SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q5SLE7

- Q5SLE7_THET8

UniProt

Q5SLE7 - Q5SLE7_THET8

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Peptidyl-prolyl cis-trans isomerase
Gene
TTHA0346
Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei62 – 621Succinate; via carbonyl oxygenImported
Metal bindingi145 – 1451Nickel; via pros nitrogen
Metal bindingi145 – 1451Zinc; via pros nitrogenImported
Metal bindingi147 – 1471Nickel; via tele nitrogen
Metal bindingi147 – 1471Zinc; via tele nitrogenImported
Metal bindingi149 – 1491Nickel; via tele nitrogen
Metal bindingi149 – 1491Zinc; via tele nitrogenImported

GO - Molecular functioni

  1. metal ion binding Source: UniProtKB-KW
  2. peptidyl-prolyl cis-trans isomerase activity Source: UniProtKB-KW

GO - Biological processi

  1. protein folding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Isomerase, RotamaseUniRule annotation

Keywords - Ligandi

Metal-bindingImported, NickelImported, ZincImported

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-363-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomeraseUniRule annotation (EC:5.2.1.8UniRule annotation)
Gene namesi
Ordered Locus Names:TTHA0346Imported
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
ProteomesiUP000000532: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA0346.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3CGMX-ray2.41A1-149[»]
3CGNX-ray2.70A1-149[»]
3LUOX-ray2.55A1-149[»]
ProteinModelPortaliQ5SLE7.

Miscellaneous databases

EvolutionaryTraceiQ5SLE7.

Family & Domainsi

Sequence similaritiesi

Contains 1 PPIase FKBP-type domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG1047.
HOGENOMiHOG000154889.
KOiK03775.
OMAiHMLAGQT.
OrthoDBiEOG6Q8J79.
PhylomeDBiQ5SLE7.

Family and domain databases

InterProiIPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view]
PANTHERiPTHR10516. PTHR10516. 1 hit.
PfamiPF00254. FKBP_C. 1 hit.
[Graphical view]
PROSITEiPS50059. FKBP_PPIASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SLE7-1 [UniParc]FASTAAdd to Basket

« Hide

MKVGQDKVVT IRYTLQVEGE VLDQGELSYL HGHRNLIPGL EEALEGREEG    50
EAFQAHVPAE KAYGPHDPEG VQVVPLSAFP EDAEVVPGAQ FYAQDMEGNP 100
MPLTVVAVEG EEVTVDFNHP LAGKDLDFQV EVVKVREATP EELLHGHAH 149
Length:149
Mass (Da):16,313
Last modified:December 21, 2004 - v1
Checksum:iFE9ABD7980C37C76
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008226 Genomic DNA. Translation: BAD70169.1.
RefSeqiYP_143612.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70169; BAD70169; BAD70169.
GeneIDi3168679.
KEGGittj:TTHA0346.
PATRICi23955654. VBITheThe93045_0346.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AP008226 Genomic DNA. Translation: BAD70169.1 .
RefSeqi YP_143612.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3CGM X-ray 2.41 A 1-149 [» ]
3CGN X-ray 2.70 A 1-149 [» ]
3LUO X-ray 2.55 A 1-149 [» ]
ProteinModelPortali Q5SLE7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 300852.TTHA0346.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai BAD70169 ; BAD70169 ; BAD70169 .
GeneIDi 3168679.
KEGGi ttj:TTHA0346.
PATRICi 23955654. VBITheThe93045_0346.

Phylogenomic databases

eggNOGi COG1047.
HOGENOMi HOG000154889.
KOi K03775.
OMAi HMLAGQT.
OrthoDBi EOG6Q8J79.
PhylomeDBi Q5SLE7.

Enzyme and pathway databases

BioCyci TTHE300852:GH8R-363-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q5SLE7.

Family and domain databases

InterProi IPR023566. PPIase_FKBP.
IPR001179. PPIase_FKBP_dom.
[Graphical view ]
PANTHERi PTHR10516. PTHR10516. 1 hit.
Pfami PF00254. FKBP_C. 1 hit.
[Graphical view ]
PROSITEi PS50059. FKBP_PPIASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Complete genome sequence of Thermus thermophilus HB8."
    Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
    Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HB8 / ATCC 27634 / DSM 579.
  2. "Crystal structure determination and functional characterization of the metallochaperone SlyD from Thermus thermophilus."
    Low C., Neumann P., Tidow H., Weininger U., Haupt C., Friedrich-Epler B., Scholz C., Stubbs M.T., Balbach J.
    J. Mol. Biol. 398:375-390(2010) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (2.41 ANGSTROMS) IN COMPLEX WITH NICKEL; SUCCINATE AND ZINC.

Entry informationi

Entry nameiQ5SLE7_THET8
AccessioniPrimary (citable) accession number: Q5SLE7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: September 3, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi