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Protein

Cell division protein FtsZ

Gene

ftsZ

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei131GTPUniRule annotation1
Binding sitei135GTPUniRule annotation1
Binding sitei179GTPUniRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 17GTPUniRule annotation5
Nucleotide bindingi100 – 102GTPUniRule annotation3

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell cycle, Cell division, SeptationUniRule annotation
LigandGTP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciTTHE300852:G1GKC-1096-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Cell division protein FtsZUniRule annotation
Gene namesi
Name:ftsZUniRule annotation
Ordered Locus Names:TTHA1089Imported
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA1089

Structurei

3D structure databases

ProteinModelPortaliQ5SJC5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 197TubulinInterPro annotationAdd BLAST193
Domaini199 – 317Tubulin_CInterPro annotationAdd BLAST119

Sequence similaritiesi

Belongs to the FtsZ family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CDK Bacteria
COG0206 LUCA
HOGENOMiHOG000049094
KOiK03531
OMAiMRAVKGI
PhylomeDBiQ5SJC5

Family and domain databases

CDDicd02201 FtsZ_type1, 1 hit
Gene3Di3.40.50.1440, 1 hit
HAMAPiMF_00909 FtsZ, 1 hit
InterProiView protein in InterPro
IPR000158 Cell_div_FtsZ
IPR020805 Cell_div_FtsZ_CS
IPR024757 FtsZ_C
IPR008280 Tub_FtsZ_C
IPR018316 Tubulin/FtsZ_2-layer-sand-dom
IPR036525 Tubulin/FtsZ_GTPase_sf
IPR003008 Tubulin_FtsZ_GTPase
PfamiView protein in Pfam
PF12327 FtsZ_C, 1 hit
PF00091 Tubulin, 1 hit
PRINTSiPR00423 CELLDVISFTSZ
SMARTiView protein in SMART
SM00864 Tubulin, 1 hit
SM00865 Tubulin_C, 1 hit
SUPFAMiSSF52490 SSF52490, 1 hit
SSF55307 SSF55307, 1 hit
TIGRFAMsiTIGR00065 ftsZ, 1 hit
PROSITEiView protein in PROSITE
PS01134 FTSZ_1, 1 hit
PS01135 FTSZ_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5SJC5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEGAVIKVIG LGGAGNNAVN RMIEAGLSGV EFIAANTDAQ VLAKSLADHR
60 70 80 90 100
IQLGEKLTRG LGAGANPEIG EKAALEAEDL IAEALEGADL VFITAGMGGG
110 120 130 140 150
TGTGSAPVVA DIAKRLGALT VAVVTRPFSF EGPKRMRAAE EGIKKLKERV
160 170 180 190 200
DAMVVVQNDR LLSAVDKKMT LKDAFLIADR VLYHGVKGIT DVINLPGLIN
210 220 230 240 250
VDFADVKALL EGAGQVLMGI GAGRGENRVE EAAKSAIHSP LLERSIEGAK
260 270 280 290 300
RLLLNVVGSE ELSLMEAAEV VERIREATGH EDVDILYGVT YDERAQDELR
310 320 330 340 350
VILIAAGFAE STVVPRPARP VDFPTGHVDL TNYDIPAFIR YGDGDYPPRR

GN
Length:352
Mass (Da):37,237
Last modified:December 21, 2004 - v1
Checksum:iADA53505D3595F22
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA Translation: BAD70912.1
RefSeqiWP_011173163.1, NC_006461.1
YP_144355.1, NC_006461.1

Genome annotation databases

EnsemblBacteriaiBAD70912; BAD70912; BAD70912
GeneIDi3169986
KEGGittj:TTHA1089
PATRICifig|300852.9.peg.1069

Similar proteinsi

Entry informationi

Entry nameiQ5SJC5_THET8
AccessioniPrimary (citable) accession number: Q5SJC5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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