Arginase - Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Preferred order of sections

Names and origin

Protein names

Submitted name:
Arginase EMBL BAD71319.1

Gene names

Ordered Locus Names:

TTHA1496

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	291 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Technical term	3D-structure PDB 2EF5 PDB 2EIV PDB 2EF4 Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	arginine metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	arginase activity Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Sites

Metal binding

97

1

Manganese 1; via pros nitrogen PDB 2EF5

Metal binding

119

1

Manganese 1 PDB 2EF5

Metal binding

119

1

Manganese 2 PDB 2EF5

Metal binding

121

1

Manganese 2; via pros nitrogen PDB 2EF5

Metal binding

123

1

Manganese 1 PDB 2EF5

Metal binding

218

1

Manganese 1 PDB 2EF5

Metal binding

218

1

Manganese 2 PDB 2EF5

Metal binding

220

1

Manganese 2 PDB 2EF5

Sequences

Sequence

Length

Mass (Da)

Tools

Q5SI78 [UniParc].

Last modified December 21, 2004. Version 1.
Checksum: EC505E6C4C27A40B
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FASTA

291

31,229

        10         20         30         40         50         60 
MERVAVVGVP MDLGANRRGV DMGPSALRYA RLLEQLEDLG YTVEDLGDVP VSLARASRRR 

        70         80         90        100        110        120 
GRGLAYLEEI RAAALVLKER LAALPEGVFP IVLGGDHSLS MGSVAGAARG RRVGVVWVDA 

       130        140        150        160        170        180 
HADFNTPETS PSGNVHGMPL AVLSGLGHPR LTEVFRAVDP KDVVLVGVRS LDPGEKRLLK 

       190        200        210        220        230        240 
EAGVRVYTMH EVDRLGVARI AEEVLKHLQG LPLHVSLDAD VLDPTLAPGV GTPVPGGLTY 

       250        260        270        280        290 
REAHLLMEIL AESGRVQSLD LVEVNPILDE RNRTAEMLVG LALSLLGKRI F

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.
[2]	"Crystal structure of the arginase from thermus thermophilus." Kumarevel T.S., Karthe P., Kuramitsu S., Yokoyama S. Submitted (FEB-2007) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 2-291.
[3]	"Crystal Structure of the arginase from Thermus thermophilus." Kumarevel T.S., Karthe P., Kuramitsu S., Yokoyama S. Submitted (MAR-2007) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.91 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AP008226 Genomic DNA. Translation: BAD71319.1.

RefSeq

YP_144762.1. NC_006461.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2EF4	X-ray	2.30	A	2-291	[»]
2EF5	X-ray	2.00	A/B/D/E/F/G	2-291	[»]
2EIV	X-ray	2.91	A/C/D/E/F/G/H/I/J/K/L/M	1-291	[»]

ProteinModelPortal

Q5SI78.

SMR

Q5SI78. Positions 2-291.

ModBase

Search...

Protein-protein interaction databases

STRING

Q5SI78.

Protocols and materials databases

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

GeneID

3169704.

GenomeReviews

Gene locus TTHA1496 in contig AP008226_GR.

KEGG

ttj:TTHA1496.

PATRIC

23957953. VBITheThe93045_1471.

Phylogenomic databases

eggNOG

COG0010.

HOGENOM

HBG391953.

OMA

ADIPNDS.

ProtClustDB

CLSK799232.

Enzyme and pathway databases

BioCyc

TTHE300852:TTHA1496-MONOMER.

Family and domain databases

InterPro

IPR014033. Arginase_subgr.
IPR006035. Ureohydrolase.
IPR023696. Ureohydrolase_domain.
[Graphical view]

Gene3D

G3DSA:3.40.800.10. Ureohydrolase. 1 hit.

KO

K01476.

PANTHER

PTHR11358:SF2. Arginase_sub. 1 hit.
PTHR11358. Ureohydrolase. 1 hit.

Pfam

PF00491. Arginase. 1 hit.
[Graphical view]

PIRSF

PIRSF036979. Arginase. 1 hit.

PRINTS

PR00116. ARGINASE.

TIGRFAMs

TIGR01229. RocF_arginase. 1 hit.

PROSITE

PS51409. ARGINASE_2. 1 hit.
[Graphical view]

ProtoNet

Search...

Entry information

Entry name

Q5SI78_THET8

Accession

Primary (citable) accession number: Q5SI78

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	December 14, 2011
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)