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Q5SIH3 (RSHX_THET8) Reviewed, UniProtKB/Swiss-Prot

Last modified January 22, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Web links·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
30S ribosomal protein Thx
Alternative name(s):
S31
Gene names
Name:rpsU
Ordered Locus Names:TTHA1396
OrganismThermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) [Reference proteome] [HAMAP]
Taxonomic identifier300852 [NCBI]
Taxonomic lineageBacteriaDeinococcus-ThermusDeinococciThermalesThermaceaeThermus

Protein attributes

Sequence length27 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Binds at the top of the head of the 30S subunit. It stabilizes a number of different RNA elements and thus is important for subunit structure.

Subunit structure

Part of the 30S ribosomal subunit. Ref.6 Ref.7 Ref.8 Ref.10 Ref.11 Ref.13 Ref.14

Sequence similarities

Belongs to the ribosomal protein S31e family.

Mass spectrometry

Molecular mass is 3206 Da from positions 2 - 27. Determined by MALDI. Ref.5

Ontologies

Keywords
   LigandRNA-binding
rRNA-binding
   Molecular functionRibonucleoprotein
Ribosomal protein
   Technical term3D-structure
Complete proteome
Direct protein sequencing
Reference proteome
Gene Ontology (GO)
   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionrRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Initiator methionine11Removed Ref.3 Ref.4
Chain2 – 272630S ribosomal protein Thx
PRO_0000217202

Secondary structure

...... 27
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q5SIH3 [UniParc].

Last modified January 23, 2007. Version 3.
Checksum: 85822DC5D8D8C604

FASTA273,337
        10         20 
MGKGDRRTRR GKIWRGTYGK YRPRKKK 

« Hide

References

« Hide 'large scale' references
[1]"On the characterization of the putative S20-thx operon of Thermus thermophilus."
Leontiadou F., Triantafillidou D., Choli-Papadopoulou T.
Biol. Chem. 382:1001-1006(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete genome sequence of Thermus thermophilus HB8."
Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S.
Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HB8 / ATCC 27634 / DSM 579.
[3]"Isolation and characterization of a new ribosomal protein from the thermophilic eubacteria, Thermus thermophilus, T. aquaticus and T. flavus."
Choli T., Franceschi F., Yonath A., Wittmann-Liebold B.
Biol. Chem. Hoppe-Seyler 374:377-383(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-27.
[4]"Purification and characterization of the 30S ribosomal proteins from the bacterium Thermus thermophilus."
Tsiboli P., Herfurth E., Choli T.
Eur. J. Biochem. 226:169-177(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: PROTEIN SEQUENCE OF 2-27.
[5]"Extending ribosomal protein identifications to unsequenced bacterial strains using matrix-assisted laser desorption/ionization mass spectrometry."
Suh M.-J., Hamburg D.M., Gregory S.T., Dahlberg A.E., Limbach P.A.
Proteomics 5:4818-4831(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: MASS SPECTROMETRY.
[6]"Structure of the 30S ribosomal subunit."
Wimberly B.T., Brodersen D.E., Clemons W.M. Jr., Morgan-Warren R.J., Carter A.P., Vonrhein C., Hartsch T., Ramakrishnan V.
Nature 407:327-339(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF THE 30S SUBUNIT.
[7]"The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit."
Brodersen D.E., Clemons W.M. Jr., Carter A.P., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V.
Cell 103:1143-1154(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.3 ANGSTROMS) OF THE 30S SUBUNIT.
[8]"Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics."
Carter A.P., Clemons W.M. Jr., Brodersen D.E., Morgan-Warren R.J., Wimberly B.T., Ramakrishnan V.
Nature 407:340-348(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.0 ANGSTROMS) OF THE 30S SUBUNIT.
[9]"The path of messenger RNA through the ribosome."
Yusupova G.Z., Yusupov M.M., Cate J.H.D., Noller H.F.
Cell 106:233-241(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (5.0 ANGSTROMS) OF THE RIBOSOME.
[10]"Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3."
Pioletti M., Schluenzen F., Harms J., Zarivach R., Gluehmann M., Avila H., Bashan A., Bartels H., Auerbach T., Jacobi C., Hartsch T., Yonath A., Franceschi F.
EMBO J. 20:1829-1839(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF THE 30S SUBUNIT.
[11]"Crystal structure of an initiation factor bound to the 30S ribosomal subunit."
Carter A.P., Clemons W.M. Jr., Brodersen D.E., Morgan-Warren R.J., Hartsch T., Wimberly B.T., Ramakrishnan V.
Science 291:498-501(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF THE 30S SUBUNIT.
[12]"Crystal structure of the ribosome at 5.5 A resolution."
Yusupov M.M., Yusupova G.Z., Baucom A., Lieberman K., Earnest T.N., Cate J.H.D., Noller H.F.
Science 292:883-896(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (5.5 ANGSTROMS) OF THE RIBOSOME.
[13]"Recognition of cognate transfer RNA by the 30S ribosomal subunit."
Ogle J.M., Brodersen D.E., Clemons W.M. Jr., Tarry M.J., Carter A.P., Ramakrishnan V.
Science 292:897-902(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.11 ANGSTROMS) OF THE 30S SUBUNIT.
[14]"Crystal structure of the 30S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16S RNA."
Brodersen D.E., Clemons W.M. Jr., Carter A.P., Wimberly B.T., Ramakrishnan V.
J. Mol. Biol. 316:725-768(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (3.05 ANGSTROMS) OF THE 30S SUBUNIT.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ295159 Genomic DNA. Translation: CAC15068.1.
AP008226 Genomic DNA. Translation: BAD71219.1.
PIRS33869.
RefSeqYP_144662.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1FJGX-ray3.00V2-27[»]
1GIXX-ray5.50X2-27[»]
1HNWX-ray3.40V2-27[»]
1HNXX-ray3.40V2-27[»]
1HNZX-ray3.30V2-27[»]
1HR0X-ray3.20V2-27[»]
1I94X-ray3.20U2-27[»]
1I95X-ray4.50U2-27[»]
1I96X-ray4.20U2-27[»]
1I97X-ray4.50U2-27[»]
1IBKX-ray3.31V2-27[»]
1IBLX-ray3.11V2-27[»]
1IBMX-ray3.31V2-27[»]
1J5EX-ray3.05V2-27[»]
1JGOX-ray5.60X2-27[»]
1JGPX-ray7.00X2-27[»]
1JGQX-ray5.00X2-27[»]
1L1Umodel-V1-25[»]
1ML5electron microscopy14.00X2-27[»]
1N32X-ray3.00V2-27[»]
1N33X-ray3.35V2-27[»]
1N34X-ray3.80V2-27[»]
1N36X-ray3.65V2-27[»]
1XMOX-ray3.25V1-27[»]
1XMQX-ray3.00V1-27[»]
1XNQX-ray3.05V1-27[»]
1XNRX-ray3.10V1-27[»]
1YL4X-ray5.50X1-27[»]
2B64X-ray5.90U1-27[»]
2B9MX-ray6.76U1-27[»]
2B9OX-ray6.46U1-27[»]
2E5LX-ray3.30V2-27[»]
2HGIX-ray5.00X1-27[»]
2HGPX-ray5.50X1-27[»]
2HGRX-ray4.51X1-27[»]
2HHHX-ray3.35U1-27[»]
2J00X-ray2.80U1-27[»]
2J02X-ray2.80U1-27[»]
2OW8X-ray3.71v-[»]
2UU9X-ray3.10U1-27[»]
2UUAX-ray2.90U1-27[»]
2UUBX-ray2.90U1-27[»]
2UUCX-ray3.10U1-27[»]
2UXBX-ray3.10U1-27[»]
2UXCX-ray2.90U1-27[»]
2UXDX-ray3.20V1-27[»]
2V46X-ray3.80U1-27[»]
2V48X-ray3.80U1-27[»]
2VQEX-ray2.50U1-27[»]
2VQFX-ray2.90U1-27[»]
2WDGX-ray3.30U1-27[»]
2WDHX-ray3.30U1-27[»]
2WDKX-ray3.50U1-27[»]
2WDMX-ray3.50U1-27[»]
2WH1X-ray3.45U1-27[»]
2WH3X-ray3.45U1-27[»]
2WRIX-ray3.60U1-27[»]
2WRKX-ray3.60U1-27[»]
2WRNX-ray3.60U1-27[»]
2WRQX-ray3.60U1-27[»]
2X9RX-ray3.10U1-27[»]
2X9TX-ray3.10U1-27[»]
2XFZX-ray3.20U1-27[»]
2XG1X-ray3.20U1-27[»]
2XQDX-ray3.10U1-27[»]
2XSYelectron microscopy7.80U1-27[»]
2XUYelectron microscopy7.60U1-27[»]
2Y0UX-ray3.10U1-27[»]
2Y0WX-ray3.10U1-27[»]
2Y0YX-ray3.10U1-27[»]
2Y10X-ray3.10U1-27[»]
2Y12X-ray3.10U1-27[»]
2Y14X-ray3.10U1-27[»]
2Y16X-ray3.10U1-27[»]
2Y18X-ray3.10U1-27[»]
2ZM6X-ray3.30V2-27[»]
3FICelectron microscopy6.40U2-26[»]
3HUWX-ray3.10U1-27[»]
3HUYX-ray3.10U1-27[»]
3I8GX-ray3.10X1-27[»]
3I8HX-ray3.10X1-27[»]
3I9BX-ray3.50X1-27[»]
3I9DX-ray3.50X1-27[»]
3KIQX-ray3.30u1-27[»]
3KISX-ray3.30u1-27[»]
3KIUX-ray3.60u1-27[»]
3KIXX-ray3.60u1-27[»]
3KNHX-ray3.00U1-27[»]
3KNJX-ray3.15U1-27[»]
3KNLX-ray3.45U1-27[»]
3KNNX-ray3.45U1-27[»]
3OGEX-ray3.00U1-27[»]
3OGYX-ray3.00U1-27[»]
3OHCX-ray3.00U1-27[»]
3OHDX-ray3.00U1-27[»]
3OHYX-ray3.00U1-27[»]
3OI0X-ray3.00U1-27[»]
3OI2X-ray3.10U1-27[»]
3OI4X-ray3.10U1-27[»]
3OTOX-ray3.69U1-27[»]
3T1HX-ray3.11V1-27[»]
3T1YX-ray2.80V1-27[»]
3TVFX-ray3.10X1-27[»]
3TVGX-ray3.10X1-27[»]
3UXSX-ray3.20U1-27[»]
3UXTX-ray3.20U1-27[»]
3UYDX-ray3.00X1-27[»]
3UYFX-ray3.00X1-27[»]
3UZ3X-ray3.30X1-27[»]
3UZ4X-ray3.30X1-27[»]
3UZ6X-ray3.00X1-27[»]
3UZ7X-ray3.00X1-27[»]
3UZGX-ray3.30X1-27[»]
3UZIX-ray3.30X1-27[»]
3UZLX-ray3.30X1-27[»]
3UZMX-ray3.30X1-27[»]
3V22X-ray3.00U1-27[»]
3V24X-ray3.00U1-27[»]
3V26X-ray3.10U1-27[»]
3V28X-ray3.10U1-27[»]
3V2CX-ray2.70U1-27[»]
3V2EX-ray2.70U1-27[»]
3V6UX-ray3.90U1-27[»]
3V6VX-ray3.90U1-27[»]
3ZN7X-ray3.10U1-27[»]
3ZNDX-ray3.10U1-27[»]
3ZVOX-ray3.80U1-27[»]
4ABRX-ray3.10U1-27[»]
4AQYX-ray3.50V2-27[»]
4B3MX-ray2.90V2-27[»]
4B3RX-ray3.00V2-27[»]
4B3SX-ray3.15V2-27[»]
4B3TX-ray3.00V2-27[»]
4B8FX-ray3.70U1-27[»]
4B8HX-ray3.70U1-27[»]
4BTCX-ray2.95U1-27[»]
4BYDX-ray3.35U1-27[»]
4DH9X-ray3.20U1-27[»]
4DHBX-ray3.20U1-27[»]
4DR1X-ray3.60U1-27[»]
4DR2X-ray3.25U1-27[»]
4DR3X-ray3.35U1-27[»]
4DR4X-ray3.97U1-27[»]
4DR5X-ray3.45U1-27[»]
4DR6X-ray3.30U1-27[»]
4DR7X-ray3.75U1-27[»]
4DUYX-ray3.39U1-27[»]
4DUZX-ray3.65U1-27[»]
4DV0X-ray3.85U1-27[»]
4DV1X-ray3.85U1-27[»]
4DV2X-ray3.65U1-27[»]
4DV3X-ray3.55U1-27[»]
4DV4X-ray3.65U1-27[»]
4DV5X-ray3.68U1-27[»]
4DV6X-ray3.30U1-27[»]
4DV7X-ray3.29U1-27[»]
4EJ9X-ray3.52U1-27[»]
4EJAX-ray3.52U1-27[»]
4G5KX-ray3.30X1-27[»]
4G5MX-ray3.30X1-27[»]
4G5TX-ray3.10X1-27[»]
4G5VX-ray3.10X1-27[»]
4GKJX-ray3.30V2-25[»]
4GKKX-ray3.20V2-25[»]
4JI0X-ray3.49U1-27[»]
4JI1X-ray3.14U1-27[»]
4JI2X-ray3.64U1-27[»]
4JI3X-ray3.35U1-27[»]
4JI4X-ray3.69U1-27[»]
4JI5X-ray3.85U1-27[»]
4JI6X-ray3.55U1-27[»]
4JI7X-ray3.50U1-27[»]
4JI8X-ray3.74U1-27[»]
4JUWX-ray2.86U2-25[»]
4JV5X-ray3.16U2-25[»]
4JYAX-ray3.10U2-25[»]
4K0KX-ray3.40U2-26[»]
4K0LX-ray3.30U2-25[»]
4K0PX-ray3.30U2-25[»]
4KHPX-ray3.10U2-25[»]
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaBAD71219; BAD71219; BAD71219.
GeneID3168745.
KEGGttj:TTHA1396.

Phylogenomic databases

eggNOGNOG262440.
ProtClustDBPRK14753.

Enzyme and pathway databases

BioCycTTHE300852:GH8R-1432-MONOMER.

Family and domain databases

ProtoNetSearch...

Other

EvolutionaryTraceQ5SIH3.

Entry information

Entry nameRSHX_THET8
AccessionPrimary (citable) accession number: Q5SIH3
Entry history
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: January 23, 2007
Last modified: January 22, 2014
This is version 78 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

PDB cross-references

Index of Protein Data Bank (PDB) cross-references