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Protein
Submitted name:

Probable ribosomal RNA small subunit methyltransferase

Gene

TTHA0533

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei8S-adenosyl-L-homocysteineCombined sources1
Binding sitei207S-adenosyl-L-homocysteineCombined sources1
Metal bindingi216Iron-sulfur (4Fe-4S-S-AdoMet)Combined sources1
Binding sitei216S-adenosyl-L-homocysteineCombined sources1
Metal bindingi241Iron-sulfur (4Fe-4S-S-AdoMet); via carbonyl oxygenCombined sources1
Binding sitei241S-adenosyl-L-homocysteine; via carbonyl oxygenCombined sources1
Metal bindingi262Iron-sulfur (4Fe-4S-S-AdoMet)Combined sources1
Metal bindingi288Iron-sulfur (4Fe-4S-S-AdoMet)Combined sources1
Metal bindingi289Iron-sulfur (4Fe-4S-S-AdoMet); via amide nitrogenCombined sources1
Binding sitei307S-adenosyl-L-homocysteineCombined sources1

GO - Molecular functioni

Keywordsi

Molecular functionMethyltransferaseSAAS annotationImported, Transferase
Biological processrRNA processingSAAS annotation
Ligand4Fe-4SCombined sources, Iron, Iron-sulfur, Metal-binding

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-546-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Probable ribosomal RNA small subunit methyltransferaseImported
Gene namesi
Ordered Locus Names:TTHA0533Imported
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA0533.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2ZULX-ray1.80A1-375[»]
2ZWVX-ray2.00A1-375[»]
3DMFX-ray1.58A1-375[»]
3DMGX-ray1.55A1-375[»]
3DMHX-ray1.55A1-375[»]
ProteinModelPortaliQ5SKW0.
SMRiQ5SKW0.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5SKW0.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini197 – 368MTSInterPro annotationAdd BLAST172

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni262 – 263S-adenosyl-L-homocysteine bindingCombined sources2
Regioni288 – 289S-adenosyl-L-homocysteine bindingCombined sources2

Phylogenomic databases

eggNOGiENOG4107S8D. Bacteria.
COG2813. LUCA.
HOGENOMiHOG000099293.
KOiK00564.
OMAiTNPPFHV.
PhylomeDBiQ5SKW0.

Family and domain databases

InterProiView protein in InterPro
IPR002052. DNA_methylase_N6_adenine_CS.
IPR020596. rRNA_Ade_Mease_Trfase_CS.
IPR029063. SAM-dependent_MTases.
IPR007848. Small_mtfrase_dom.
PfamiView protein in Pfam
PF05175. MTS. 1 hit.
SUPFAMiSSF53335. SSF53335. 2 hits.
PROSITEiView protein in PROSITE
PS00092. N6_MTASE. 1 hit.
PS01131. RRNA_A_DIMETH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q5SKW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLTREAYHR LTPLPHPGGR LFIKPGARGY RDPVHDLLQK TVEPFGERAL
60 70 80 90 100
DLNPGVGWGS LPLEGRMAVE RLETSRAAFR CLTASGLQAR LALPWEAAAG
110 120 130 140 150
AYDLVVLALP AGRGTAYVQA SLVAAARALR MGGRLYLAGD KNKGFERYFK
160 170 180 190 200
EARALLGYGV VVRREGPYRV ALLEKEKEAP PLPSLWRAFS ARILGAEYTF
210 220 230 240 250
HHLPGVFSAG KVDPASLLLL EALQERLGPE GVRGRQVLDL GAGYGALTLP
260 270 280 290 300
LARMGAEVVG VEDDLASVLS LQKGLEANAL KAQALHSDVD EALTEEARFD
310 320 330 340 350
IIVTNPPFHV GGAVILDVAQ AFVNVAAARL RPGGVFFLVS NPFLKYEPLL
360 370
EEKFGAFQTL KVAEYKVLFA EKRGR
Length:375
Mass (Da):40,656
Last modified:December 21, 2004 - v1
Checksum:i7EF362A795A93C55
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70356.1.
RefSeqiWP_011228006.1. NC_006461.1.
YP_143799.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70356; BAD70356; BAD70356.
GeneIDi3169440.
KEGGittj:TTHA0533.
PATRICifig|300852.9.peg.532.

Similar proteinsi

Entry informationi

Entry nameiQ5SKW0_THET8
AccessioniPrimary (citable) accession number: Q5SKW0
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: August 30, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported