Q5SJ50 (Q5SJ50_THET8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Indole-3-glycerol phosphate synthase EMBL BAD70987.1

Gene names

Ordered Locus Names:

TTHA1164

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	254 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Catalytic activity	1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-C-(3-indolyl)-glycerol 3-phosphate + CO2 + H2O. SAAS SAAS013798
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5. SAAS SAAS013798

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis SAAS SAAS013798
Molecular function	Lyase SAAS SAAS013798
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	indole-3-glycerol-phosphate synthase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5SJ50 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: CFED2E4DFFC8E95B	FASTA	254	27,419
	10 20 30 40 50 60 MRPDLSRVPG VLGEIARKRA SEVAPYPLPE PPSVPSFKEA LLRPGLSVIA EVKRQSPSEG 70 80 90 100 110 120 LIREVDPVEA ALAYARGGAR AVSVLTEPHR FGGSLLDLKR VREAVDLPLL RKDFVVDPFM 130 140 150 160 170 180 LEEARAFGAS AALLIVALLG ELTGAYLEEA RRLGLEALVE VHTERELEIA LEAGAEVLGI 190 200 210 220 230 240 NNRDLATLHI NLETAPRLGR LARKRGFGGV LVAESGYSRK EELKALEGLF DAVLIGTSLM 250 RAPDLEAALR ELVG

References

[1]

"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008226 Genomic DNA. Translation: BAD70987.1.
RefSeq	YP_144430.1. NC_006461.1.
3D structure databases
ProteinModelPortal	Q5SJ50.
SMR	Q5SJ50. Positions 1-254.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5SJ50.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3168685.
GenomeReviews	Gene locus TTHA1164 in contig AP008226_GR.
KEGG	ttj:TTHA1164.
NMPDR	fig|300852.3.peg.1362.
PATRIC	23957289. VBITheThe93045_1144.
Phylogenomic databases
eggNOG	COG0134.
HOGENOM	HBG540956.
OMA	MRKDDVT.
PhylomeDB	Q5SJ50.
ProtClustDB	PRK00278.
Enzyme and pathway databases
BioCyc	TTHE300852:TTHA1164-MONOMER.
Family and domain databases
InterPro	IPR013785. Aldolase_TIM. IPR013798. Indole-3-glycerol_P_synth. IPR011060. RibuloseP-bd_barrel. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KO	K01609.
Pfam	PF00218. IGPS. 1 hit. [Graphical view]
SUPFAM	SSF51366. RibP_bind_barrel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q5SJ50_THET8

Accession

Primary (citable) accession number: Q5SJ50

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)