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Protein

Ribosome-binding factor A

Gene

rbfA

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes) (PubMed:17996707). Required for efficient processing of 16S rRNA. Probably interacts with the 5'-terminal helix region of 16S rRNA, bringing together different domains of the 30S ribosomal subunit which aids assembly (PubMed:17996707).1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRNA-binding, rRNA-binding
Biological processRibosome biogenesis

Enzyme and pathway databases

BioCyciTTHE300852:G1GKC-926-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosome-binding factor A1 Publication
Alternative name(s):
30S ribosome-binding protein
Gene namesi
Name:rbfA1 Publication
Ordered Locus Names:TTHA0907
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004389831 – 95Ribosome-binding factor AAdd BLAST95

Interactioni

Subunit structurei

Interacts with the 30S ribosomal subunit as a monomer, binding in a position overlapping the sites of the A and P site tRNAs, and displacing segments of the 16S rRNA. Probably contacts 16S rRNA and ribosomal protein S9 and S13.1 Publication

Protein-protein interaction databases

STRINGi300852.TTHA0907

Structurei

Secondary structure

195
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi5 – 21Combined sources17
Helixi26 – 28Combined sources3
Beta strandi32 – 38Combined sources7
Beta strandi42 – 50Combined sources9
Helixi55 – 64Combined sources10
Helixi66 – 74Combined sources9
Beta strandi84 – 89Combined sources6
Helixi90 – 92Combined sources3

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2DYJX-ray1.84A/B1-95[»]
2R1Celectron microscopy12.50A1-95[»]
ProteinModelPortaliQ5SJV1
SMRiQ5SJV1
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5SJV1

Family & Domainsi

Sequence similaritiesi

Belongs to the RbfA family.Curated

Phylogenomic databases

HOGENOMiHOG000218325
KOiK02834
OMAiRTPTLEF

Family and domain databases

Gene3Di3.30.300.20, 1 hit
HAMAPiMF_00003 RbfA, 1 hit
InterProiView protein in InterPro
IPR015946 KH_dom-like_a/b
IPR000238 RbfA
IPR023799 RbfA_dom_sf
PANTHERiPTHR33515 PTHR33515, 1 hit
PfamiView protein in Pfam
PF02033 RBFA, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD007327 Rib_bd_factA, 1 hit
SUPFAMiSSF89919 SSF89919, 1 hit

Sequencei

Sequence statusi: Complete.

Q5SJV1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAYGKAHLEA QLKRALAEEI QALEDPRLFL LTVEAVRLSK DGSVLSVYVE
60 70 80 90
AFREEEGALR ALSRAERRLV AALARRVRMR RLPRLEFLPW RASPA
Length:95
Mass (Da):10,857
Last modified:December 21, 2004 - v1
Checksum:i2807A8979E74A3C9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA Translation: BAD70730.1
RefSeqiWP_011172996.1, NC_006461.1
YP_144173.1, NC_006461.1

Genome annotation databases

EnsemblBacteriaiBAD70730; BAD70730; BAD70730
GeneIDi3169952
KEGGittj:TTHA0907
PATRICifig|300852.9.peg.899

Similar proteinsi

Entry informationi

Entry nameiRBFA_THET8
AccessioniPrimary (citable) accession number: Q5SJV1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 15, 2017
Last sequence update: December 21, 2004
Last modified: March 28, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

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