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Protein
Submitted name:

Uncharacterized protein

Gene

TTHA0667

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei11S-adenosyl-L-homocysteine; via carbonyl oxygenCombined sources1
Binding sitei160S-adenosyl-L-homocysteine; via amide nitrogenCombined sources1
Binding sitei189S-adenosyl-L-homocysteine; via amide nitrogen and carbonyl oxygenCombined sources1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

MethyltransferaseUniRule annotationSAAS annotation, Transferase

Keywords - Ligandi

S-adenosyl-L-methionineSAAS annotation

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-681-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Ordered Locus Names:TTHA0667Imported
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA0667.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1V9AX-ray2.00A/B2-240[»]
1VA0X-ray1.97A/B2-240[»]
ProteinModelPortaliQ5SKH6.
SMRiQ5SKH6.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5SKH6.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 205TP_methylaseInterPro annotationAdd BLAST203

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni84 – 90S-adenosyl-L-homocysteine bindingCombined sources7
Regioni114 – 115S-adenosyl-L-homocysteine bindingCombined sources2
Regioni214 – 215S-adenosyl-L-homocysteine bindingCombined sources2

Sequence similaritiesi

Belongs to the precorrin methyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CB8. Bacteria.
COG0007. LUCA.
HOGENOMiHOG000290519.
KOiK02303.
OMAiRVWIAKE.
PhylomeDBiQ5SKH6.

Family and domain databases

Gene3Di3.30.950.10. 1 hit.
3.40.1010.10. 1 hit.
InterProiIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR006366. CobA/CysG_C.
IPR003043. Uropor_MeTrfase_CS.
[Graphical view]
PfamiPF00590. TP_methylase. 1 hit.
[Graphical view]
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR01469. cobA_cysG_Cterm. 1 hit.
PROSITEiPS00839. SUMT_1. 1 hit.
PS00840. SUMT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q5SKH6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRVYLVGAG PGDPELLTLK AYRLLKEAPV VLYDRLVDER VLALAPGEKV
60 70 80 90 100
YVGKEEGESE KQEEIHRLLL RHARAHPFVV RLKGGDPMVF GRGGEEVLFL
110 120 130 140 150
LRHGVPVEVV PGVTSLLASG LPLTHRGLAH GFAAVSGVLE GGGYPDLRPF
160 170 180 190 200
ARVPTLVVLM GVGRRVWIAK ELLRLGRDPR EPTLFVERAS TPKERRVHAR
210 220 230 240
LEEVAEGKVE VRPPALWILG EVVRVFAEKE APVDALALGG
Length:240
Mass (Da):26,234
Last modified:December 21, 2004 - v1
Checksum:i0FA4E4E186F7B73F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70490.1.
RefSeqiWP_011228110.1. NC_006461.1.
YP_143933.1. NC_006461.1.

Genome annotation databases

EnsemblBacteriaiBAD70490; BAD70490; BAD70490.
GeneIDi3168431.
KEGGittj:TTHA0667.
PATRICi23956311. VBITheThe93045_0661.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA. Translation: BAD70490.1.
RefSeqiWP_011228110.1. NC_006461.1.
YP_143933.1. NC_006461.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1V9AX-ray2.00A/B2-240[»]
1VA0X-ray1.97A/B2-240[»]
ProteinModelPortaliQ5SKH6.
SMRiQ5SKH6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi300852.TTHA0667.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAD70490; BAD70490; BAD70490.
GeneIDi3168431.
KEGGittj:TTHA0667.
PATRICi23956311. VBITheThe93045_0661.

Phylogenomic databases

eggNOGiENOG4105CB8. Bacteria.
COG0007. LUCA.
HOGENOMiHOG000290519.
KOiK02303.
OMAiRVWIAKE.
PhylomeDBiQ5SKH6.

Enzyme and pathway databases

BioCyciTTHE300852:GH8R-681-MONOMER.

Miscellaneous databases

EvolutionaryTraceiQ5SKH6.

Family and domain databases

Gene3Di3.30.950.10. 1 hit.
3.40.1010.10. 1 hit.
InterProiIPR000878. 4pyrrol_Mease.
IPR014777. 4pyrrole_Mease_sub1.
IPR014776. 4pyrrole_Mease_sub2.
IPR006366. CobA/CysG_C.
IPR003043. Uropor_MeTrfase_CS.
[Graphical view]
PfamiPF00590. TP_methylase. 1 hit.
[Graphical view]
SUPFAMiSSF53790. SSF53790. 1 hit.
TIGRFAMsiTIGR01469. cobA_cysG_Cterm. 1 hit.
PROSITEiPS00839. SUMT_1. 1 hit.
PS00840. SUMT_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ5SKH6_THET8
AccessioniPrimary (citable) accession number: Q5SKH6
Entry historyi
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: November 2, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.