Q5SI04 (Q5SI04_THET8) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Glutamate dehydrogenase PIRNR PIRNR000185

Gene names

Ordered Locus Names:

TTHA1576

Organism

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)

Taxonomic identifier

300852 [NCBI]

Taxonomic lineage

Bacteria › Deinococcus-Thermus › Deinococci › Thermales › Thermaceae › Thermus

Protein attributes

Sequence length	424 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the Glu/Leu/Phe/Val dehydrogenases family. RuleBase RU004417 PIRNR PIRNR000185

Ontologies

Keywords
Molecular function	Oxidoreductase RuleBase RU004418 PIRNR PIRNR000185
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular amino acid metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	114	1	By similarity PIRSR PIRSR000185-1

Sequences

	Sequence		Length	Mass (Da)
	Q5SI04 [UniParc]. Last modified December 21, 2004. Version 1. Checksum: 0D5615C6FE86D3F4	FASTA	424	46,039
	10 20 30 40 50 60 MKSEPLSYLG KDGGPWEIFT EQVDRVVPYL GRLAPLAESL KRPKRVLIVD VPVRLDDGSV 70 80 90 100 110 120 AYFEGYRVHH NTARGPAKGG VRYHPEVTLS EVMALAGWMT IKNAAVGLPY GGGKGGIRVD 130 140 150 160 170 180 PRKLSPGELE RLTRRYTSEI GILLGPDRDI PAPDVNTGER EMAWMMDTYS MNVGRTVPGV 190 200 210 220 230 240 VTGKPIALGG SLGRRDATGR GVFITAAAAA EKIGLQVEGA RVAIQGFGNV GNAAARAFHD 250 260 270 280 290 300 HGARVVAVQD HTGTVYNEAG IDPYDLLRYV QEFGGVRGYP KAEPLPAADF WGLPVEFLVP 310 320 330 340 350 360 AALEKQITEQ NAWRIRARIV AEGANGPTTP AADDILLEKG VLVVPDVIAN AGGVTVSYFE 370 380 390 400 410 420 WVQDFNSYFW TEEEINARLE RVLRNAFGAV WQVAQEKKIP LRTAAYVVAA TRVLEAQALR GLYP

References

[1]

"Complete genome sequence of Thermus thermophilus HB8." Masui R., Kurokawa K., Nakagawa N., Tokunaga F., Koyama Y., Shibata T., Oshima T., Yokoyama S., Yasunaga T., Kuramitsu S. Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HB8 / ATCC 27634 / DSM 579.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AP008226 Genomic DNA. Translation: BAD71399.1.
RefSeq	YP_144842.1. NC_006461.1.
3D structure databases
ProteinModelPortal	Q5SI04.
SMR	Q5SI04. Positions 15-421.
ModBase	Search...
Protein-protein interaction databases
STRING	Q5SI04.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3169142.
GenomeReviews	Gene locus TTHA1576 in contig AP008226_GR.
KEGG	ttj:TTHA1576.
NMPDR	fig|300852.3.peg.1888.
PATRIC	23958109. VBITheThe93045_1547.
Phylogenomic databases
eggNOG	COG0334.
HOGENOM	HBG590661.
OMA	CPDVIAN.
PhylomeDB	Q5SI04.
ProtClustDB	CLSK704217.
Enzyme and pathway databases
BioCyc	TTHE300852:TTHA1576-MONOMER.
Family and domain databases
InterPro	IPR006095. Glu/Leu/Phe/Val_DH. IPR006096. Glu/Leu/Phe/Val_DH_C. IPR006097. Glu/Leu/Phe/Val_DH_dimer_dom. IPR014362. Glu_DH. IPR016040. NAD(P)-bd_dom. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00261.
Pfam	PF00208. ELFV_dehydrog. 1 hit. PF02812. ELFV_dehydrog_N. 1 hit. [Graphical view]
PIRSF	PIRSF000185. Glu_DH. 1 hit.
PRINTS	PR00082. GLFDHDRGNASE.
SMART	SM00839. ELFV_dehydrog. 1 hit. [Graphical view]
PROSITE	PS00074. GLFV_DEHYDROGENASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q5SI04_THET8

Accession

Primary (citable) accession number: Q5SI04

Entry history

Integrated into UniProtKB/TrEMBL:	December 21, 2004
Last sequence update:	December 21, 2004
Last modified:	December 14, 2011
This is version 50 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)