30S ribosomal protein S6 - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

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Q5SLP8 (RS6_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 78. History...

Clusters with 100%, 90%, 50% identity |

Documents (3) |

Third-party data

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Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·Documents Customize order

Names and origin

Protein names

Recommended name:
30S ribosomal protein S6

Alternative name(s):
TS9

Gene names

Name:	rpsF
Ordered Locus Names:	TTHA0245

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus ›

Protein attributes

Sequence length	101 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Located on the outer edge of the platform on the body of the 30S subunit. HAMAP-Rule MF_00360
Subunit structure	Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S18. May make transient contacts with protein L2 of the 50S subunit during translation. Ref.4 Ref.5 Ref.6 Ref.7 Ref.8 Ref.9 Ref.11 Ref.12 Ref.14 Ref.15
Sequence similarities	Belongs to the ribosomal protein S6P family.
Mass spectrometry	Molecular mass is 11973 Da from positions 1 - 101. Determined by MALDI. Ref.3

Ontologies

Keywords
Ligand	RNA-binding rRNA-binding
Molecular function	Ribonucleoprotein Ribosomal protein
Technical term	3D-structure Complete proteome Direct protein sequencing Reference proteome
Gene Ontology (GO)
Biological_process	translation Inferred from electronic annotation. Source: HAMAP
Cellular_component	ribosome Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	rRNA binding Inferred from electronic annotation. Source: HAMAP structural constituent of ribosome Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 101

101

30S ribosomal protein S6 HAMAP-Rule MF_00360

PRO_0000176863

Secondary structure

101

Helix Strand Turn

Details...

Sequences

Sequence

Length

Mass (Da)

Tools

Q5SLP8 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: 4FEE8005C74902E5
Show »

FASTA

101

11,973

        10         20         30         40         50         60 
MRRYEVNIVL NPNLDQSQLA LEKEIIQRAL ENYGARVEKV EELGLRRLAY PIAKDPQGYF 

        70         80         90        100 
LWYQVEMPED RVNDLARELR IRDNVRRVMV VKSQEPFLAN A

« Hide

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.
[2]	"Purification and characterization of the 30S ribosomal proteins from the bacterium Thermus thermophilus." Tsiboli P., Herfurth E., Choli T. Eur. J. Biochem. 226:169-177(1994) [PubMed] [Europe PMC] [Abstract] Cited for: PROTEIN SEQUENCE OF 1-16.
[3]	"Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry." Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A. Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract] Cited for: MASS SPECTROMETRY.
[4]	"Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution." Clemons W.M. Jr., May J.L.C., Wimberly B.T., McCutcheon J.P., Capel M.S., Ramakrishnan V. Nature 400:833-840(1999) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE 30S SUBUNIT.
[5]	"Structure of the S15,S6,S18-rRNA complex: assembly of the 30S ribosome central domain." Agalarov S.C., Prasad G.S., Funke P.M., Stout C.D., Williamson J.R. Science 288:107-113(2000) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF A 30S SUBUNIT FRAGMENT.
[6]	"Structure of the 30S ribosomal subunit." Wimberly B.T., Brodersen D.E., Clemons W.M. Jr., Morgan-Warren R.J., Carter A.P., Vonrhein C., Hartsch T., Ramakrishnan V. Nature 407:327-339(2000) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF THE 30S SUBUNIT.
[7]	"Structure of functionally activated small ribosomal subunit at 3.3 A resolution." Schluenzen F., Tocilj A., Zarivach R., Harms J., Gluehmann M., Janell D., Bashan A., Bartels H., Agmon I., Franceschi F., Yonath A. Cell 102:615-623(2000) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 30S SUBUNIT.
[8]	"The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit." Brodersen D.E., Clemons W.M. Jr., Carter A.P., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V. Cell 103:1143-1154(2000) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 30S SUBUNIT.
[9]	"Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics." Carter A.P., Clemons W.M. Jr., Brodersen D.E., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V. Nature 407:340-348(2000) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 30S SUBUNIT.
[10]	"The path of messenger RNA through the ribosome." Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F. Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
[11]	"Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3." Pioletti M., Schluenzen F., Harms J., Zarivach R., Gluehmann M., Avila H., Bashan A., Bartels H., Auerbach T., Jacobi C., Hartsch T., Yonath A., Franceschi F. EMBO J. 20:1829-1839(2001) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF THE 30S SUBUNIT.
[12]	"Crystal structure of an initiation factor bound to the 30S ribosomal subunit." Carter A.P., Clemons W.M. Jr., Brodersen D.E., Morgan-Warren R.J., Hartsch T., Wimberly B.T., Ramakrishnan V. Science 291:498-501(2001) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF THE 30S SUBUNIT.
[13]	"Crystal structure of the ribosome at 5.5 A resolution." Yusupov M.M., Yusupova G.Z., Baucom A., Lieberman K., Earnest T.N., Cate J.H.D., Noller H.F. Science 292:883-896(2001) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.
[14]	"Recognition of cognate transfer RNA by the 30S ribosomal subunit." Ogle J.M., Brodersen D.E., Clemons W.M. Jr., Tarry M.J., Carter A.P., Ramakrishnan V. Science 292:897-902(2001) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.11 ANGSTROMS) OF THE 30S SUBUNIT.
[15]	"Crystal structure of the 30S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16S RNA." Brodersen D.E., Clemons W.M. Jr., Carter A.P., Wimberly B.T., Ramakrishnan V. J. Mol. Biol. 316:725-768(2002) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF THE 30S SUBUNIT.
+	Additional computationally mapped references.

Web resources

T.thermophilus ribosome structure and function

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AP008226 Genomic DNA. Translation: BAD70068.1.

RefSeq

YP_143511.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
1FJG	X-ray	3.00	F	1-101	[»]
1FKA	X-ray	3.30	F	1-101	[»]
1G1X	X-ray	2.60	A/F	1-98	[»]
1GIX	X-ray	5.50	I	1-101	[»]
1HNW	X-ray	3.40	F	1-101	[»]
1HNX	X-ray	3.40	F	1-101	[»]
1HNZ	X-ray	3.30	F	1-101	[»]
1HR0	X-ray	3.20	F	1-101	[»]
1I94	X-ray	3.20	F	1-101	[»]
1I95	X-ray	4.50	F	1-101	[»]
1I96	X-ray	4.20	F	1-101	[»]
1I97	X-ray	4.50	F	1-101	[»]
1IBK	X-ray	3.31	F	1-101	[»]
1IBL	X-ray	3.11	F	1-101	[»]
1IBM	X-ray	3.31	F	1-101	[»]
1J5E	X-ray	3.05	F	1-101	[»]
1JGO	X-ray	5.60	I	1-101	[»]
1JGP	X-ray	7.00	I	1-101	[»]
1JGQ	X-ray	5.00	I	1-101	[»]
1L1U	model	-	F	1-101	[»]
1N32	X-ray	3.00	F	1-101	[»]
1N33	X-ray	3.35	F	1-101	[»]
1N34	X-ray	3.80	F	1-101	[»]
1N36	X-ray	3.65	F	1-101	[»]
1QD7	X-ray	5.50	E	1-97	[»]
1XMO	X-ray	3.25	F	1-101	[»]
1XMQ	X-ray	3.00	F	1-101	[»]
1XNQ	X-ray	3.05	F	1-101	[»]
1XNR	X-ray	3.10	F	1-101	[»]
1YL4	X-ray	5.50	I	1-101	[»]
2B64	X-ray	5.90	F	1-101	[»]
2B9M	X-ray	6.76	F	1-101	[»]
2B9O	X-ray	6.46	F	1-101	[»]
2E5L	X-ray	3.30	F	1-101	[»]
2F4V	X-ray	3.80	F	1-101	[»]
2HGI	X-ray	5.00	I	1-101	[»]
2HGP	X-ray	5.50	I	1-101	[»]
2HGR	X-ray	4.51	I	1-101	[»]
2HHH	X-ray	3.35	F	1-101	[»]
2J00	X-ray	2.80	F	1-101	[»]
2J02	X-ray	2.80	F	1-101	[»]
2KJV	NMR	-	A	1-101	[»]
2KJW	NMR	-	A	3-91	[»]
2OW8	X-ray	3.71	g	-	[»]
2UU9	X-ray	3.10	F	1-101	[»]
2UUA	X-ray	2.90	F	1-101	[»]
2UUB	X-ray	2.90	F	1-101	[»]
2UUC	X-ray	3.10	F	1-101	[»]
2UXB	X-ray	3.10	F	1-101	[»]
2UXC	X-ray	2.90	F	1-101	[»]
2UXD	X-ray	3.20	F	1-101	[»]
2V46	X-ray	3.80	F	1-101	[»]
2V48	X-ray	3.80	F	1-101	[»]
2VQE	X-ray	2.50	F	1-101	[»]
2VQF	X-ray	2.90	F	1-101	[»]
2WDG	X-ray	3.30	F	1-101	[»]
2WDH	X-ray	3.30	F	1-101	[»]
2WDK	X-ray	3.50	F	1-101	[»]
2WDM	X-ray	3.50	F	1-101	[»]
2WH1	X-ray	3.45	F	1-101	[»]
2WH3	X-ray	3.45	F	1-101	[»]
2WRI	X-ray	3.60	F	1-101	[»]
2WRK	X-ray	3.60	F	1-101	[»]
2WRN	X-ray	3.60	F	1-101	[»]
2WRQ	X-ray	3.60	F	1-101	[»]
2X9R	X-ray	3.10	F	1-101	[»]
2X9T	X-ray	3.10	F	1-101	[»]
2XFZ	X-ray	3.20	F	1-101	[»]
2XG1	X-ray	3.20	F	1-101	[»]
2XQD	X-ray	3.10	F	1-101	[»]
2XSY	electron microscopy	7.80	F	1-101	[»]
2XUY	electron microscopy	7.60	F	1-101	[»]
2Y0U	X-ray	3.10	F	1-101	[»]
2Y0W	X-ray	3.10	F	1-101	[»]
2Y0Y	X-ray	3.10	F	1-101	[»]
2Y10	X-ray	3.10	F	1-101	[»]
2Y12	X-ray	3.10	F	1-101	[»]
2Y14	X-ray	3.10	F	1-101	[»]
2Y16	X-ray	3.10	F	1-101	[»]
2Y18	X-ray	3.10	F	1-101	[»]
2ZM6	X-ray	3.30	F	1-101	[»]
3FIC	electron microscopy	6.40	F	1-101	[»]
3HUW	X-ray	3.10	F	1-101	[»]
3HUY	X-ray	3.10	F	1-101	[»]
3I8G	X-ray	3.10	I	1-101	[»]
3I8H	X-ray	3.10	I	1-101	[»]
3I9B	X-ray	3.50	I	1-101	[»]
3I9D	X-ray	3.50	I	1-101	[»]
3KIQ	X-ray	3.30	f	1-101	[»]
3KIS	X-ray	3.30	f	1-101	[»]
3KIU	X-ray	3.60	f	1-101	[»]
3KIX	X-ray	3.60	f	1-101	[»]
3KNH	X-ray	3.00	F	1-101	[»]
3KNJ	X-ray	3.15	F	1-101	[»]
3KNL	X-ray	3.45	F	1-101	[»]
3KNN	X-ray	3.45	F	1-101	[»]
3OGE	X-ray	3.00	F	1-101	[»]
3OGY	X-ray	3.00	F	1-101	[»]
3OHC	X-ray	3.00	F	1-101	[»]
3OHD	X-ray	3.00	F	1-101	[»]
3OHY	X-ray	3.00	F	1-101	[»]
3OI0	X-ray	3.00	F	1-101	[»]
3OI2	X-ray	3.10	F	1-101	[»]
3OI4	X-ray	3.10	F	1-101	[»]
3OTO	X-ray	3.69	F	1-101	[»]
3T1H	X-ray	3.11	F	1-101	[»]
3T1Y	X-ray	2.80	F	1-101	[»]
3TVF	X-ray	3.10	I	1-101	[»]
3TVG	X-ray	3.10	I	1-101	[»]
3UXS	X-ray	3.20	F	1-101	[»]
3UXT	X-ray	3.20	F	1-101	[»]
3UYD	X-ray	3.00	I	1-101	[»]
3UYF	X-ray	3.00	I	1-101	[»]
3UZ3	X-ray	3.30	I	1-101	[»]
3UZ4	X-ray	3.30	I	1-101	[»]
3UZ6	X-ray	3.00	I	1-101	[»]
3UZ7	X-ray	3.00	I	1-101	[»]
3UZG	X-ray	3.30	I	1-101	[»]
3UZI	X-ray	3.30	I	1-101	[»]
3UZL	X-ray	3.30	I	1-101	[»]
3UZM	X-ray	3.30	I	1-101	[»]
3V22	X-ray	3.00	F	1-101	[»]
3V24	X-ray	3.00	F	1-101	[»]
3V26	X-ray	3.10	F	1-101	[»]
3V28	X-ray	3.10	F	1-101	[»]
3V2C	X-ray	2.70	F	1-101	[»]
3V2E	X-ray	2.70	F	1-101	[»]
3ZVO	X-ray	3.80	F	1-101	[»]
3ZZP	X-ray	0.96	A	3-91	[»]
4ABR	X-ray	3.10	F	1-101	[»]
4AQY	X-ray	3.50	F	1-101	[»]
4DH9	X-ray	3.20	F	1-101	[»]
4DHB	X-ray	3.20	F	1-101	[»]
4DR1	X-ray	3.60	F	1-101	[»]
4DR2	X-ray	3.25	F	1-101	[»]
4DR3	X-ray	3.35	F	1-101	[»]
4DR4	X-ray	3.97	F	1-101	[»]
4DR5	X-ray	3.45	F	1-101	[»]
4DR6	X-ray	3.30	F	1-101	[»]
4DR7	X-ray	3.75	F	1-101	[»]
4DUY	X-ray	3.39	F	1-101	[»]
4DUZ	X-ray	3.65	F	1-101	[»]
4DV0	X-ray	3.85	F	1-101	[»]
4DV1	X-ray	3.85	F	1-101	[»]
4DV2	X-ray	3.65	F	1-101	[»]
4DV3	X-ray	3.55	F	1-101	[»]
4DV4	X-ray	3.65	F	1-101	[»]
4DV5	X-ray	3.68	F	1-101	[»]
4DV6	X-ray	3.30	F	1-101	[»]
4DV7	X-ray	3.29	F	1-101	[»]
4G5K	X-ray	3.30	I	1-101	[»]
4G5M	X-ray	3.30	I	1-101	[»]
4G5T	X-ray	3.10	I	1-101	[»]
4G5V	X-ray	3.10	I	1-101	[»]

ProteinModelPortal

Q5SLP8.

SMR

Q5SLP8. Positions 1-101.

ModBase

Search...

Protein-protein interaction databases

STRING

300852.TTHA0245.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

BAD70068; BAD70068; BAD70068.

GeneID

3168355.

KEGG

ttj:TTHA0245.

PATRIC

23955435. VBITheThe93045_0245.

Phylogenomic databases

eggNOG

COG0360.

HOGENOM

HOG000040440.

K02990.

OMA

REGYYLM.

ProtClustDB

PRK00453.

Family and domain databases

Gene3D

3.30.70.60. 1 hit.

HAMAP

MF_00360. Ribosomal_S6.

InterPro

IPR000529. Ribosomal_S6.
IPR020815. Ribosomal_S6_CS.
IPR020814. Ribosomal_S6_plastid/chlpt.
IPR014717. Transl_elong_EF1B/ribosomal_S6.
[Graphical view]

Pfam

PF01250. Ribosomal_S6. 1 hit.
[Graphical view]

SUPFAM

SSF54995. Ribosomal_S6. 1 hit.

TIGRFAMs

TIGR00166. S6. 1 hit.

PROSITE

PS01048. RIBOSOMAL_S6. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q5SLP8.

Entry information

Entry name

RS6_THET8

Accession

Primary (citable) accession number: Q5SLP8

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2005
Last sequence update:	December 21, 2004
Last modified:	May 1, 2013
This is version 78 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program

Relevant documents

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·Documents

Preferred order of sections

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Secondary structure

Sequences

References

Web resources

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Family and domain databases

Other

Entry information

Relevant documents