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Q5SIT4 (Q5SIT4_THET8) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 47. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesSubmitted name:
Putative uncharacterized protein TTHA1280 EMBL BAD71103.1
Gene names
Ordered Locus Names:TTHA1280
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length382 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subcellular location

Cytoplasm By similarity SAAS SAAS019614.

Ontologies

Keywords
   Biological processrRNA processing SAAS SAAS019614
   Cellular componentCytoplasm SAAS SAAS019614
   LigandS-adenosyl-L-methionine SAAS SAAS019614
   Molecular functionMethyltransferase SAAS SAAS019614
Transferase
   Technical term3D-structure PDB 2CWW PDB 1WXX PDB 1WXW
Complete proteome
Reference proteome
Gene Ontology (GO)
   Biological processrRNA processing

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionmethyltransferase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region265 – 2662S-adenosyl-L-homocysteine binding PDB 2CWW

Sites

Binding site2021S-adenosyl-L-homocysteine PDB 2CWW
Binding site2171S-adenosyl-L-homocysteine PDB 2CWW
Binding site2381S-adenosyl-L-homocysteine PDB 2CWW
Binding site2861S-adenosyl-L-homocysteine PDB 2CWW

Sequences

Sequence LengthMass (Da)Tools
Q5SIT4 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: A9535E02207F9C1E

FASTA38243,000
        10         20         30         40         50         60 
MRIQVNAKGA ARLLSRHLWV FRRDVVSGPE TPGLYPVYWG RRFLALALYN PHTDLAVRAY 

        70         80         90        100        110        120 
RFAPAEDPVA ALLENLAQAL ARREAVLRQD PEGGYRLVHA EGDLLPGLVV DYYAGHAVVQ 

       130        140        150        160        170        180 
ATAHAWEGLL PQVAEALRPH VQSVLAKNDA RTRELEGLPL YVRPLLGEVP ERVQVQEGRV 

       190        200        210        220        230        240 
RYLVDLRAGQ KTGAYLDQRE NRLYMERFRG ERALDVFSYA GGFALHLALG FREVVAVDSS 

       250        260        270        280        290        300 
AEALRRAEEN ARLNGLGNVR VLEANAFDLL RRLEKEGERF DLVVLDPPAF AKGKKDVERA 

       310        320        330        340        350        360 
YRAYKEVNLR AIKLLKEGGI LATASCSHHM TEPLFYAMVA EAAQDAHRLL RVVEKRGQPF 

       370        380 
DHPVLLNHPE THYLKFAVFQ VL

« Hide

References

« Hide 'large scale' references
[1]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.
[2]"Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine."
Pioszak A.A., Murayama K., Nakagawa N., Ebihara A., Kuramitsu S., Shirouzu M., Yokoyama S.
Acta Crystallogr. F 61:867-874(2005) [PubMed: 16511182] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (1.80 ANGSTROMS) IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AP008226 Genomic DNA. Translation: BAD71103.1.
RefSeqYP_144546.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1WXWX-ray2.55A/B/C/D1-382[»]
1WXXX-ray1.80A/B/C/D1-382[»]
2CWWX-ray2.60A/B1-382[»]
ProteinModelPortalQ5SIT4.
SMRQ5SIT4. Positions 1-382.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ5SIT4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3168447.
GenomeReviewsGene locus TTHA1280 in contig AP008226_GR.
KEGGttj:TTHA1280.
NMPDRfig|300852.3.peg.1533.
PATRIC23957523. VBITheThe93045_1259.

Phylogenomic databases

eggNOGCOG1092.
HOGENOMHBG411897.
OMAATAHAWE.
ProtClustDBCLSK738539.

Enzyme and pathway databases

BioCycTTHE300852:TTHA1280-MONOMER.

Family and domain databases

InterProIPR015947. PUA-like_domain.
IPR019614. SAM-dep_methyl-trfase.
[Graphical view]
KOK06969.
PfamPF10672. Methyltrans_SAM. 1 hit.
[Graphical view]
SUPFAMSSF88697. PUA-like. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ5SIT4_THET8
AccessionPrimary (citable) accession number: Q5SIT4
Entry history
Integrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: December 14, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info