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Q5SJE8 (TAL_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable transaldolase
EC=2.2.1.2
Gene names
Name:tal
Ordered Locus Names:TTHA1066
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length223 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway By similarity. HAMAP MF_00494

Catalytic activity

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate. HAMAP MF_00494

Pathway

Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3. HAMAP MF_00494

Subcellular location

Cytoplasm By similarity HAMAP MF_00494.

Sequence similarities

Belongs to the transaldolase family. Type 3B subfamily.

Ontologies

Keywords
   Biological processPentose shunt
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processpentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionsedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 223223Probable transaldolase HAMAP MF_00494
PRO_1000126370

Sites

Active site921 By similarity

Secondary structure

1 ....................................... 223
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q5SJE8 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: F5C9D213FB1E2E47

FASTA22324,023
        10         20         30         40         50         60 
MELYLDTASL EEIREIAAWG VLSGVTTNPT LVAKAFAAKG EALTEEAFAA HLRAICETVG 

        70         80         90        100        110        120 
GPVSAEVTAL EAEAMVAEGR RLAAIHPNIV VKLPTTEEGL KACKRLSAEG IKVNMTLIFS 

       130        140        150        160        170        180 
ANQALLAARA GASYVSPFLG RVDDISWDGG ELLREIVEMI QVQDLPVKVI AASIRHPRHV 

       190        200        210        220 
TEAALLGADI ATMPHAVFKQ LLKHPLTDIG LKRFLEDWEK VKP

« Hide

References

[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008226 Genomic DNA. Translation: BAD70889.1.
RefSeqYP_144332.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1WX0X-ray2.27A/B/C/D/E/F/G/H/I/J1-223[»]
ProteinModelPortalQ5SJE8.
SMRQ5SJE8. Positions 1-211.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5SJE8.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3168258.
GenomeReviewsGene locus TTHA1066 in contig AP008226_GR.
KEGGttj:TTHA1066.
NMPDRfig|300852.3.peg.1203.
PATRIC23957092. VBITheThe93045_1046.

Phylogenomic databases

eggNOGCOG0176.
HOGENOMHBG533000.
OMAKVNVTLC.
PhylomeDBQ5SJE8.
ProtClustDBPRK01362.

Enzyme and pathway databases

BioCycTTHE300852:TTHA1066-MONOMER.

Family and domain databases

HAMAPMF_00494. Transaldolase_3b.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR001585. Transaldolase.
IPR004731. Transaldolase_3A/3B.
IPR022999. Transaldolase_3B.
IPR018225. Transaldolase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK00616.
PANTHERPTHR10683. Transaldolase. 1 hit.
PfamPF00923. Transaldolase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00875. Fsa_talC_mipB. 1 hit.
PROSITEPS01054. TRANSALDOLASE_1. 1 hit.
PS00958. TRANSALDOLASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTAL_THET8
AccessionPrimary (citable) accession number: Q5SJE8
Entry history
Integrated into UniProtKB/Swiss-Prot: April 14, 2009
Last sequence update: December 21, 2004
Last modified: January 25, 2012
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

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