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Q5SKL7 (CAPP_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoenolpyruvate carboxylase

Short name=PEPC
Short name=PEPCase
EC=4.1.1.31
Gene names
Name:ppc
Ordered Locus Names:TTHA0626
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length858 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle By similarity. HAMAP-Rule MF_00595

Catalytic activity

Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + HCO3-. HAMAP-Rule MF_00595

Cofactor

Magnesium By similarity. HAMAP-Rule MF_00595

Sequence similarities

Belongs to the PEPCase type 1 family.

Ontologies

Keywords
   Biological processCarbon dioxide fixation
   LigandMagnesium
   Molecular functionLyase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processcarbon fixation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

oxaloacetate metabolic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

tricarboxylic acid cycle

Inferred from electronic annotation. Source: InterPro

   Molecular_functionmagnesium ion binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

phosphoenolpyruvate carboxylase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 858858Phosphoenolpyruvate carboxylase HAMAP-Rule MF_00595
PRO_0000166645

Sites

Active site1451 By similarity
Active site5311 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q5SKL7 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: D93E356DE0BB036F

FASTA85896,534
        10         20         30         40         50         60 
MSQDPFALLK AEVDLLGRLL GEAIRTLSGE RFFALVEEVR ALAKARRQGD EAAGEALLAR 

        70         80         90        100        110        120 
VEGLSTEEAE ALVRAFTHYF HLVNLAEERH RVRVNRLRAQ AETLESPRPE GFLALAKALK 

       130        140        150        160        170        180 
ERGLSLEEAE AHLNRLELLL TFTAHPTETR RRTLRHHLEA LQRELEAGDR ERLAARVALL 

       190        200        210        220        230        240 
YGTEEVRKAR PTVEDEIKGG LYYLPTTLWE AVPRVVAGLE AALERVYGRR PRLKSPVRFR 

       250        260        270        280        290        300 
SWIGGDRDGN PFVTPEVTAF AGRYAREVAR RRFLEALEDL VRDLSLAEAR VPVPREVRER 

       310        320        330        340        350        360 
GEGVERFMGE PYRRYFAALY RALEREEATT EGLLAALKAA ERGLREVGLG RVAEAFLDPL 

       370        380        390        400        410        420 
EARLSAFGLE LAPLDLREES GRLLEAAAEL LRVGGVHPDF LALPQEERER LLTEELKTAR 

       430        440        450        460        470        480 
PLLPVGEAPE GEALRVALGA LKAWRDKGAH VVSMTHHPED LLAVFLLARE VGLYRPGRPL 

       490        500        510        520        530        540 
PFDVVPLFET LEDLRRAPGV LRRLLENPVF LAHARGRGGV EVMIGYSDSN KDAGFLMANL 

       550        560        570        580        590        600 
ALYEAQEALS RVGEEVGLPV YFFHGRGTST ARGGGPAGRA IASLPPRSVG RRIRLTEQGE 

       610        620        630        640        650        660 
ALADRYSHPD LAVRHLEQML YHFALAALGP GQEPEARWRE ALAQAAEEST RRYRALLQEE 

       670        680        690        700        710        720 
GFFDFFEAFT PIREIGELPI ASRPVYRRGR VRDIRDLRAI PWVMAWTQVR VLLPGWYGLS 

       730        740        750        760        770        780 
ALEELPLDLL REMYRGWPFF ASTLEAAAMA LAKADMGVAR LYLRLVPEPL RFFYRRLAEE 

       790        800        810        820        830        840 
HARTVALLEA VFQAPLLHNQ RTLERQIRLR NPYVDPINIV QVELLRRYRA PGGKEDEALR 

       850 
RALLLSILGV AAGLRNAG 

« Hide

References

[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AP008226 Genomic DNA. Translation: BAD70449.1.
RefSeqYP_143892.1. NC_006461.1.

3D structure databases

ProteinModelPortalQ5SKL7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING300852.TTHA0626.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD70449; BAD70449; BAD70449.
GeneID3169755.
KEGGttj:TTHA0626.
PATRIC23956231. VBITheThe93045_0624.

Phylogenomic databases

eggNOGCOG2352.
HOGENOMHOG000238647.
KOK01595.
OMAELSTISC.
OrthoDBEOG6TJ7T8.
PhylomeDBQ5SKL7.

Enzyme and pathway databases

BioCycTTHE300852:GH8R-653-MONOMER.

Family and domain databases

HAMAPMF_00595. PEPcase_type1.
InterProIPR021135. PEP_COase.
IPR018129. PEP_COase_AS.
IPR022805. PEP_COase_bac/pln-type.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]
PfamPF00311. PEPcase. 1 hit.
[Graphical view]
PRINTSPR00150. PEPCARBXLASE.
SUPFAMSSF51621. SSF51621. 1 hit.
PROSITEPS00781. PEPCASE_1. 1 hit.
PS00393. PEPCASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCAPP_THET8
AccessionPrimary (citable) accession number: Q5SKL7
Entry history
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: December 21, 2004
Last modified: July 9, 2014
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families