TTHA0533

Functionⁱ

Sites

Feature key	Position(s)	DescriptionActions	Length
Binding siteⁱ	8	S-adenosyl-L-homocysteineCombined sources	1
Binding siteⁱ	8	S-adenosyl-L-methionineCombined sources	1
Binding siteⁱ	207	S-adenosyl-L-homocysteineCombined sources	1
Binding siteⁱ	207	S-adenosyl-L-methionineCombined sources	1
Binding siteⁱ	216	S-adenosyl-L-homocysteineCombined sources	1
Binding siteⁱ	216	S-adenosyl-L-methionineCombined sources	1
Binding siteⁱ	241	S-adenosyl-L-homocysteine; via carbonyl oxygenCombined sources	1
Binding siteⁱ	241	S-adenosyl-L-methionine; via carbonyl oxygenCombined sources	1
Binding siteⁱ	307	S-adenosyl-L-homocysteineCombined sources	1
Binding siteⁱ	307	S-adenosyl-L-methionineCombined sources	1

GO - Molecular functionⁱ

nucleic acid binding Source: InterPro
rRNA (adenine-N6,N6-)-dimethyltransferase activity Source: InterPro

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	MethyltransferaseSAAS annotationImported, Transferase
Biological process	rRNA processingSAAS annotation
Ligand	S-adenosyl-L-methionineCombined sources

Enzyme and pathway databases

BioCycⁱ	TTHE300852:G1GKC-550-MONOMER

BioCycⁱ

TTHE300852:G1GKC-550-MONOMER

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Probable ribosomal RNA small subunit methyltransferaseImported
Gene namesⁱ	Ordered Locus Names:TTHA0533Imported
Organismⁱ	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifierⁱ	300852 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Bacteria › Terrabacteria group › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus › Thermus thermophilus
Proteomesⁱ	UP000000532 Componentⁱ: Chromosome

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	300852.TTHA0533

STRINGⁱ

300852.TTHA0533

Structureⁱ

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2ZUL	X-ray	1.80	A	1-375	[»]
	2ZWV	X-ray	2.00	A	1-375	[»]
	3DMF	X-ray	1.58	A	1-375	[»]
	3DMG	X-ray	1.55	A	1-375	[»]
	3DMH	X-ray	1.55	A	1-375	[»]
ProteinModelPortalⁱ	Q5SKW0
SMRⁱ	Q5SKW0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	Q5SKW0

EvolutionaryTraceⁱ

Q5SKW0

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	197 – 368	MTSInterPro annotationAdd BLAST		172

Region

Feature key	Position(s)	DescriptionActions	Length
Regionⁱ	262 – 263	S-adenosyl-L-homocysteine bindingCombined sources	2
Regionⁱ	262 – 263	S-adenosyl-L-methionine bindingCombined sources	2
Regionⁱ	288 – 289	S-adenosyl-L-homocysteine bindingCombined sources	2
Regionⁱ	288 – 289	S-adenosyl-L-methionine bindingCombined sources	2

Phylogenomic databases

eggNOGⁱ	ENOG4107S8D Bacteria COG2813 LUCA
HOGENOMⁱ	HOG000099293
KEGG Orthology (KO) More...KOⁱ	K00564
OMAⁱ	TNPPFHV
PhylomeDBⁱ	Q5SKW0

Family and domain databases

InterProⁱ	View protein in InterPro IPR002052 DNA_methylase_N6_adenine_CS IPR020596 rRNA_Ade_Mease_Trfase_CS IPR029063 SAM-dependent_MTases IPR007848 Small_mtfrase_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05175 MTS, 1 hit
SUPFAMⁱ	SSF53335 SSF53335, 2 hits
PROSITEⁱ	View protein in PROSITE PS00092 N6_MTASE, 1 hit PS01131 RRNA_A_DIMETH, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5SKW0-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSLTREAYHR LTPLPHPGGR LFIKPGARGY RDPVHDLLQK TVEPFGERAL 
        60         70         80         90        100
DLNPGVGWGS LPLEGRMAVE RLETSRAAFR CLTASGLQAR LALPWEAAAG 
       110        120        130        140        150
AYDLVVLALP AGRGTAYVQA SLVAAARALR MGGRLYLAGD KNKGFERYFK 
       160        170        180        190        200
EARALLGYGV VVRREGPYRV ALLEKEKEAP PLPSLWRAFS ARILGAEYTF 
       210        220        230        240        250
HHLPGVFSAG KVDPASLLLL EALQERLGPE GVRGRQVLDL GAGYGALTLP 
       260        270        280        290        300
LARMGAEVVG VEDDLASVLS LQKGLEANAL KAQALHSDVD EALTEEARFD 
       310        320        330        340        350
IIVTNPPFHV GGAVILDVAQ AFVNVAAARL RPGGVFFLVS NPFLKYEPLL 
       360        370 
EEKFGAFQTL KVAEYKVLFA EKRGR

Length:375

Mass (Da):40,656

Last modified:December 21, 2004 - v1

Checksum:ⁱ7EF362A795A93C55

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AP008226 Genomic DNA Translation: BAD70356.1
NCBI Reference Sequences More...RefSeqⁱ	WP_011228006.1, NC_006461.1 YP_143799.1, NC_006461.1

Genome annotation databases

EnsemblBacteriaⁱ	BAD70356; BAD70356; BAD70356
GeneIDⁱ	3169440
KEGGⁱ	ttj:TTHA0533
PATRICⁱ	fig\|300852.9.peg.532

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5SKW0	UPI000181CC60 H9ZSW1 Q72L94 UPI0003A1B27C Q9WX77 H7GFE4 F6DEK4	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Thermus thermophilus JL-18 Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) Thermus thermophilus Thermus parvatiensis Thermus thermophilus (strain SG0.5JP17-16)	375	UniRef90_Q5SKW0	Cluster: Probable ribosomal RNA small subunit methyltransferase	8

Protein	Similar proteins	Organisms	Length	Cluster ID	Cluster name	Size
Q5SKW0	UPI000181CC60 H9ZSW1 Q72L94 UPI0003A1B27C Q9WX77 H7GFE4 F6DEK4	Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) Thermus thermophilus JL-18 Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) Thermus thermophilus Thermus parvatiensis Thermus thermophilus (strain SG0.5JP17-16)	375	UniRef50_Q5SKW0	Cluster: Probable ribosomal RNA small subunit methyltransferase	8

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AP008226 Genomic DNA Translation: BAD70356.1
NCBI Reference Sequences More...RefSeqⁱ	WP_011228006.1, NC_006461.1 YP_143799.1, NC_006461.1

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2ZUL	X-ray	1.80	A	1-375	[»]
	2ZWV	X-ray	2.00	A	1-375	[»]
	3DMF	X-ray	1.58	A	1-375	[»]
	3DMG	X-ray	1.55	A	1-375	[»]
	3DMH	X-ray	1.55	A	1-375	[»]
ProteinModelPortalⁱ	Q5SKW0
SMRⁱ	Q5SKW0
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	300852.TTHA0533

STRINGⁱ

300852.TTHA0533

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

EnsemblBacteriaⁱ	BAD70356; BAD70356; BAD70356
GeneIDⁱ	3169440
KEGGⁱ	ttj:TTHA0533
PATRICⁱ	fig\|300852.9.peg.532

Phylogenomic databases

eggNOGⁱ	ENOG4107S8D Bacteria COG2813 LUCA
HOGENOMⁱ	HOG000099293
KEGG Orthology (KO) More...KOⁱ	K00564
OMAⁱ	TNPPFHV
PhylomeDBⁱ	Q5SKW0

Enzyme and pathway databases

BioCycⁱ	TTHE300852:G1GKC-550-MONOMER

BioCycⁱ

TTHE300852:G1GKC-550-MONOMER

Miscellaneous databases

EvolutionaryTraceⁱ	Q5SKW0

EvolutionaryTraceⁱ

Q5SKW0

Family and domain databases

InterProⁱ	View protein in InterPro IPR002052 DNA_methylase_N6_adenine_CS IPR020596 rRNA_Ade_Mease_Trfase_CS IPR029063 SAM-dependent_MTases IPR007848 Small_mtfrase_dom
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF05175 MTS, 1 hit
SUPFAMⁱ	SSF53335 SSF53335, 2 hits
PROSITEⁱ	View protein in PROSITE PS00092 N6_MTASE, 1 hit PS01131 RRNA_A_DIMETH, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5SKW0_THET8
Accessionⁱ	Q5SKW0Primary (citable) accession number: Q5SKW0
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 21, 2004
	Last sequence update:	December 21, 2004
	Last modified:	February 28, 2018
	This is version 94 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structureCombined sources, Complete proteome, Reference proteomeImported

UniProtKB - Q5SKW0 (Q5SKW0_THET8)

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Probable ribosomal RNA small subunit methyltransferase

Select a section on the left to see content.

Functionⁱ

Sites

GO - Molecular functionⁱ

Keywordsⁱ

Enzyme and pathway databases

Names & Taxonomyⁱ

Interactionⁱ

Protein-protein interaction databases

Structureⁱ

3D structure databases

Miscellaneous databases

Family & Domainsⁱ

Domains and Repeats

Region

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5SKW0 (Q5SKW0_THET8)

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Probable ribosomal RNA small subunit methyltransferase

TTHA0533

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

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Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ