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Protein
Submitted name:

5'-nucleotidase

Gene

TTHA1328

Organism
Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi37Zinc 1Combined sources1
Metal bindingi39Zinc 1; via tele nitrogenCombined sources1
Metal bindingi83Zinc 1Combined sources1
Metal bindingi83Zinc 2Combined sources1
Metal bindingi115Zinc 2Combined sources1
Metal bindingi215Zinc 2Combined sources1
Metal bindingi238Zinc 2; via pros nitrogenCombined sources1
Metal bindingi240Zinc 1Combined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseUniRule annotation
LigandMetal-bindingCombined sources, Nucleotide-bindingUniRule annotation, ZincCombined sources

Enzyme and pathway databases

BioCyciTTHE300852:G1GKC-1332-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
5'-nucleotidaseImported
Gene namesi
Ordered Locus Names:TTHA1328Imported
OrganismiThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)Imported
Taxonomic identifieri300852 [NCBI]
Taxonomic lineageiBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus
Proteomesi
  • UP000000532 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi300852.TTHA1328

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2Z1AX-ray1.75A1-552[»]
ProteinModelPortaliQ5SIP1
SMRiQ5SIP1
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ5SIP1

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini31 – 241MetallophosInterPro annotationAdd BLAST211
Domaini333 – 4945_nucleotid_CInterPro annotationAdd BLAST162

Sequence similaritiesi

Belongs to the 5'-nucleotidase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CGH Bacteria
COG0737 LUCA
HOGENOMiHOG000247215
KOiK11751
OMAiMNTVCFD
PhylomeDBiQ5SIP1

Family and domain databases

Gene3Di3.60.21.10, 1 hit
3.90.780.10, 1 hit
InterProiView protein in InterPro
IPR008334 5'-Nucleotdase_C
IPR036907 5'-Nucleotdase_C_sf
IPR006146 5'-Nucleotdase_CS
IPR006179 5_nucleotidase/apyrase
IPR004843 Calcineurin-like_PHP_ApaH
IPR029052 Metallo-depent_PP-like
PANTHERiPTHR11575 PTHR11575, 1 hit
PfamiView protein in Pfam
PF02872 5_nucleotid_C, 1 hit
PF00149 Metallophos, 1 hit
PRINTSiPR01607 APYRASEFAMLY
SUPFAMiSSF55816 SSF55816, 1 hit
PROSITEiView protein in PROSITE
PS00785 5_NUCLEOTIDASE_1, 1 hit
PS00786 5_NUCLEOTIDASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q5SIP1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKRREVLQAG MALGGLAGLG RALAQGGFTL TLVHTNDTHA HLEPVELTLS
60 70 80 90 100
GEKTPVGGVA RRVALFDRVW ARAKNPLFLD AGDVFQGTLY FNQYRGLADR
110 120 130 140 150
YFMHRLRYRA MALGNHEFDL GPGPLADFLK GARFKVVSAN VDASREPRLK
160 170 180 190 200
GLFAPYAVVV VGGERVGIIG LTTPDTREIS NPGPTVAFLD PYESAQKAVY
210 220 230 240 250
ELLAKGVNKI VVLSHLGYGE DLKLARRLVG VQVIVGGHSH TLLGSFPHKE
260 270 280 290 300
LSPAGPYPTV VKNPEGKDVL VVQAWEWGKV VGLLEVTFDA KGELLAYKGE
310 320 330 340 350
ALLMTPEAAP EDFFAKEALL AYAQPVMALM QQVIAEAKVD LVGERAVVRR
360 370 380 390 400
RESNLGNLIT DGMLWKTRNA GTQIALQNGG GIRASIPKGP ITVGKVYEVL
410 420 430 440 450
PFGNTLVVMD LKGKEILAAL ENGVSQWENT AGRFLQVSGL RYAFDLSRPA
460 470 480 490 500
GSRVVRVEVK TEKGYVPLDL EATYRVVVNN FIANGGDGFT VLKEAQGYRV
510 520 530 540 550
DTGFSDAESF MDYLKELKVV EAGLEGRIEV LNEPKGERPA YFAYRVPGLV

GV
Length:552
Mass (Da):59,970
Last modified:December 21, 2004 - v1
Checksum:i0030AF05053DF3ED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008226 Genomic DNA Translation: BAD71151.1
RefSeqiWP_011228601.1, NC_006461.1
YP_144594.1, NC_006461.1

Genome annotation databases

EnsemblBacteriaiBAD71151; BAD71151; BAD71151
GeneIDi3167981
KEGGittj:TTHA1328
PATRICifig|300852.9.peg.1306

Similar proteinsi

Entry informationi

Entry nameiQ5SIP1_THET8
AccessioniPrimary (citable) accession number: Q5SIP1
Entry historyiIntegrated into UniProtKB/TrEMBL: December 21, 2004
Last sequence update: December 21, 2004
Last modified: March 28, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health