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Protein
Submitted name:

Oxidoreductase, short-chain dehydrogenase/reductase family

Gene

TTHA0369

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei84NAD; via carbonyl oxygenCombined sources1
Binding sitei134NAD; via carbonyl oxygenCombined sources1
Binding sitei149NADCombined sources1
Binding sitei153NADCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi16 – 18NADCombined sources3
Nucleotide bindingi37 – 39NADCombined sources3
Nucleotide bindingi56 – 58NADCombined sources3
Nucleotide bindingi179 – 184NADCombined sources6

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

NADCombined sources, Nucleotide-bindingCombined sources

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-383-MONOMER.
BRENDAi1.1.1.121. 7852.

Names & Taxonomyi

Protein namesi
Submitted name:
Oxidoreductase, short-chain dehydrogenase/reductase familyImported
Gene namesi
Ordered Locus Names:TTHA0369Imported
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA0369.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2D1YX-ray1.65A/B/C/D1-256[»]
ProteinModelPortaliQ5SLC4.
SMRiQ5SLC4.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5SLC4.

Family & Domainsi

Phylogenomic databases

eggNOGiENOG41061TZ. Bacteria.
COG1028. LUCA.
OMAiGFERTID.
PhylomeDBiQ5SLC4.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SLC4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLFAGKGVL VTGGARGIGR AIAQAFAREG ALVALCDLRP EGKEVAEAIG
60 70 80 90 100
GAFFQVDLED ERERVRFVEE AAYALGRVDV LVNNAAIAAP GSALTVRLPE
110 120 130 140 150
WRRVLEVNLT APMHLSALAA REMRKVGGGA IVNVASVQGL FAEQENAAYN
160 170 180 190 200
ASKGGLVNLT RSLALDLAPL RIRVNAVAPG AIATEAVLEA IALSPDPERT
210 220 230 240 250
RRDWEDLHAL RRLGKPEEVA EAVLFLASEK ASFITGAILP VDGGMTASFM

MAGRPV
Length:256
Mass (Da):26,961
Last modified:December 21, 2004 - v1
Checksum:i227E4CAECAC769BA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70192.1.
RefSeqiWP_011172461.1. NC_006461.1.
YP_143635.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70192; BAD70192; BAD70192.
GeneIDi3168644.
KEGGittj:TTHA0369.
PATRICi23955708. VBITheThe93045_0369.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70192.1.
RefSeqiWP_011172461.1. NC_006461.1.
YP_143635.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2D1YX-ray1.65A/B/C/D1-256[»]
ProteinModelPortaliQ5SLC4.
SMRiQ5SLC4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi300852.TTHA0369.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD70192; BAD70192; BAD70192.
GeneIDi3168644.
KEGGittj:TTHA0369.
PATRICi23955708. VBITheThe93045_0369.

Phylogenomic databases

eggNOGiENOG41061TZ. Bacteria.
COG1028. LUCA.
OMAiGFERTID.
PhylomeDBiQ5SLC4.

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-383-MONOMER.
BRENDAi1.1.1.121. 7852.

Miscellaneous databases

EvolutionaryTraceiQ5SLC4.

Family and domain databases

Gene3Di3.40.50.720. 1 hit.
InterProiIPR016040. NAD(P)-bd_dom.
IPR020904. Sc_DH/Rdtase_CS.
IPR002347. SDR_fam.
[Graphical view]
PANTHERiPTHR24322. PTHR24322. 2 hits.
PRINTSiPR00081. GDHRDH.
PR00080. SDRFAMILY.
SUPFAMiSSF51735. SSF51735. 1 hit.
PROSITEiPS00061. ADH_SHORT. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SLC4_THET8
AccessioniPrimary (citable) accession number: Q5SLC4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 2, 2016
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.