; specific for L-alanine By similarity HAMAP MF_01201

Amino acid modifications

Modified residue431N6-(pyridoxal phosphate)lysine By similarity HAMAP MF_01201

Sequences

Sequence LengthMass (Da)Tools
Q5SM81 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: 3CF549D6B1FE7D08

FASTA36038,652
        10         20         30         40         50         60 
MRPGGYPKGV QARAWVEVDL AALWANYRLL AGRAGGEVIP VLKADAYGHG ALPLARFLEG 

        70         80         90        100        110        120 
KGVGRFAVAT LEEGRRLREG GIKGEVLLLG SLHPLEAEEA LRLGLVPTLS NLEAAEALSQ 

       130        140        150        160        170        180 
RARALGLVPR AHLKVDTGMN RVGFPSEEAV SALRAVEALG VRVEGVYTHL ATAGEDAAFV 

       190        200        210        220        230        240 
ETQRRRFQEV RRALGEGYFY HLENSLGLLR HGATAGVRVG LALYGLVPGF GLRPILRILA 

       250        260        270        280        290        300 
RPTLVKRLKA GDRVGYGGVY VARGGEWLAT LPVGYADGLP WGAVRFVKGP DGRLLEVAGR 

       310        320        330        340        350        360 
ISMDQTTVLL PGPVGLEAVF EVLSADFGPT GLLAWAEARG TLPYEVAVHL SRRLPRRYLE

« Hide

References

[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008226 Genomic DNA. Translation: BAD69885.1.
RefSeqYP_143328.1. NC_006461.1.

3D structure databases

ProteinModelPortalQ5SM81.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5SM81.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3168821.
GenomeReviewsGene locus TTHA0062 in contig AP008226_GR.
KEGGttj:TTHA0062.
NMPDRfig|300852.3.peg.93.
PATRIC23955053. VBITheThe93045_0060.

Phylogenomic databases

eggNOGCOG0787.
HOGENOMHBG712172.
OMAIPELEGC.
PhylomeDBQ5SM81.
ProtClustDBCLSK738977.

Enzyme and pathway databases

BioCycTTHE300852:TTHA0062-MONOMER.

Family and domain databases

HAMAPMF_01201. Ala_racemase.
[Tree]
InterProIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
[Graphical view]
Gene3DG3DSA:2.40.37.10. Ala_racemase/Decarboxylase_C. 1 hit.
KOK01775.
PfamPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSPR00992. ALARACEMASE.
SMARTSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMSSF50621. Racem_decarbox_C. 1 hit.
TIGRFAMsTIGR00492. Alr. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ5SM81_THET8
AccessionPrimary (citable) accession number: Q5SM81
Entry history
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info