Q5SIR5 (RPIA_THET8) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	TTHA1299

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	227 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 227	227	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158487

Sequences

	Sequence		Length	Mass (Da)
	Q5SIR5 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 87C350B18777FDB3	FASTA	227	24,067
	10 20 30 40 50 60 MERPLESYKK EAAHAAIAYV QDGMVVGLGT GSTARYAVLE LARRLREGEL KGVVGVPTSR 70 80 90 100 110 120 ATEELAKREG IPLVDLPPEG VDLAIDGADE IAPGLALIKG MGGALLREKI VERVAKEFIV 130 140 150 160 170 180 IADHTKKVPV LGRGPVPVEI VPFGYRATLK AIADLGGEPE LRMDGDEFYF TDGGHLIADC 190 200 210 220 RFGPIGDPLG LHRALLEIPG VVETGLFVGM ATRALVAGPF GVEELLP

References

[1]	"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008226 Genomic DNA. Translation: BAD71122.1.
RefSeq	YP_144565.1. NC_006461.1.
3D structure databases
ProteinModelPortal	Q5SIR5.
SMR	Q5SIR5. Positions 3-227.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5SIR5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3168636.
GenomeReviews	Gene locus TTHA1299 in contig AP008226_GR.
KEGG	ttj:TTHA1299.
NMPDR	fig|300852.3.peg.1552.
PATRIC	23957559. VBITheThe93045_1277.
Phylogenomic databases
eggNOG	COG0120.
HOGENOM	HBG515603.
OMA	GGDPEYR.
PhylomeDB	Q5SIR5.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	TTHE300852:TTHA1299-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_THET8

Accession

Primary (citable) accession number: Q5SIR5

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	December 21, 2004
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program