Q5SIK1 (Q5SIK1_THET8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Signal peptidase I RuleBase RU003993
EC=3.4.21.89 RuleBase RU003993

Gene names

Ordered Locus Names:

TTHA1368

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	268 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins. RuleBase RU003993
Sequence similarities	Belongs to the peptidase S26 family. RuleBase RU003989

Ontologies

Keywords
Molecular function	Hydrolase Protease RuleBase RU003988
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	integral to membrane Inferred from electronic annotation. Source: InterPro
Molecular function	serine-type peptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q5SIK1 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 895B1171AC3E776D	FASTA	268	30,495
	10 20 30 40 50 60 MKAFWDYLFK EWFRQVGEAL LVAFLVTTFV FTTVGVVGQS MYPTLRNGER VLVPKWETWL 70 80 90 100 110 120 VRLGFMEWRR GEIAILKPPE GTPFSTARFP VLGFSFRAFF IKRIVAVPGD EVYVDRGVVY 130 140 150 160 170 180 VNGKPLAETH ITDRITPWPD SFPGVCYEGG RLTRIVTQQG DFPVELLPAY LRPLKEMLLP 190 200 210 220 230 240 PSQETLARSE LGEVCEVGRI KLKPGYYFVM GDNRTLGGSE DSRTFGPIPV ERIAGRASFV 250 260 WWPVVVREEG GFRLNLRALA IPPAYRLE

References

[1]

"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008226 Genomic DNA. Translation: BAD71191.1.
RefSeq	YP_144634.1. NC_006461.1.
3D structure databases
ProteinModelPortal	Q5SIK1.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5SIK1.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3168586.
GenomeReviews	Gene locus TTHA1368 in contig AP008226_GR.
KEGG	ttj:TTHA1368.
NMPDR	fig|300852.3.peg.1647.
PATRIC	23957693. VBITheThe93045_1344.
Phylogenomic databases
eggNOG	COG0681.
HOGENOM	HBG596607.
OMA	NGQFIDE.
ProtClustDB	CLSK738696.
Enzyme and pathway databases
BioCyc	TTHE300852:TTHA1368-MONOMER.
Family and domain databases
InterPro	IPR000223. Pept_S26A_signal_pept_1. IPR019757. Pept_S26A_signal_pept_1_Lys-AS. IPR019756. Pept_S26A_signal_pept_1_Ser-AS. IPR019759. Peptidase_S24_S26. IPR015927. Peptidase_S24_S26A/B/C. IPR011056. Peptidase_S24_S26A/B/C_b-rbn. [Graphical view]
Gene3D	G3DSA:2.10.109.10. Pept_S24_S26_C. 2 hits.
KO	K03100.
Pfam	PF00717. Peptidase_S24. 1 hit. [Graphical view]
PRINTS	PR00727. LEADERPTASE.
SUPFAM	SSF51306. Pept_S24_S26_C. 1 hit.
TIGRFAMs	TIGR02227. Sigpep_I_bact. 1 hit.
PROSITE	PS00501. SPASE_I_1. 1 hit. PS00760. SPASE_I_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5SIK1_THET8

Accession

Primary (citable) accession number: Q5SIK1

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)