Q5SLQ1 (RL9_THET8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
50S ribosomal protein L9

Gene names

Name:	rplI
Ordered Locus Names:	TTHA0242

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	148 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Binds to the 23S rRNA. Extends more that 50 Angstroms beyond the surface of the 70S ribosome. HAMAP MF_00503
Subunit structure	Part of the 50S ribosomal subunit.
Sequence similarities	Belongs to the ribosomal protein L9P family.
Mass spectrometry	Molecular mass is 16397 Da from positions 1 - 148. Determined by MALDI. Ref.4

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological process	translation Inferred from electronic annotation. Source: InterPro
Cellular component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	rRNA binding Inferred from electronic annotation. Source: UniProtKB-KW structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 148

148

50S ribosomal protein L9 HAMAP MF_00503

PRO_0000176696

Secondary structure

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148

Helix Strand Turn

Details...

Beta strand

2 – 7

6

Beta strand

9 – 12

4

Beta strand

18 – 20

3

Helix

23 – 30

8

Beta strand

31 – 38

8

Helix

40 – 74

35

Beta strand

75 – 81

7

Beta strand

83 – 87

5

Helix

94 – 105

12

Beta strand

111 – 114

4

Beta strand

124 – 133

10

Beta strand

136 – 146

11

Sequences

	Sequence		Length	Mass (Da)
	Q5SLQ1 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: B807DB9453506A2F	FASTA	148	16,397
	10 20 30 40 50 60 MKVILLEPLE NLGDVGQVVD VKPGYARNYL LPRGLAVLAT ESNLKALEAR IRAQAKRLAE 70 80 90 100 110 120 RKAEAERLKE ILENLTLTIP VRAGETKIYG SVTAKDIAEA LSRQHGVTID PKRLALEKPI 130 140 KELGEYVLTY KPHPEVPIQL KVSVVAQE

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.
[2]	"The isolation and complete amino acid sequence of the ribosomal protein L36 from Thermus thermophilus and its zinc-binding motif." Boysen R.I., Lorenz S., Kim J.S., Schroeder W.F.K.J., Erdmann V.A. Endocyt. Cell Res. 11:41-58(1995) Cited for: PROTEIN SEQUENCE OF 1-31.
[3]	"Identification of the 50S ribosomal proteins from the eubacterium Thermus thermophilus." Katsani K.R., Tsiboli P., Anagnostopoulos K., Urlaub H., Choli-Papadopoulou T. Biol. Chem. 381:1079-1087(2000) [PubMed: 11154066] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-15.
[4]	"Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry." Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A. Proteomics 5:4818-4831(2005) [PubMed: 16287167] [Abstract] Cited for: MASS SPECTROMETRY.
[5]	"The path of messenger RNA through the ribosome." Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F. Cell 106:233-241(2001) [PubMed: 11511350] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
[6]	"Crystal structure of the ribosome at 5.5 A resolution." Yusupov M.M., Yusupova G.Z., Baucom A., Lieberman K., Earnest T.N., Cate J.H.D., Noller H.F. Science 292:883-896(2001) [PubMed: 11283358] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.
+	Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AP008226 Genomic DNA. Translation: BAD70065.1.

RefSeq

YP_143508.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1GIY	X-ray	5.50	K	34-106	[»]
1YL3	X-ray	5.50	K	34-106	[»]
2HGJ	X-ray	5.00	K	1-148	[»]
2HGQ	X-ray	5.50	K	1-148	[»]
2HGU	X-ray	4.51	K	1-148	[»]
2J01	X-ray	2.80	I	1-148	[»]
2J03	X-ray	2.80	I	1-148	[»]
2V47	X-ray	3.80	I	1-148	[»]
2V49	X-ray	3.80	I	1-148	[»]
2WDI	X-ray	3.30	I	1-148	[»]
2WDJ	X-ray	3.30	I	1-148	[»]
2WDL	X-ray	3.50	I	1-148	[»]
2WDN	X-ray	3.50	I	1-148	[»]
2WH2	X-ray	3.45	I	1-148	[»]
2WH4	X-ray	3.45	I	1-148	[»]
2X9S	X-ray	3.10	I	1-148	[»]
2X9U	X-ray	3.10	I	1-148	[»]
2XG0	X-ray	3.20	I	1-148	[»]
2XG2	X-ray	3.20	I	1-148	[»]
3F1F	X-ray	3.00	I	1-148	[»]
3F1H	X-ray	3.00	I	1-148	[»]
3FIN	electron microscopy	6.40	I	1-145	[»]
3HUX	X-ray	3.10	I	1-148	[»]
3HUZ	X-ray	3.10	I	1-148	[»]
3I8F	X-ray	3.10	K	1-148	[»]
3I8I	X-ray	3.10	K	1-148	[»]
3I9C	X-ray	3.50	K	1-148	[»]
3I9E	X-ray	3.50	K	1-148	[»]
3KIR	X-ray	3.30	I	1-148	[»]
3KIT	X-ray	3.30	I	1-148	[»]
3KIW	X-ray	3.60	I	1-148	[»]
3KIY	X-ray	3.60	I	1-148	[»]
3KNI	X-ray	3.00	I	1-148	[»]
3KNK	X-ray	3.00	I	1-148	[»]
3KNM	X-ray	3.45	I	1-148	[»]
3KNO	X-ray	3.45	I	1-148	[»]

ProteinModelPortal

Q5SLQ1.

SMR

Q5SLQ1. Positions 1-145.

ModBase

Search...

Protein-protein interaction databases

STRING

Q5SLQ1.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

3168676.

GenomeReviews

Gene locus TTHA0242 in contig AP008226_GR.

KEGG

ttj:TTHA0242.

NMPDR

fig|300852.3.peg.273.

PATRIC

23955429. VBITheThe93045_0242.

Phylogenomic databases

eggNOG

COG0359.

HOGENOM

HBG586587.

OMA

SGKLFGT.

PhylomeDB

Q5SLQ1.

ProtClustDB

PRK00137.

Enzyme and pathway databases

BioCyc

TTHE300852:TTHA0242-MONOMER.

Family and domain databases

HAMAP

MF_00503. Ribosomal_L9.
[Tree]

InterPro

IPR000244. Ribosomal_L9.
IPR009027. Ribosomal_L9/RNase_H1_N.
IPR020594. Ribosomal_L9_bac/chp.
IPR020069. Ribosomal_L9_C.
IPR020070. Ribosomal_L9_N.
[Graphical view]

Gene3D

G3DSA:3.10.430.100. Ribosomal_L9. 1 hit.
G3DSA:3.40.5.10. Ribosomal_L9. 1 hit.

KO

K02939.

PANTHER

PTHR21368. Ribosomal_L9. 1 hit.

Pfam

PF03948. Ribosomal_L9_C. 1 hit.
PF01281. Ribosomal_L9_N. 1 hit.
[Graphical view]

SUPFAM

SSF55658. L9_N_like. 1 hit.
SSF55653. Ribosomal_L9. 1 hit.

TIGRFAMs

TIGR00158. L9. 1 hit.

PROSITE

PS00651. RIBOSOMAL_L9. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

RL9_THET8

Accession

Primary (citable) accession number: Q5SLQ1

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 29, 2005
Last sequence update:	December 21, 2004
Last modified:	January 25, 2012
This is version 61 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program